Search Results - "Demin, Oleg V."

Quantification of Short Term Signaling by the Epidermal Growth Factor Receptor by Kholodenko, Boris N., Demin, Oleg V., Moehren, Gisela, Hoek, Jan B.

“…During the past decade, our knowledge of molecular mechanisms involved in growth factor signaling has proliferated almost explosively. However, the kinetics…”
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Prediction of long-term treatment outcome in HCV following 24 day PEG-IFN alpha-2b therapy using population pharmacokinetic-pharmacodynamic mixture modeling and classification analysis by Vinogradova, Svetlana V., Zhudenkov, Kirill V., Benson, Neil, Van Der Graaf, Piet H., Demin, Oleg V., Karelina, Tatiana A.

“…Mathematical models have been widely used for understanding the dynamics of the hepatitis C virus (HCV). We propose a method to predict final clinical outcome…”
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DBSolve Optimum: a software package for kinetic modeling which allows dynamic visualization of simulation results by Gizzatkulov, Nail M, Goryanin, Igor I, Metelkin, Eugeny A, Mogilevskaya, Ekaterina A, Peskov, Kirill V, Demin, Oleg V

“…Systems biology research and applications require creation, validation, extensive usage of mathematical models and visualization of simulation results by…”
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Modeling of celiac disease immune response and the therapeutic effect of potential drugs by Demin, Oleg O, Smirnov, Sergey V, Sokolov, Victor V, Cucurull-Sanchez, Lourdes, Pichardo-Almarza, Cesar, Flores, M Victoria, Benson, Neil, Demin, Oleg V

“…Celiac disease (CD) is an autoimmune disorder that occurs in genetically predisposed people and is caused by a reaction to the gluten protein found in wheat,…”
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Regulation of leukotriene and 5oxoETE synthesis and the effect of 5-lipoxygenase inhibitors: a mathematical modeling approach by Karelina, Tatiana A, Zhudenkov, Kirill V, Demin, Oleg O, Svetlichny, Dmitry V, Agoram, Balaji, Fairman, David, Demin, Oleg V

“…5-lipoxygenase (5-LO) is a key enzyme in the synthesis of leukotrienes and 5-Oxo-6E,8Z,11Z,14Z-eicosatetraenoic acid (oxoETE). These inflammatory signaling…”
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Control Analysis of Periodic Phenomena in Biological Systems by Kholodenko, Boris N, Demin, Oleg V, Westerhoff, Hans V

“…Principles of the control and regulation of steady-state metabolic systems have been identified in terms of the concepts and laws of metabolic control analysis…”
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Control Analysis of Stationary Forced Oscillations by Demin, Oleg V, Westerhoff, Hans V, Kholodenko, Boris N

“…Metabolic control analysis is here extended to stationary dynamic phenomena arising from a steadily oscillating external force. The extension focuses on the…”
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Cellular kinetic modeling of the microbial metabolism by Goryanin, Igor I, Lebedeva, Galina V, Mogilevskaya, Ekaterina A, Metelkin, Eugeniy A, Demin, Oleg V

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‘Channelled’ pathways can be more sensitive to specific regulatory signals by Kholodenko, Boris N., Demin, Oleg V., Westerhoff, Hans V.

“…In ‘simple’ metabolic pathways the response to an external signal is readily described in terms of the effect of the signal on its receptor enzyme and the…”
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