Search Results - "Demir, Cansaran Saygili"

Shear stimulation of FOXC1 and FOXC2 differentially regulates cytoskeletal activity during lymphatic valve maturation by Norden, Pieter R, Sabine, Amélie, Wang, Ying, Demir, Cansaran Saygili, Liu, Ting, Petrova, Tatiana V, Kume, Tsutomu

“…Mutations in the transcription factor are predominately associated with lymphedema. Herein, we demonstrate a key role for related factor FOXC1, in addition to…”
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Endothelial Cell Responses to Biomechanical Forces in Lymphatic Vessels by Sabine, Amélie, Saygili Demir, Cansaran, Petrova, Tatiana V

“…Lymphatic vessels are important components of the cardiovascular and immune systems. They contribute both to the maintenance of normal homeostasis and to many…”
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Mechanosensitive mTORC1 signaling maintains lymphatic valves by Saygili Demir, Cansaran, Sabine, Amélie, Gong, Muyun, Dormond, Olivier, Petrova, Tatiana V

“…Homeostatic maintenance and repair of lymphatic vessels are essential for health. We investigated the dynamics and the molecular mechanisms of lymphatic…”
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Dielectric elastomer actuator for mechanical loading of 2D cell cultures by Poulin, Alexandre, Saygili Demir, Cansaran, Rosset, Samuel, Petrova, Tatiana V, Shea, Herbert

“…We demonstrate the use of dielectric elastomer actuators (DEAs) for mechanical stimulation of cells in vitro. The development of living tissues is regulated by…”
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FOXC2 and fluid shear stress stabilize postnatal lymphatic vasculature by Sabine, Amélie, Bovay, Esther, Demir, Cansaran Saygili, Kimura, Wataru, Jaquet, Muriel, Agalarov, Yan, Zangger, Nadine, Scallan, Joshua P, Graber, Werner, Gulpinar, Elgin, Kwak, Brenda R, Mäkinen, Taija, Martinez-Corral, Inés, Ortega, Sagrario, Delorenzi, Mauro, Kiefer, Friedemann, Davis, Michael J, Djonov, Valentin, Miura, Naoyuki, Petrova, Tatiana V

“…Biomechanical forces, such as fluid shear stress, govern multiple aspects of endothelial cell biology. In blood vessels, disturbed flow is associated with…”
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GATA2 is required for lymphatic vessel valve development and maintenance by Kazenwadel, Jan, Betterman, Kelly L, Chong, Chan-Eng, Stokes, Philippa H, Lee, Young K, Secker, Genevieve A, Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M, Sutton, Drew L, Tabruyn, Sebastien P, Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V, Matthews, Jacqueline M, Hahn, Christopher N, Scott, Hamish S, Harvey, Natasha L

“…Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including…”
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Mechanosensitive ACKR4 scavenges CCR7 chemokines to facilitate T cell de-adhesion and passive transport by flow in inflamed afferent lymphatics by Friess, Mona C., Kritikos, Ioannis, Schineis, Philipp, Medina-Sanchez, Jessica Danielly, Gkountidi, Anastasia-Olga, Vallone, Angela, Sigmund, Elena C., Schwitter, Corina, Vranova, Martina, Matti, Christoph, Arasa, Jorge, Saygili Demir, Cansaran, Bovay, Esther, Proulx, Steven T., Tomura, Michio, Rot, Antal, Legler, Daniel F., Petrova, Tatiana V., Halin, Cornelia

“…T cell migration via afferent lymphatics to draining lymph nodes (dLNs) depends on expression of CCR7 in T cells and CCL21 in the lymphatic vasculature. Once…”
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DLL4 promotes continuous adult intestinal lacteal regeneration and dietary fat transport by Bernier-Latmani, Jeremiah, Cisarovsky, Christophe, Demir, Cansaran Saygili, Bruand, Marine, Jaquet, Muriel, Davanture, Suzel, Ragusa, Simone, Siegert, Stefanie, Dormond, Olivier, Benedito, Rui, Radtke, Freddy, Luther, Sanjiv A, Petrova, Tatiana V

“…The small intestine is a dynamic and complex organ that is characterized by constant epithelium turnover and crosstalk among various cell types and the…”
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Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium by Sáinz-Jaspeado, Miguel, Smith, Ross O., Plunde, Oscar, Pawelzik, Sven-Christian, Jin, Yi, Nordling, Sofia, Ding, Yindi, Aspenström, Pontus, Hedlund, Marie, Bastianello, Giulia, Ascione, Flora, Li, Qingsen, Demir, Cansaran Saygili, Fernando, Dinesh, Daniel, Geoffrey, Franco-Cereceda, Anders, Kroon, Jeffrey, Foiani, Marco, Petrova, Tatiana V., Kilimann, Manfred W., Bäck, Magnus, Claesson-Welsh, Lena

“…PALMD (palmdelphin) belongs to the family of paralemmin proteins implicated in cytoskeletal regulation. Single nucleotide polymorphisms in the locus that…”
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Palmdelphin Regulates Nuclear Resilience to Mechanical Stress in the Endothelium by Sáinz-Jaspeado, Miguel, Smith, Ross O., Plunde, Oscar, Pawelzik, Sven-Christian, Jin, Yi, Nordling, Sofia, Ding, Yindi, Aspenström, Pontus, Hedlund, Marie, Bastianello, Giulia, Ascione, Flora, Li, Qingsen, Demir, Cansaran Saygili, Fernando, Dinesh, Daniel, Geoffrey, Franco-Cereceda, Anders, Kroon, Jeffrey, Foiani, Marco, Petrova, Tatiana V., Kilimann, Manfred W., Bäck, Magnus, Claesson-Welsh, Lena

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Cdk5 controls lymphatic vessel development and function by phosphorylation of Foxc2 by Liebl, Johanna, Zhang, Siwei, Moser, Markus, Agalarov, Yan, Demir, Cansaran Saygili, Hager, Bianca, Bibb, James A., Adams, Ralf H., Kiefer, Friedemann, Miura, Naoyuki, Petrova, Tatiana V., Vollmar, Angelika M., Zahler, Stefan

“…The lymphatic system maintains tissue fluid balance, and dysfunction of lymphatic vessels and valves causes human lymphedema syndromes. Yet, our knowledge of…”
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1459 Characterization of tumor budding and the tumor microenvironment in colorectal cancer using hyperplex immunofluorescence by Cansaran Saygili Demir, Gwerder, Mauro, Eroglu, Deniz, Cassano, Marco, Procopio, Maria Giuseppina, Kowal, Joanna, Dupouy, Diego, Zlobec, Inti

“…BackgroundCurrent colon cancer classification, prognostication, and therapy decisions are based mainly on cancer staging.1 2 However, additional biomarkers are…”
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GATA2 is required for lymphatic vessel valve development and maintenance by Kazenwadel, Jan, Betterman, Kelly L, Chong, Chan-Eng, Stokes, Philippa H, Lee, Young K, Secker, Genevieve A, Agalarov, Yan, Demir, Cansaran Saygili, Lawrence, David M, Sutton, Drew L, Tabruyn, Sebastien P, Miura, Naoyuki, Salminen, Marjo, Petrova, Tatiana V, Matthews, Jacqueline M, Hahn, Christopher N, Scott, Hamish S, Harvey, Natasha L

“…Heterozygous germline mutations in the zinc finger transcription factor GATA2 have recently been shown to underlie a range of clinical phenotypes, including…”
Get full text