Search Results - "Dementyeva, Elena V"
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Studying Pathogenetic Contribution of a Variant of Unknown Significance, p.M659I (c.1977G > A) in MYH7, to the Development of Hypertrophic Cardiomyopathy Using CRISPR/Cas9-Engineered Isogenic Induced Pluripotent Stem Cells
Published in International journal of molecular sciences (09-08-2024)“…Hypertrophic cardiomyopathy (HCM) is a cardiovascular pathology that is caused by variants in genes encoding sarcomere-associated proteins. However, the…”
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Dynamics of the two heterochromatin types during imprinted X chromosome inactivation in vole Microtus levis
Published in PloS one (04-02-2014)“…In rodent female mammals, there are two forms of X-inactivation - imprinted and random which take place in extraembryonic and embryonic tissues, respectively…”
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Human Induced Pluripotent Stem Cell-Derived Cardiomyocytes Afford New Opportunities in Inherited Cardiovascular Disease Modeling
Published in Cardiology research and practice (01-01-2016)“…Fundamental studies of molecular and cellular mechanisms of cardiovascular disease pathogenesis are required to create more effective and safer methods of…”
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Mosaic heterochromatin of the inactive X chromosome in vole Microtus rossiaemeridionalis
Published in Mammalian genome (01-10-2009)“…During early development in female mammals, one of the two X chromosomes recruits a variety of protein complexes that establish repressive chromatin…”
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A regulatory potential of the Xist gene promoter in vole M. rossiaemeridionalis
Published in PloS one (11-05-2012)“…X chromosome inactivation takes place in the early development of female mammals and depends on the Xist gene expression. The mechanisms of Xist expression…”
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Diverse developmental strategies of X chromosome dosage compensation in eutherian mammals
Published in The International journal of developmental biology (2019)“…In eutherian mammals, dosage compensation arose to balance X-linked gene expression between sexes and relatively to autosomal gene expression in the evolution…”
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Impact of Xist RNA on chromatin modifications and transcriptional silencing maintenance at different stages of imprinted X chromosome inactivation in vole Microtus levis
Published in Chromosoma (01-03-2018)“…In vole Microtus levis , cells of preimplantation embryo and extraembryonic tissues undergo imprinted X chromosome inactivation (iXCI) which is triggered by a…”
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Human induced pluripotent stem cells derived from fetal neural stem cells successfully undergo directed differentiation into cartilage
Published in Stem cells and development (01-06-2011)“…Induced pluripotent stem (iPS) cells can be derived from a wide range of somatic cells via overexpression of a set of specific genes. With respect to their…”
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X-chromosome upregulation and inactivation: two sides of the dosage compensation mechanism in mammals
Published in BioEssays (2009)“…Mammals have a very complex, tightly controlled, and developmentally regulated process of dosage compensation. One form of the process equalizes expression of…”
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Difference between random and imprinted X inactivation in common voles
Published in Chromosoma (01-10-2010)“…During early development in female mammals, most genes on one of the two X-chromosomes undergo transcriptional silencing. In the extraembryonic lineages of…”
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Dynamics of the Two Heterochromatin Types during Imprinted X Chromosome Inactivation in Vole Microtus levis: e88256
Published in PloS one (01-02-2014)“…In rodent female mammals, there are two forms of X-inactivation - imprinted and random which take place in extraembryonic and embryonic tissues, respectively…”
Get full text
Journal Article