Search Results - "Demgenski, Janine"

Inhibitor of Apoptosis Protein-1 Regulates Tumor Necrosis Factor−Mediated Destruction of Intestinal Epithelial Cells by Grabinger, Thomas, Bode, Konstantin J, Demgenski, Janine, Seitz, Carina, Delgado, M. Eugenia, Kostadinova, Feodora, Reinhold, Cindy, Etemadi, Nima, Wilhelm, Sabine, Schweinlin, Matthias, Hänggi, Kay, Knop, Janin, Hauck, Christof, Walles, Heike, Silke, John, Wajant, Harald, Nachbur, Ueli, W. Wei-Lynn, Wong, Brunner, Thomas

“…Background and Aims Tumor necrosis factor (TNF) is a cytokine that promotes inflammation and contributes to pathogenesis of inflammatory bowel diseases. Unlike…”
Get full text

Death Receptor Interactions With the Mitochondrial Cell Death Pathway During Immune Cell-, Drug- and Toxin-Induced Liver Damage by Spinnenhirn, Valentina, Demgenski, Janine, Brunner, Thomas

“…Due to its extensive vascularization and physiological function as a filter and storage organ, the liver is constantly exposed to infectious and tumorigenic…”
Get full text

Analyzing structure-function relationships of artificial and cancer-associated PARP1 variants by reconstituting TALEN-generated HeLa PARP1 knock-out cells by Rank, Lisa, Veith, Sebastian, Gwosch, Eva C, Demgenski, Janine, Ganz, Magdalena, Jongmans, Marjolijn C, Vogel, Christopher, Fischbach, Arthur, Buerger, Stefanie, Fischer, Jan M F, Zubel, Tabea, Stier, Anna, Renner, Christina, Schmalz, Michael, Beneke, Sascha, Groettrup, Marcus, Kuiper, Roland P, Bürkle, Alexander, Ferrando-May, Elisa, Mangerich, Aswin

“…Genotoxic stress activates PARP1, resulting in the post-translational modification of proteins with poly(ADP-ribose) (PAR). We genetically deleted PARP1 in one…”
Get full text