Search Results - "Demitrack, Elise"

Notch regulation of gastrointestinal stem cells by Demitrack, Elise S., Samuelson, Linda C.

“…The gastrointestinal (GI) tract epithelium is continuously replenished by actively cycling stem and progenitor cells. These cell compartments are regulated to…”
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Notch receptor regulation of intestinal stem cell homeostasis and crypt regeneration by Carulli, Alexis J., Keeley, Theresa M., Demitrack, Elise S., Chung, Jooho, Maillard, Ivan, Samuelson, Linda C.

“…The Notch signaling pathway regulates intestinal epithelial cell homeostasis, including stem cell maintenance, progenitor cell proliferation and…”
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Notch signaling regulates gastric antral LGR5 stem cell function by Demitrack, Elise S, Gifford, Gail B, Keeley, Theresa M, Carulli, Alexis J, VanDussen, Kelli L, Thomas, Dafydd, Giordano, Thomas J, Liu, Zhenyi, Kopan, Raphael, Samuelson, Linda C

“…The major signaling pathways regulating gastric stem cells are unknown. Here we report that Notch signaling is essential for homeostasis of LGR5 + antral stem…”
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Notch as a Driver of Gastric Epithelial Cell Proliferation by Demitrack, Elise S, Samuelson, Linda C

“…The gastric epithelium is sustained by a population of stem cells that replenish the various mature epithelial lineages throughout adulthood. Regulation of…”
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Notch1 and Notch2 receptors regulate mouse and human gastric antral epithelial cell homoeostasis by Gifford, Gail B, Demitrack, Elise S, Keeley, Theresa M, Tam, Andrew, La Cunza, Nilsa, Dedhia, Priya H, Spence, Jason R, Simeone, Diane M, Saotome, Ichiko, Louvi, Angeliki, Siebel, Christian W, Samuelson, Linda C

“…We tested the ability of Notch pathway receptors Notch1 and Notch2 to regulate stem and epithelial cell homoeostasis in mouse and human gastric antral tissue…”
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NOTCH1 and NOTCH2 regulate epithelial cell proliferation in mouse and human gastric corpus by Demitrack, Elise S, Gifford, Gail B, Keeley, Theresa M, Horita, Nobukatsu, Todisco, Andrea, Turgeon, D Kim, Siebel, Christian W, Samuelson, Linda C

“…The Notch signaling pathway is known to regulate stem cells and epithelial cell homeostasis in gastrointestinal tissues; however, Notch function in the corpus…”
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Gastrin induces parathyroid hormone-like hormone expression in gastric parietal cells by Al Menhali, Asma, Keeley, Theresa M, Demitrack, Elise S, Samuelson, Linda C

“…Parietal cells play a fundamental role in stomach maintenance, not only by creating a pathogen-free environment through the production of gastric acid, but…”
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Inhibitors of acid secretion can benefit gastric wound repair independent of luminal pH effects on the site of damage by Demitrack, Elise S, Aihara, Eitaro, Kenny, Susan, Varro, Andrea, Montrose, Marshall H

“…The authors' goal was to measure pH at the gastric surface (pH₀) to understand how acid secretion affects the repair of microscopic injury to the gastric…”
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Invasive mouse gastric adenocarcinomas arising from Lgr5+ stem cells are dependent on crosstalk between the Hedgehog/GLI2 and mTOR pathways by Syu, Li-Jyun, Zhao, Xinyi, Zhang, Yaqing, Grachtchouk, Marina, Demitrack, Elise, Ermilov, Alexandre, Wilbert, Dawn M, Zheng, Xinlei, Kaatz, Ashley, Greenson, Joel K, Gumucio, Deborah L, Merchant, Juanita L, di Magliano, Marina Pasca, Samuelson, Linda C, Dlugosz, Andrzej A

“…Gastric adenocarcinoma is the third most common cause of cancer-related death worldwide. Here we report a novel, highly-penetrant mouse model of invasive…”
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IFNγ contributes to the development of gastric epithelial cell metaplasia in Huntingtin interacting protein 1 related (Hip1r)-deficient mice by Liu, Zhiping, Demitrack, Elise S, Keeley, Theresa M, Eaton, Kathryn A, El-Zaatari, Mohamad, Merchant, Juanita L, Samuelson, Linda C

“…Huntingtin interacting protein 1 related (Hip1r) is an F-actin- and clathrin-binding protein involved in vesicular trafficking that is crucial for parietal…”
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Disruption of the Cox-1 gene slows repair of microscopic lesions in the mouse gastric epithelium by Starodub, Olga T, Demitrack, Elise S, Baumgartner, Heidi K, Montrose, Marshall H

“…Cyclooxygenase-1 (Cox-1) contributes to gastric defense of healthy tissue, but the role in the protection of the gastric epithelium after minor, acute damage…”
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Notch Regulates Gastric Antral [Lgr5.sup.+] Stem Cells to Control Epithelial Cell Homeostasis by Demitrack, Elise S, Gifford, Gail B, Samuelson, Linda C

“…Background/Aim: The Notch signaling pathway regulates epithelial cell proliferation in the stomach; however it is unknown how Notch functions in gastric stem…”
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Abstract 913: Wnt signaling promotes mouse and human gastric stem cell proliferation by Demitrack, Elise Susan, Samuelson, Linda C.

“…Background: The Wnt signaling pathway is required for proliferation of intestinal stem cells and activating mutations in the Wnt pathway can promote colorectal…”
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Notch and mTORC1 Regulate Growth of Human Gastric Cancer Cells and Human Gastric Organoids by Wong, Gabriela, Demitrack, Elise S, Samuelson, Linda C

“…Abstract only…”
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Notch and mTOR Regulate Proliferation of Human Gastric Cancer Cells by Wong, Gabriela, Demitrack, Elise S, Samuelson, Linda C

“…Abstract only…”
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Abstract 1711: Notch and mTORC1 regulate human gastric stem cell function during normal tissue homeostasis and gastric cancer by Demitrack, Elise S., Gifford, Gail B., Wong, Gabriela, Samuelson, Linda C.

“…Notch and mTOR pathway activation have been observed in human gastric cancers. We have recently shown that chronic Notch activation induces gastric stem cell…”
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Gastric antral organoids are sustained by intrinsic Notch signaling (1119.1) by Gifford, Gail, Demitrack, Elise, Spence, Jason, Simeone, Diane, Samuelson, Linda

“…The gastric epithelium undergoes constant turnover, with adult stem cells replenishing mature cell types to maintain homeostasis. The Notch signaling pathway…”
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191 Notch Signaling Induces LGR5+ Antral Stem Cell Proliferation and Tumorigenesis via Activation of mTOR by Demitrack, Elise, Thomas, Dafydd, Giordano, Thomas J, Samuelson, Linda C

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357 - Regulation of CD44 Expression by Bone Morphogenetic Protein (BMP) Signaling and Inflammatory Stimuli by Ye, Wei, Takabayashi, Hidehiko, Yang, Yitian, Mao, Maria Y., Samuelson, Linda C., Demitrack, Elise, Huang, Fung-yu, Chu, Kent-Man, Leung, Wai K., Todisco, Andrea

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361 Notch Regulates Gastric Antral LGR5+ Stem Cells to Control Epithelial Cell Homeostasis by Demitrack, Elise, Gifford, Gail B, Samuelson, Linda C

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