Search Results - "Demirbolat, Gülen Melike"

Green synthesis of silver nanoparticles via Cynara scolymus leaf extracts: The characterization, anticancer potential with photodynamic therapy in MCF7 cells by Erdogan, Omer, Abbak, Muruvvet, Demirbolat, Gülen Melike, Birtekocak, Fatih, Aksel, Mehran, Pasa, Salih, Cevik, Ozge

“…In this study, we report on the synthesis of silver nanoparticles (AgNPs) from the leaf extracts of Cynara scolymus (Artichoke) using microwave irradiation and…”
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Electrospun Nanofibers for Dual and Local Delivery of Neuroprotective Drugs by Haidar, Mohammad Karim, Timur, Selin Seda, Demirbolat, Gülen Melike, Nemutlu, Emirhan, Gürsoy, R. Neslihan, Ulubayram, Kezban, Öner, Levent, Eroğlu, Hakan

“…Drug delivery for neuroprotection/neuroregeneration after traumatic peripheral nerve injuries still remains a challenge. For this purpose, we formulated…”
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Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of paclitaxel by Abas, Burcin Irem, Demirbolat, Gulen Melike, Cevik, Ozge

“…Mesenchymal stem cells can be obtained and multiplied from various sources and have a very high capacity to release exosomes. Exosomes are nano-sized…”
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Wharton jelly-derived mesenchymal stem cell exosomes induce apoptosis and suppress EMT signaling in cervical cancer cells as an effective drug carrier system of paclitaxel by Burcin Irem Abas, Gulen Melike Demirbolat, Ozge Cevik

“…Mesenchymal stem cells can be obtained and multiplied from various sources and have a very high capacity to release exosomes. Exosomes are nano-sized…”
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Raloxifene-loaded and aptamer-bonded exosomes induce autophagic and apoptotic death in HeLa cells by enhancing the lysosomotropic effect by ERDOGAN, OMER, MELIKE DEMIRBOLAT, GULEN, CEVIK, OZGE

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PEG4000 modified liposomes enhance the solubility of quercetin and improve the liposome functionality: in vitro characterization and the cellular efficacy by Demirbolat, Gülen Melike, Erdoğan, Ömer, Coşkun, Göknil Pelin, Çevik, Özge

“…Quercetin, a multifunctional therapeutic agent, is used in various types of cancer. However, its therapeutic effect is limited by virtue of poorly aqueous…”
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EVALUATION OF SUSTAINED RELEASE FROM FLUORIDE-LOADED CARBON NANOTUBES by Varol, Selen Esin, Bodur, Haluk, Demirbolat, Gülen Melike, Degim, Ismail Tuncer

“…The developments in nanotechnology have led to significant advances in many areas of science and technology including medical sciences and dentistry. Carbon…”
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In vitro hepatotoxicity evaluation of methotrexate-loaded niosome formulation: fabrication, characterization and cell culture studies by Ergin, Ahmet Doğan, Oltulu, Çağatay, Türker, Nebiye Pelin, Demirbolat, Gülen Melike

“…Methotrexate (MTX) is a folic acid antagonist that is widely used to treat osteosarcoma, leukemia, breast cancer, and autoimmune and inflammatory diseases. The…”
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Green biosynthesis, characterization, and cytotoxic effect of magnetic iron nanoparticles using Brassica Oleracea var capitata sub var rubra (red cabbage) aqueous peel extract by Erdoğan, Ömer, Paşa, Salih, Demirbolat, Gülen Melike, Çevik, Özge

“…The green method of nanoparticle synthesis, which is an environment and living-friendly method, is an updated subject that has appeared as an alternative to…”
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DEVELOPMENT OF CHITOSAN MICROPARTICLES FOR CONTROLLED RELEASE OF METOPROLOL TARTARATE by DEMIRBOLAT, Gülen Melike, Yıldız, Cenk, Ergül, Mustafa

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Enginar Yaprağı Sulu Ekstraktı Kullanılarak Çinko Oksit Nanopartiküllerinin Yeşil Sentezi, Karakterizasyonu, Anti-Bakteriyel ve Sitotoksik Etkileri by Ömer ERDOĞAN, Fatih BİRTEKOCAK, Erman ORYAŞIN, Mürüvvet ABBAK, Gülen Melike DEMİRBOLAT, Salih PAŞA, Özge ÇEVİK

“…Amaç: Bu çalışmanın amacı, yeşil kimya yöntemiyle çinko oksit nanopartiküllerini (ZnONPs) sentezlemek ve bu nanopartiküllerin anti-bakteriyel ve anti-kanser…”
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Effect of platelet exosomes loaded with doxorubicin as a targeted therapy on triple-negative breast cancer cells by Uslu, Dilara, Abas, Burcin Irem, Demirbolat, Gulen Melike, Cevik, Ozge

“…Exosomes have come to the fore in drug delivery systems due to their biological-based and immune-suppressing properties. In this study, we investigated the…”
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Long chain fatty acids can form aggregates and affect the membrane integrity by Demirbolat, Gulen Melike, Coskun, Goknil Pelin, Erdogan, Omer, Cevik, Ozge

“…[Display omitted] •Fatty acids can form micelle-like aggregates and cause the disruption of membranes.•The membrane integrity was impaired by fatty acids at a…”
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TRAIL Conjugated Silver Nanoparticle Synthesis, Characterization and Therapeutic Effects on HT-29 Colon Cancer Cells by Birtekocak, Fatih, Demirbolat, Gulen Melike, Cevik, Ozge

“…Colon cancer is one of the most prominent causes of cancer-related morbidity and mortality and curable if detected in the early stages. TNF-related…”
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New Approach to Formulate Methotrexate-Loaded Niosomes: In Vitro Characterization and Cellular Effectiveness by Demirbolat, Gulen Melike, Aktas, Ezgi, Coskun, Goknil Pelin, Erdogan, Omer, Cevik, Ozge

“…Purpose Methotrexate is one of the widely used agents to treat various solid tumors, although its usage brings some challenges because of its poor…”
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Development of a New Drug Delivery System from HELA-Derived Exosomes and the Effect of Docetaxel-Loaded Exosomes on Mitochondrial Apoptosis by Cenik, Melike, Abas, Burcin Irem, Kocabiyik, Bilge, Demirbolat, Gulen Melike, Cevik, Ozge

“…Purpose Exosomes have the potential to create new therapeutics as drug loading carriers. Their important inherent roles are stem from structures (also known…”
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Nanodesigning of multifunctional quantum dots and nanoparticles for the treatment of fibrosarcoma by Demirbolat, Gulen Melike, Altintas, Levent, Yilmaz, Sukran, Arsoy, Taibe, Sözmen, Mahmut, Degim, Ismail Tuncer

“…An effective, dual drug(DD) loaded nanocarrier system (nano particle(NP), quantum dots(QDs)) having two active substances was aimed to develop for the…”
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Lab-on-a-chip system for small extracellular vesicle isolation and drug loading for small extracellular vesicle-mediated drug delivery for treatment of cancer patients by Ozcelik, Adem, Demirbolat, Gulen Melike, Erdogan, Omer, Kozan, Bensu, Akkoyun, Fatih, Cevik, Evrim, Gumus, Erkan, Gul, Irem Bahar, Trabzon, Levent, Cevik, Ozge

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Enginar Yaprağı Sulu Ekstraktı Kullanılarak Çinko Oksit Nanopartiküllerinin Yeşil Sentezi, Karakterizasyonu, Anti-Bakteriyel ve Sitotoksik Etkileri by ERDOĞAN, Ömer, BİRTEKOCAK, Fatih, ORYAŞIN, Erman, ABBAK, Mürüvvet, DEMİRBOLAT, Gülen Melike, PAŞA, Salih, ÇEVİK, Özge

“…Amaç: Bu çalışmanın amacı, yeşil kimya yöntemiyle çinko oksit nanopartiküllerini (ZnONPs) sentezlemek ve bu nanopartiküllerin anti-bakteriyel ve anti-kanser…”
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