Search Results - "Demignot, Sylvie"

Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism by Araújo, João R., Tazi, Asmaa, Burlen-Defranoux, Odile, Vichier-Guerre, Sophie, Nigro, Giulia, Licandro, Hélène, Demignot, Sylvie, Sansonetti, Philippe J.

“…Despite the recognized capacity of the gut microbiota to regulate intestinal lipid metabolism, the role of specific commensal species remains undefined. Here,…”
Get full text

Triglyceride-rich lipoproteins and cytosolic lipid droplets in enterocytes: Key players in intestinal physiology and metabolic disorders by Demignot, Sylvie, Beilstein, Frauke, Morel, Etienne

“…During the post-prandial phase, intestinal triglyceride-rich lipoproteins (TRL) i.e. chylomicrons are the main contributors to the serum lipid level, which is…”
Get full text

Proteomic analysis of lipid droplets from Caco-2/TC7 enterocytes identifies novel modulators of lipid secretion by Beilstein, Frauke, Bouchoux, Julien, Rousset, Monique, Demignot, Sylvie

“…In enterocytes, the dynamic accumulation and depletion of triacylglycerol (TAG) in lipid droplets (LD) during fat absorption suggests that cytosolic…”
Get full text

Autophagosomes contribute to intracellular lipid distribution in enterocytes by Khaldoun, Salem Ait, Emond-Boisjoly, Marc-Alexandre, Chateau, Danielle, Carrière, Véronique, Lacasa, Michel, Rousset, Monique, Demignot, Sylvie, Morel, Etienne

“…Enterocytes, the intestinal absorptive cells, have to deal with massive alimentary lipids upon food consumption. They orchestrate complex lipid-trafficking…”
Get full text

Short Term Palmitate Supply Impairs Intestinal Insulin Signaling via Ceramide Production by Tran, Thi Thu Trang, Postal, Bárbara Graziela, Demignot, Sylvie, Ribeiro, Agnès, Osinski, Céline, Pais de Barros, Jean-Paul, Blachnio-Zabielska, Agnieszka, Leturque, Armelle, Rousset, Monique, Ferré, Pascal, Hajduch, Eric, Carrière, Véronique

“…The worldwide prevalence of metabolic diseases is increasing, and there are global recommendations to limit consumption of certain nutrients, especially…”
Get full text

Cholesterol trafficking and raft-like membrane domain composition mediate scavenger receptor class B type 1-dependent lipid sensing in intestinal epithelial cells by Morel, Etienne, Ghezzal, Sara, Lucchi, Géraldine, Truntzer, Caroline, Pais de Barros, Jean-Paul, Simon-Plas, Françoise, Demignot, Sylvie, Mineo, Chieko, Shaul, Philip W., Leturque, Armelle, Rousset, Monique, Carrière, Véronique

“…Scavenger receptor Class B type 1 (SR-B1) is a lipid transporter and sensor. In intestinal epithelial cells, SR-B1-dependent lipid sensing is associated with…”
Get full text

Production of Infectious Hepatitis C Virus in Primary Cultures of Human Adult Hepatocytes by Podevin, Philippe, Carpentier, Arnaud, Pène, Véronique, Aoudjehane, Lynda, Carrière, Matthieu, Zaïdi, Sakina, Hernandez, Céline, Calle, Vanessa, Méritet, Jean–François, Scatton, Olivier, Dreux, Marlène, Cosset, François–Loïc, Wakita, Takaji, Bartenschlager, Ralf, Demignot, Sylvie, Conti, Filoména, Rosenberg, Arielle R, Calmus, Yvon

“…Background & Aims Although hepatitis C virus (HCV) can be grown in the hepatocarcinoma-derived cell line Huh-7, a cell-culture model is needed that supports…”
Get full text

The proteome of cytosolic lipid droplets isolated from differentiated Caco-2/TC7 enterocytes reveals cell-specific characteristics by Bouchoux, Julien, Beilstein, Frauke, Pauquai, Thomas, Guerrera, I. Chiara, Chateau, Danielle, Ly, Nathalie, Alqub, Malik, Klein, Christophe, Chambaz, Jean, Rousset, Monique, Lacorte, Jean-Marc, Morel, Etienne, Demignot, Sylvie

“…Background information. Intestinal absorption of alimentary lipids is a complex process ensured by enterocytes and leading to TRL [TAG (triacylglycerol)‐rich…”
Get full text

Apple procyanidins decrease cholesterol esterification and lipoprotein secretion in Caco-2/TC7 enterocytes by Vidal, Romain, Hernandez-Vallejo, Sandra, Pauquai, Thomas, Texier, Odile, Rousset, Monique, Chambaz, Jean, Demignot, Sylvie, Lacorte, Jean-Marc

“…Decrease of plasma lipid levels by polyphenols was linked to impairment of hepatic lipoprotein secretion. However, the intestine is the first epithelium that…”
Get full text

Lipid micelles stimulate the secretion of triglyceride-enriched apolipoprotein B48-containing lipoproteins by Caco-2 cells by Chateau, Danielle, Pauquai, Thomas, Delers, François, Rousset, Monique, Chambaz, Jean, Demignot, Sylvie

“…Intestinal triglyceride‐rich lipoproteins (TRL) are synthesized from dietary lipids. This study was designed to evaluate the effects of lipid micelles,…”
Get full text

Lipid-dependent bidirectional traffic of apolipoprotein B in polarized enterocytes by Morel, Etienne, Demignot, Sylvie, Chateau, Danielle, Chambaz, Jean, Rousset, Monique, Delers, François

“…Enterocytes are highly polarized cells that transfer nutrients across the intestinal epithelium from the apical to the basolateral pole. Apolipoprotein B…”
Get full text

Cellular evaluation of superoxide dismutase mimics as catalytic drugs: Challenges and opportunities by Schanne, Gabrielle, Demignot, Sylvie, Policar, Clotilde, Delsuc, Nicolas

“…•Superoxide dismutases mimics (SOD mimics) are catalytic drugs that decrease oxidative stress.•Cellular models for evaluation of SOD mimics are comprehensively…”
Get full text

Lipids, from molecular mechanisms to diseases by Dugail, Isabelle, Demignot, Sylvie, Touqui, Lhousseine, Thiam, Abdou Rachid

Get full text

Jejunum: The understudied meeting place of dietary lipids and the microbiota by Lema, Ingrid, Araújo, João Ricardo, Rolhion, Nathalie, Demignot, Sylvie

“…Although the jejunum is the main intestinal compartment responsible for lipid digestion and absorption, most of the studies assessing the impact of dietary…”
Get full text

Characteristics and functions of lipid droplets and associated proteins in enterocytes by Beilstein, Frauke, Carrière, Véronique, Leturque, Armelle, Demignot, Sylvie

“…Cytosolic lipid droplets (LDs) are observed in enterocytes of jejunum during lipid absorption. One important function of the intestine is to secrete…”
Get full text

Jejunum: The understudied meeting place of dietary lipids and the microbiota by Lema, Ingrid, Araújo, João Ricardo, Rolhion, Nathalie, Demignot, Sylvie

Get full text

Lysophosphatidylcholine acyltransferase 1 is downregulated by hepatitis C virus: impact on production of lipo-viro-particles by Beilstein, Frauke, Lemasson, Matthieu, Pène, Véronique, Rainteau, Dominique, Demignot, Sylvie, Rosenberg, Arielle R

“…HCV is intimately linked with the liver lipid metabolism, devoted to the efflux of triacylglycerols stored in lipid droplets (LDs) in the form of…”
Get more information

Inertness of Superoxide Dismutase Mimics Mn(II) Complexes Based on an Open-Chain Ligand, Bioactivity, and Detection in Intestinal Epithelial Cells by Schanne, Gabrielle, Zoumpoulaki, Martha, Gazzah, Géraldine, Vincent, Amandine, Preud’homme, Hugues, Lobinski, Ryszard, Demignot, Sylvie, Seksik, Philippe, Delsuc, Nicolas, Policar, Clotilde

“…Oxidative stress is known to play a major role in the pathogenesis of inflammatory bowel diseases (IBDs), and, in particular, superoxide dismutase (SODs)…”
Get full text

Fermentation Products of Commensal Bacteria Alter Enterocyte Lipid Metabolism by Araújo, João, Tazi, Asmaa, Burlen-Defranoux, Odile, Vichier-Guerre, Sophie, Nigro, Giulia S, Licandro, Hélène, Demignot, Sylvie, Sansonetti, Philippe

“…Despite the recognized capacity of the gut microbiota to regulate intestinal lipid metabolism, the role of specific commensal species remains undefined. Here,…”
Get full text

Transglutaminase activity in rabbit articular chondrocytes in culture by Demignot, Sylvie, Borge, Laurence, Adolphe, Monique

“…In vivo, articular chondrocytes produce an important amount of extracellular matrix (cartilage) whose quality is impaired upon inflammation or aging leading to…”
Get full text