Search Results - "Demirdöğen, Birsen Can"

Neurocognitive impairment in multiple sclerosis and its association with thiol‐disulfide homeostasis and ischemia‐modified albumin by Can Demirdöğen, Birsen, Kiliç, Osman Oğuzhan, Yilmaz, Ata Ayhan, Mungan, Semra, Neşelioğlu, Salim, Erel, Özcan

“…This study aimed to assess the possible association between cognitive impairment and two important biochemical biomarkers of oxidative stress, thiol‐disulfide…”
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Association of cholesterol 7α-hydroxylase (CYP7A1) promoter polymorphism (rs3808607) and cholesterol 24S-hydroxylase (CYP46A1) intron 2 polymorphism (rs754203) with serum lipids, vitamin D levels, and multiple sclerosis risk in the Turkish population by Sezer, Eda, Can Demirdöğen, Birsen, Demirkaya, Şeref, Bulut, Giray, Akkulak, Merve, Evin, Emre, Adalı, Orhan

“…Background Patients with multiple sclerosis (MS) have significantly lower vitamin D levels. Cholesterol is known to be the precursor for vitamin D synthesis,…”
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Single nucleotide variants around the connective tissue growth factor (CTGF/CCN2) gene and their association with multiple sclerosis risk, disability scores, and rate of disease progression by Can Demirdöğen, Birsen, Kılıç, Osman Oğuzhan, Karagülle, Elif Naz, Kalmaz, Latife Mekselina, Mungan, Semra

“…Background This study aimed to explore the possible association of single nucleotide polymorphisms (SNPs) in the upstream (rs9402373) and downstream regions…”
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Paraoxonase 1 (PON1) promoter (−107T/C) and coding region (192Q/R and 55L/M) genetic variations in pseudoexfoliation syndrome and pseudoexfoliative glaucoma risk by Can Demirdöğen, Birsen, Koçan Akçin, Canan, Göksoy, Ezgi, Yakar, Gizem, Öztepe, Tuğçe, Demirkaya-Budak, Sinem, Oflaz, Sinan

“…Purpose Pseudoexfoliation syndrome (PEX) is characterized by the accumulation of microscopic extracellular material in the anterior chamber of the eye and can…”
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Missense Genetic Polymorphisms of Microsomal ( EPHX1 ) and Soluble Epoxide Hydrolase ( EPHX2 ) and Their Relation to the Risk of Large Artery Atherosclerotic Ischemic Stroke in a Turkish Population by Can Demirdöğen, Birsen, Miçooğulları, Yağmur, Türkanoğlu Özçelik, Aysun, Adalı, Orhan

“…Soluble epoxide hydrolase (sEH) and microsomal epoxide hydrolase (mEH) both catalyze the metabolism of epoxyeicosatrienoic acids (EETs), lipid signaling…”
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Influence of clusterin genetic variants on IOP elevation in pseudoexfoliation syndrome and pseudoexfoliative glaucoma in Turkish population by Demirdöğen, Birsen Can, Demirkaya-Budak, Sinem

“…Pseudoexfoliation syndrome (PEX) is distinguished by the deposition of fibrillary material within the aqueous humor and, in most cases, causes…”
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Biomarkers of NRF2 signalling: Current status and future challenges by Morgenstern, Christina, Lastres-Becker, Isabel, Demirdöğen, Birsen Can, Costa, Vera Marisa, Daiber, Andreas, Foresti, Roberta, Motterlini, Roberto, Kalyoncu, Sibel, Arioz, Burak I., Genc, Sermin, Jakubowska, Monika, Trougakos, Ioannis P., Piechota-Polanczyk, Aleksandra, Mickael, Michel, Santos, Marlene, Kensler, Thomas W., Cuadrado, Antonio, Copple, Ian M.

“…The cytoprotective transcription factor NRF2 regulates the expression of several hundred genes in mammalian cells and is a promising therapeutic target in a…”
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Flavin containing monooxygenase 3 genetic polymorphisms Glu158Lys and Glu308Gly and their relation to ischemic stroke by Türkanoğlu Özçelik, Aysun, Can Demirdöğen, Birsen, Demirkaya, Şeref, Adalı, Orhan

“…Ischemic stroke is a multifactorial disease leading to severe long-term disability and it is the third leading cause of death in developed countries. Although…”
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The effects of hydraulic calcium silicate containing endodontic materials on oxidative stress in erythrocytes and liver by Demirkaya, Kadriye, Can Demirdöğen, Birsen, Öncel Torun, Zeynep, Erdem, Onur, Tunca, Yaşar Meriç

“…Abstract Objective The aim of this study was to evaluate the effects of hydraulic calcium silicate endodontic cements, MTA Angelus, MTA Fillapex, and Theracal…”
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Potential role of calcifying nanoparticles in the etiology of multiple sclerosis by Can Demirdöğen, Birsen

“…Nanobacteria or calcifying nanoparticles are 80–500 nm sized nano-organisms that are physically associated with carbonate apatite mineral formations. They have…”
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Association analysis of GSTT1, GSTM1 genotype polymorphisms and serum total GST activity with ischemic stroke risk by Türkanoğlu, Aysun, Can Demirdöğen, Birsen, Demirkaya, Şeref, Bek, Semai, Adalı, Orhan

“…Oxidative stress plays a major role in pathogenesis of atherosclerosis which is responsible for stroke. Glutathione S -transferases (GSTs) detoxify metabolites…”
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Evaluation of oxidative stress and paraoxonase phenotypes in pseudoexfoliation syndrome and pseudoexfoliation glaucoma by Demirdögen, Birsen Can, Ceylan, Osman Melih, Işikoğlu, Semra, Mumcuoğlu, Tarkan, Erel, Ozcan

“…Our purpose was to determine whether total oxidant and antioxidant status, total thiol levels and activities of serum paraoxonase 1, an HDL-associated…”
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Theranostic potential of graphene quantum dots for multiple sclerosis by Demirdöğen, Birsen Can

“…Nanomedicine offers great promise to solve healthcare problems using nanotechnology. Theranostics provide imaging/diagnosis and therapy simultaneously. Novel…”
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A literature review of biosensors for multiple sclerosis: Towards personalized medicine and point-of-care testing by Can Demirdöğen, Birsen

“…•There is a need for robust biomarkers for MS diagnosis and prognosis.•Point-of-care testing (POCT) provides quick results via handheld or bench-top…”
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Analysis of paraoxonase 1 (PON1) genetic polymorphisms and activities as risk factors for ischemic stroke in Turkish population by Demirdöğen, Birsen Can, Demirkaya, Şeref, Türkanoğlu, Aysun, Bek, Semai, Arınç, Emel, Adalı, Orhan

“…Background Paraoxonase1 (PON1) is protective against the development of atherosclerosis, a risk factor for ischemic stroke. PON1 gene has one promoter region…”
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Apolipoprotein A5 polymorphisms in Turkish population: association with serum lipid profile and risk of ischemic stroke by Can Demirdöğen, Birsen, Şahin, Esra, Türkanoğlu Özçelik, Aysun, Bek, Semai, Demirkaya, Şeref, Adali, Orhan

“…Atherosclerosis, a major cause of ischemic stroke, may be associated with variability of triglyceride (TG) levels. Apolipoprotein A5 ( APOA5 ) genetic…”
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Evaluation of tear and aqueous humor level, and genetic variants of connective tissue growth factor as biomarkers for early detection of pseudoexfoliation syndrome/glaucoma by Can Demirdöğen, Birsen, Koçan Akçin, Canan, Özge, Gökhan, Mumcuoğlu, Tarkan

“…Pseudoexfoliation syndrome (PEX) may lead to the development of pseudoexfoliative glaucoma (PEG), a potential cause of irreversible blindness, if left…”
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Evaluation of Tear Fluid and Aqueous Humor Concentration of Clusterin as Biomarkers for Early Diagnosis of Pseudoexfoliation Syndrome and Pseudoexfoliative Glaucoma by Can Demirdöğen, Birsen, Demirkaya-Budak, Sinem, Özge, Gökhan, Mumcuoğlu, Tarkan

“…Pseudoexfoliation syndrome (PEX) is an age-related disorder of the extracellular matrix characterized by the accumulation of fibrillary deposits in the…”
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Characterization and modulation by drugs of sheep liver microsomal flavin monooxygenase activity by Can Demirdöğen, Birsen, Adalı, Orhan

“…The flavin monooxygenases (FMO) catalyse the NADPH and oxygen‐dependent oxidation of a wide range of nucleophilic nitrogen‐, sulfur‐, phosphorus‐, and selenium…”
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In vivo evaluation of the effects of hydraulic calcium silicate dental cements on plasma and liver aluminium levels in rats by Demirkaya, Kadriye, Can Demirdöğen, Birsen, Öncel Torun, Zeynep, Erdem, Onur, Çetinkaya, Serdar, Akay, Cemal

“…Our aim was to test whether the presence of three hydraulic calcium silicate dental cements – MTA Angelus, MTA Fillapex, and Theracal LC – in the dental…”
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