Oseltamivir for prophylaxis of influenza in vaccinated hemodialysis patients

To the Editor—Influenza is a seasonal respiratory orthomyxoviral infection that causes major morbidity and mortality in elderly and patients with chronic conditions such as end-stage renal disease. Serological studies indicate an impaired immune response in hemodialysis patients to influenza vaccina...

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Bibliographic Details
Published in:	Infection control and hospital epidemiology Vol. 40; no. 4; pp. 497 - 498
Main Authors:	Van Praet, Jens T, Steyaert, Sanne, Demesmaecker, Mirjam, Grootaert, Veerle, Reynders, Marijke
Format:	Journal Article
Language:	English
Published:	United States Cambridge University Press 01-04-2019
Subjects:	Antiviral Agents - administration & dosage Belgium - epidemiology Disease prevention Epidemics Hemodialysis Humans Immune response Influenza Influenza, Human - epidemiology Influenza, Human - prevention & control Mortality Nursing Oseltamivir - administration & dosage Pharmacokinetics Pre-Exposure Prophylaxis - methods Program Evaluation Prophylaxis Renal Dialysis Vaccines Viral Vaccines Belgium
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Summary:	To the Editor—Influenza is a seasonal respiratory orthomyxoviral infection that causes major morbidity and mortality in elderly and patients with chronic conditions such as end-stage renal disease. Serological studies indicate an impaired immune response in hemodialysis patients to influenza vaccination, even after a booster vaccine dose, and its real effect on clinical outcomes and mortality is uncertain.2,3 Oseltamivir is a neuramidase inhibitor licensed for the treatment of and prophylaxis for influenza. [...]5 new infections occurred in week 8 (Figure 1).
Bibliography:	SourceType-Other Sources-1 content type line 63 ObjectType-Correspondence-1 ObjectType-Undefined-2
ISSN:	0899-823X 1559-6834
DOI:	10.1017/ice.2019.11