Search Results - "Demestichas, Breanna"

Proactive and reactive roles of TGF-β in cancer by Kuburich, Nick A, Sabapathy, Thiru, Demestichas, Breanna R, Maddela, Joanna Joyce, den Hollander, Petra, Mani, Sendurai A

“…Cancer cells adapt to varying stress conditions to survive through plasticity. Stem cells exhibit a high degree of plasticity, allowing them to generate more…”
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Oral famotidine versus placebo in non-hospitalised patients with COVID-19: a randomised, double-blind, data-intense, phase 2 clinical trial by Brennan, Christina M, Nadella, Sandeep, Zhao, Xiang, Dima, Richard J, Jordan-Martin, Nicole, Demestichas, Breanna R, Kleeman, Sam O, Ferrer, Miriam, von Gablenz, Eva Carlotta, Mourikis, Nicholas, Rubin, Michael E, Adnani, Harsha, Lee, Hassal, Ha, Taehoon, Prum, Soma, Schleicher, Cheryl B, Fox, Sharon S, Ryan, Michael G, Pili, Christina, Goldberg, Gary, Crawford, James M, Goodwin, Sara, Zhang, Xiaoyue, Preall, Jonathan B, Costa, Ana S H, Conigliaro, Joseph, Masci, Joseph R, Yang, Jie, Tuveson, David A, Tracey, Kevin J, Janowitz, Tobias

“…We assessed whether famotidine improved inflammation and symptomatic recovery in outpatients with mild to moderate COVID-19. Randomised, double-blind,…”
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Expanding the Versatility of Microbial Transglutaminase Using α‐Effect Nucleophiles as Noncanonical Substrates by Chio, Tak Ian, Demestichas, Breanna R., Brems, Brittany M., Bane, Susan L., Tumey, L. Nathan

“…The substrate promiscuity of microbial transglutaminase (mTG) has been exploited in various applications in biotechnology, in particular for the attachment of…”
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Stabilizing vimentin phosphorylation inhibits stem-like cell properties and metastasis of hybrid epithelial/mesenchymal carcinomas by Kuburich, Nick A., den Hollander, Petra, Castaneda, Maria, Pietilä, Mika, Tang, Ximing, Batra, Harsh, Martínez-Peña, Francisco, Visal, Tanvi H., Zhou, Tieling, Demestichas, Breanna R., Dontula, Ritesh V., Liu, Jojo Y., Maddela, Joanna Joyce, Padmanabhan, Reethi S., Phi, Lan Thi Hanh, Rosolen, Matthew J., Sabapathy, Thiru, Kumar, Dhiraj, Giancotti, Filippo G., Lairson, Luke L., Raso, Maria Gabriela, Soundararajan, Rama, Mani, Sendurai A.

“…Epithelial-mesenchymal transition (EMT) empowers epithelial cells with mesenchymal and stem-like attributes, facilitating metastasis, a leading cause of…”
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Sensitive, non-immunogenic in vivo imaging of cancer metastases and immunotherapy response by Merrill, Joseph R, Inguscio, Alessandra, Chung, Taemoon, Demestichas, Breanna, Garcia, Libia A, Habel, Jill, Lewis, David Y, Janowitz, Tobias, Lyons, Scott K

“…Non-invasive imaging of tumors expressing reporter transgenes is a popular preclinical method for studying tumor development and response to therapy due to its…”
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Expanding the Versatility of Microbial Transglutaminase Using α‐Effect Nucleophiles as Noncanonical Substrates by Chio, Tak Ian, Demestichas, Breanna R., Brems, Brittany M., Bane, Susan L., Tumey, L. Nathan

“…The substrate promiscuity of microbial transglutaminase (mTG) has been exploited in various applications in biotechnology, in particular for the attachment of…”
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Abstract 5672: Comparative mouse pharmacokinetics of matched- and unmatched-isotype anti-PD-L1 antibodies by Demestichas, Breanna, Kleeman, Sam, Chvasta, Matthew, Janowitz, Tobias

“…Abstract Immune checkpoint inhibitors (ICI) are highly effective for a minority of patients with cancer. Pre-clinical research into mechanisms of ICI…”
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Abstract 5451: FOXC2 influences EMT-induced stem cell properties through regulation of FABP4 in breast cancer by Demestichas, Breanna R., Shivakumar, Vinita, Ramirez-Peña, Esmeralda, Taube, Joseph, Hollander, Petra den, Mani, Sendurai A.

“…Abstract Cancer stem cells (CSCs) pose a significant clinical challenge due to their inherent resistance to therapies and prevalence in cancer recurrence. CSCs…”
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Abstract 2891: Cystatin C is glucocorticoid-responsive, directs recruitment of Trem2+ macrophages and predicts failure of cancer immunotherapy by Kleeman, Sam O., Demestichas, Breanna, Mourikis, Nicholas, Ferrer, Miriam, Gao, Qing, Loiero, Dominik, Riazat-Kesh, Yosef J., Bankier, Sean, Chantzichristos, Dimitrios, Johannsson, Gudmundur, Regan, Claire, Preall, Jonathan, Koelzer, Viktor H., Walker, Brian R., Meyer, Hannah, Janowitz, Tobias

“…Abstract Cystatin C (CyC) is a secreted cysteine protease inhibitor that is commonly used as a marker of renal function, and whose biological functions remain…”
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Cystatin C is glucocorticoid responsive, directs recruitment of Trem2+ macrophages, and predicts failure of cancer immunotherapy by Kleeman, Sam O, Thakir, Tuba Mansoor, Demestichas, Breanna, Mourikis, Nicholas, Loiero, Dominik, Ferrer, Miriam, Bankier, Sean, Riazat-Kesh, Yosef J R A, Lee, Hassal, Chantzichristos, Dimitrios, Regan, Claire, Preall, Jonathan, Sinha, Sarthak, Rosin, Nicole, Yipp, Bryan, de Almeida, Luiz G N, Biernaskie, Jeff, Dufour, Antoine, Tober-Lau, Pinkus, Ruusalepp, Arno, Bjorkegren, Johan L M, Ralser, Markus, Kurth, Florian, Demichev, Vadim, Heywood, Todd, Gao, Qing, Johannsson, Gudmundur, Koelzer, Viktor H, Walker, Brian R, Meyer, Hannah V, Janowitz, Tobias

“…Cystatin C (CyC), a secreted cysteine protease inhibitor, has unclear biological functions. Many patients exhibit elevated plasma CyC levels, particularly…”
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