Search Results - "Demetris, Jake"

Liver-Specific Deletion of Augmenter of Liver Regeneration Accelerates Development of Steatohepatitis and Hepatocellular Carcinoma in Mice by Gandhi, Chandrashekhar R, Chaillet, J. Richard, Nalesnik, Michael A, Kumar, Sudhir, Dangi, Anil, Demetris, A. Jake, Ferrell, Robert, Wu, Tong, Divanovic, Senad, Stankeiwicz, Traci, Shaffer, Benjamin, Stolz, Donna B, Harvey, Stephen A.K, Wang, Jiang, Starzl, Thomas E

“…Background & Aims Augmenter of liver regeneration (ALR, encoded by GFER ) is a widely distributed pleiotropic protein originally identified as a hepatic growth…”
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Long‐term outcome of human leukocyte antigen mismatching in liver transplantation: Results of the national institute of diabetes and digestive and kidney diseases liver transplantation database by Balan, Vijayan, Ruppert, Kris, Demetris, A. Jake, Ledneva, Tatiana, Duquesnoy, Rene J., Detre, Katherine M., Wei, Yuling L., Rakela, Jorge, Schafer, Daniel F., Roberts, John P., Everhart, James E., Wiesner, Russell H.

“…A perfect or nearly perfect human leukocyte antigen (HLA) match has been associated with better immediate and long‐term survival of diseased donor kidney…”
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IL-33-mediated IL-13 secretion by ST2+ Tregs controls inflammation after lung injury by Liu, Quan, Dwyer, Gaelen K, Zhao, Yifei, Li, Huihua, Mathews, Lisa R, Chakka, Anish Bhaswanth, Chandran, Uma R, Demetris, Jake A, Alcorn, John F, Robinson, Keven M, Ortiz, Luis A, Pitt, Bruce R, Thomson, Angus W, Fan, Ming-Hui, Billiar, Timothy R, Turnquist, Hēth R

“…Acute respiratory distress syndrome is an often fatal disease that develops after acute lung injury and trauma. How released tissue damage signals, or…”
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Cyclooxygenase-2 promotes hepatocellular carcinoma cell growth through Akt activation: Evidence for Akt inhibition in celecoxib-induced apoptosis by Leng, Jing, Han, Chang, Demetris, A.Jake, Michalopoulos, George K., Wu, Tong

“…Cyclooxygenase-2 (COX-2)-controlled prostaglandin (PG) metabolism recently has been implicated in the pathogenesis of hepatocellular carcinoma (HCC). However,…”
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A schema for histologic grading of small intestine allograft acute rejection by TONG WU, ABU-ELMAGD, Kareem, BOND, Geoffy, NALESNIK, Michael A, RANDHAWA, Parmjeet, DEMETRIS, A. Jake

“…Histologic evaluation of small bowel allograft biopsies is important for the diagnosis of acute rejection. However, a standard histologic schema to grade the…”
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The prevalence and natural history of untreated isolated central perivenulitis in adult allograft livers by Krasinskas, Alyssa M., Demetris, A. Jake, Poterucha, John J., Abraham, Susan C.

“…Central perivenulitis (CP) in the allograft liver can be associated with portal‐based acute cellular rejection and autoimmune hepatitis or can occur in…”
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Acute hepatic allograft rejection: Incidence, risk factors, and impact on outcome by Wiesner, Russell H., Demetris, A. Jake, Belle, Steven H., Seaberg, Eric C., Lake, John R., Zetterman, Rowen K., Everhart, James, Detre, Katherine M.

“…Hepatic allograft rejection remains an important problem following liver transplantation, and, indeed, complications related to the administration of…”
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Distinguishing between recurrent primary sclerosing cholangitis and chronic rejection by Demetris, Anthony Jake

“…Key Concepts: 1 Recurrent primary sclerosing cholangitis (PSC) is extremely difficult, if not impossible, to distinguish from other causes of biliary…”
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Banff consensus recommendations for steatosis assessment in donor livers by Neil, Desley A. H., Minervini, Marta, Smith, Maxwell L., Hubscher, Stefan G., Brunt, Elizabeth M., Demetris, A. Jake

“…Background and Aims No consensus criteria or approaches exist regarding assessment of steatosis in the setting of human donor liver suitability for…”
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Effect of liver transplantation on inflammatory bowel disease in patients with primary sclerosing cholangitis by Dvorchik, Igor, Subotin, Michael, Demetris, A.Jake, Fung, John J., Starzl, Thomas E., Wieand, Samuel, Abu-Elmagd, Kareem M.

“…This report investigates the influence of liver transplantation and concomitant immunosuppression on the course of progression of inflammatory bowel disease…”
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Reply "additional viewpoints from transplant surgeons on Banff consensus recommendations for the assessment of steatotic donor livers" by Neil, Desley Ah, Smith, Maxwell L, Minervini, Marta, Demetris, A Jake

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A pilot study of interferon alfa and ribavirin combination in liver transplant recipients with recurrent hepatitis C by Shakil, A.Obaid, McGuire, Brendon, Crippin, Jeff, Teperman, Lewis, Demetris, A.Jake, Conjeevaram, Hari, Gish, Robert, Kwo, Paul, Balan, Vijayan, Wright, Teresa L., Brass, Clifford, Rakela, Jorge

“…Although interferon alfa (IFN-α) and ribavirin are widely used in the treatment of hepatitis C, their role in the transplant recipient is unclear. We conducted…”
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Porcine partial liver transplantation: A novel model of the “small‐for‐size” liver graft by Kelly, Dympna M., Demetris, A. Jake, Fung, John J., Marcos, Amadeo, Zhu, Yue, Subbotin, Vladimir, Yin, Lu, Totsuka, Eishi, Ishii, Tomohiro, Lee, Ming C., Gutierrez, Jorge, Costa, Guilherme, Venkataraman, Raman, Madariaga, Juan R.

“…Increasing shortage of cadaveric grafts demands the utilization of living donor and split liver grafts. The purpose of this study was to 1) define the…”
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Next-generation pathology detection of T cell-antigen-presenting cell immune synapses in human liver allografts by Wood-Trageser, Michelle A, Lesniak, Drew, Gambella, Alessandro, Golnoski, Kayla, Feng, Sandy, Bucuvalas, John, Sanchez-Fueyo, Alberto, Demetris, A Jake

“…In otherwise near-normal appearing biopsies by routine light microscopy, next-generation pathology (NGP) detected close pairings (immune pairs; iPAIRs) between…”
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The cyclooxygenase-2 inhibitor celecoxib blocks phosphorylation of Akt and induces apoptosis in human cholangiocarcinoma cells by Wu, Tong, Leng, Jing, Han, Chang, Demetris, Anthony Jake

“…The expression of cyclooxygenase (COX)-2 is increased in human cancers including cholangiocarcinoma. This study was designed to evaluate the effect and…”
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IL-33 expands suppressive CD11b+ Gr-1(int) and regulatory T cells, including ST2L+ Foxp3+ cells, and mediates regulatory T cell-dependent promotion of cardiac allograft survival by Turnquist, Heth R, Zhao, Zhenlin, Rosborough, Brian R, Liu, Quan, Castellaneta, Antonino, Isse, Kumiko, Wang, Zhiliang, Lang, Megan, Stolz, Donna Beer, Zheng, Xin Xiao, Demetris, A Jake, Liew, Foo Y, Wood, Kathryn J, Thomson, Angus W

“…IL-33 administration is associated with facilitation of Th2 responses and cardioprotective properties in rodent models. However, in heart transplantation, the…”
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Evidence for Alloimmune Sinusoidal Injury in De Novo Nodular Regenerative Hyperplasia After Liver Transplantation by Sebagh, Mylène, Yilmaz, Funda, Kounis, Ilias, Saliba, Faouzi, Feray, Cyrille, Taupin, Jean-Luc, Cherqui, Daniel, Azoulay, Daniel, Samuel, Didier, Coilly, Audrey, Demetris, Antony-Jake, Neil, Desley

“…Posttransplant nodular regenerative hyperplasia (NRH) mostly remains unexplained. Microvascular injury due to antibody-mediated rejection (AMR) is suspected,…”
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Fibroinflammatory Biliary Stricture: A Rare Bile Duct Lesion Masquerading as Cholangiocarcinoma by Gamblin, T. Clark, Krasinskas, A. M., Slivka, A. S., Tublin, M. E., Demetris, Jake, Shue, Eveline, Caro, Susan, Marsh, J. Wallis, James Moser, A.

“…Introduction Fibroinflammatory biliary stricture (FIBS) is a rare benign tumor-like process of the extrahepatic bile duct that masquerades as…”
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Involvement of 85‐kd cytosolic phospholipase A2 and cyclooxygenase‐2 in the proliferation of human cholangiocarcinoma cells by Wu, Tong, Han, Chang, Lunz, John G., Michalopoulos, George, Shelhamer, James H., Demetris, A. Jake

“…Cyclooxygenase 2 (COX‐2) and cytosolic phospholipase A2 (cPLA2) are the crucial rate‐limiting enzymes in prostaglandin (PG) metabolism that show increased…”
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Hepatic antigen-presenting cells and regulation of liver transplant outcome by Thomson, Angus W., Geller, David A., Gandhi, Chandrashekhar, Murase, Noriko, Demetris, A. Jake, Beer-Stolz, Donna

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