Search Results - "Demetris, A. J."

Banff 2011 Meeting Report: New Concepts in Antibody‐Mediated Rejection by Mengel, M., Sis, B., Haas, M., Colvin, R. B., Halloran, P. F., Racusen, L. C., Solez, K., Cendales, L., Demetris, A. J., Drachenberg, C. B., Farver, C. F., Rodriguez, E. R., Wallace, W. D., Glotz, D.

“…The 11th Banff meeting was held in Paris, France, from June 5 to 10, 2011, with a focus on refining diagnostic criteria for antibody‐mediated rejection (ABMR)…”
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Liver Transplantation Using Donation After Cardiac Death Donors: Long‐Term Follow‐Up from a Single Center by De Vera, M. E., Lopez‐Solis, R., Dvorchik, I., Campos, S., Morris, W., Demetris, A. J., Fontes, P., Marsh, J. W.

“…There is a lack of universally accepted clinical parameters to guide the utilization of donation after cardiac death (DCD) donor livers and it is unclear as to…”
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The Role of Donor‐Specific HLA Alloantibodies in Liver Transplantation by O'Leary, J. G., Demetris, A. J., Friedman, L. S., Gebel, H. M., Halloran, P. F., Kirk, A. D., Knechtle, S. J., McDiarmid, S. V., Shaked, A., Terasaki, P. I., Tinckam, K. J., Tomlanovich, S. J., Wood, K. J., Woodle, E. S., Zachary, A. A., Klintmalm, G. B.

“…The impact of donor‐specific HLA alloantibodies (DSA) on short‐ and long‐term liver transplant outcome is not clearly defined. While it is clear that not all…”
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Surgically-induced weight loss significantly improves nonalcoholic fatty liver disease and the metabolic syndrome by Mattar, Samer G, Velcu, Laura M, Rabinovitz, Mordechai, Demetris, A J, Krasinskas, A M, Barinas-Mitchell, Emma, Eid, George M, Ramanathan, Ramesh, Taylor, Debra S, Schauer, Philip R

“…To evaluate the effects of surgical weight loss on fatty liver disease in severely obese patients. Nonalcoholic fatty liver disease (NAFLD), a spectrum that…”
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Regulatory Dendritic Cell Infusion Prolongs Kidney Allograft Survival in Nonhuman Primates by Ezzelarab, M. B., Zahorchak, A. F., Lu, L., Morelli, A. E., Chalasani, G., Demetris, A. J., Lakkis, F. G., Wijkstrom, M., Murase, N., Humar, A., Shapiro, R., Cooper, D. K. C., Thomson, A. W.

“…We examined the influence of regulatory dendritic cells (DCreg), generated from cytokine‐mobilized donor blood monocytes in vitamin D3 and IL‐10, on renal…”
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Perforin inhibition protects from lethal endothelial damage during fulminant viral hepatitis by Welz, M., Eickhoff, S., Abdullah, Z., Trebicka, J., Gartlan, K. H., Spicer, J. A., Demetris, A. J., Akhlaghi, H., Anton, M., Manske, K., Zehn, D., Nieswandt, B., Kurts, C., Trapani, J. A., Knolle, P., Wohlleber, D., Kastenmüller, W.

“…CD8 T cells protect the liver against viral infection, but can also cause severe liver damage that may even lead to organ failure. Given the lack of…”
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“Plasma Cell Hepatitis” in Liver Allografts: Identification and Characterization of an IgG4‐Rich Cohort by Castillo‐Rama, M., Sebagh, M., Sasatomi, E., Randhawa, P., Isse, K., Salgarkar, A. D., Ruppert, K., Humar, A., Demetris, A. J.

“…Plasma cell hepatitis (PCH), also known as “de novo autoimmune” hepatitis, is an increasingly recognized, but suboptimally named and poorly understood,…”
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Digital Transplantation Pathology: Combining Whole Slide Imaging, Multiplex Staining and Automated Image Analysis by Isse, K., Lesniak, A., Grama, K., Roysam, B., Minervini, M. I., Demetris, A. J.

“…Conventional histopathology is the gold standard for allograft monitoring, but its value proposition is increasingly questioned. “‐Omics” analysis of tissues,…”
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Banff '05 Meeting Report: Differential Diagnosis of Chronic Allograft Injury and Elimination of Chronic Allograft Nephropathy (‘CAN’) by Solez, K., Colvin, R. B., Racusen, L. C., Sis, B., Halloran, P. F., Birk, P. E., Campbell, P. M., Cascalho, M., Collins, A. B., Demetris, A. J., Drachenberg, C. B., Gibson, I. W., Grimm, P. C., Haas, M., Lerut, E., Liapis, H., Mannon, R. B., Marcus, P. B., Mengel, M., Mihatsch, M. J., Nankivell, B. J., Nickeleit, V., Papadimitriou, J. C., Platt, J. L., Randhawa, P., Roberts, I., Salinas‐Madriga, L., Salomon, D. R., Seron, D., Sheaff, M., Weening, J. J.

“…The 8th Banff Conference on Allograft Pathology was held in Edmonton, Canada, 15–21 July 2005. Major outcomes included the elimination of the non‐specific term…”
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Re‐examination of the Lymphocytotoxic Crossmatch in Liver Transplantation: Can C4d Stains Help in Monitoring? by Lunz, J., Ruppert, K. M., Cajaiba, M. M., Isse, K., Bentlejewski, C. A., Minervini, M., Nalesnik, M. A., Randhawa, P., Rubin, E., Sasatomi, E., Vera, M. E. de, Fontes, P., Humar, A., Zeevi, A., Demetris, A. J.

“…C4d‐assisted recognition of antibody‐mediated rejection (AMR) in formalin‐fixed paraffin‐embedded tissues (FFPE) from donor‐specific antibody‐positive (DSA+)…”
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Biliary wound healing, ductular reactions, and IL-6/gp130 signaling in the development of liver disease by Demetris, A-J, Lunz, 3rd, John-G, Specht, Susan, Nozaki, Isao

“…Basic and translational wound healing research in the biliary tree lag significantly behind similar studies on the skin and gastrointestinal tract. This is at…”
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Multiphoton Intravital Microscopy of the Transplanted Mouse Kidney by Camirand, G., Li, Q., Demetris, A. J., Watkins, S. C., Shlomchik, W. D., Rothstein, D. M., Lakkis, F. G.

“…Graft outcomes after kidney transplantation continue to be adversely affected by ischemia‐reperfusion injury and rejection. High‐resolution, real‐time imaging…”
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Recurrent hepatitis C in liver allografts: Prospective assessment of diagnostic accuracy, identification of pitfalls, and observations about pathogenesis by DEMETRIS, A. J, EGHTESAD, B, SHAKIL, A. O, MURASE, N, FUNG, J. J, STARZL, T. E, MARCOS, A, RUPPERT, K, NALESNIK, M. A, RANDHAWA, P, WU, T, KRASINSKAS, A, FONTES, P, CACCIARELLI, T

“…The accuracy of a prospective histopathologic diagnosis of rejection and recurrent hepatitis C (HCV) was determined in 48 HCV RNA-positive liver allograft…”
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Allograft Outcomes in Outbred Mice by Reichenbach, D. K., Li, Q., Hoffman, R. A., Williams, A. L., Shlomchik, W. D., Rothstein, D. M., Demetris, A. J., Lakkis, F. G.

“…Inbreeding depression and lack of genetic diversity in inbred mice could mask unappreciated causes of graft failure or remove barriers to tolerance induction…”
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Human polyoma virus-associated interstitial nephritis in the allograft kidney by RANDHAWA, P. S, FINKELSTEIN, S, SCANTLEBURY, V, SHAPIRO, R, VIVAS, C, JORDAN, M, PICKEN, M. M, DEMETRIS, A. J

“…Asymptomatic polyoma virus infection documented by urine cytology or serology is well known, but the clinical course of biopsy-proven interstitial nephritis is…”
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Cell migration, chimerism, and graft acceptance by Starzl, T E, Demetris, A J, Murase, N, Ildstad, S, Ricordi, C, Trucco, M

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Nephropathy Due to Polyomavirus Type BK by Randhawa, Parmjeet S, Demetris, Anthony J

“…Polyomavirus type BK (BK virus) is a nonenveloped virus with circular, double-stranded DNA that has 70 percent homology with simian virus 40. It was first…”
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Dilated Cardiomyopathy in Transgenic Mice With Cardiac-Specific Overexpression of Tumor Necrosis Factor-alpha by Kubota, Toru, McTiernan, Charles F, Frye, Carole S, Slawson, Susan E, Lemster, Bonnie H, Koretsky, Alan P, Demetris, A. Jake, Feldman, Arthur M

“…The failing human heart expresses tumor necrosis factor-alpha (TNF-alpha). However, its pathophysiological significance is not clear. We previously reported…”
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Acute hepatic allograft rejection: Incidence, risk factors, and impact on outcome by Wiesner, Russell H., Demetris, A. Jake, Belle, Steven H., Seaberg, Eric C., Lake, John R., Zetterman, Rowen K., Everhart, James, Detre, Katherine M.

“…Hepatic allograft rejection remains an important problem following liver transplantation, and, indeed, complications related to the administration of…”
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Functional Immune Anatomy of the Liver—As an Allograft by Demetris, A. J., Bellamy, C. O. C., Gandhi, C. R., Prost, S., Nakanuma, Y., Stolz, D. B.

“…The liver is an immunoregulatory organ in which a tolerogenic microenvironment mitigates the relative “strength” of local immune responses. Paradoxically,…”
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