Search Results - "Demchuk, Oleg M."
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New Perspectives for Fisetin
Published in Frontiers in chemistry (30-10-2019)“…Fisetin is a flavonol that shares distinct antioxidant properties with a plethora of other plant polyphenols. Additionally, it exhibits a specific biological…”
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Fluconazole Analogs and Derivatives: An Overview of Synthesis, Chemical Transformations, and Biological Activity
Published in Molecules (Basel, Switzerland) (01-06-2024)“…Fluconazole (2-(2,4-difluorophenyl)-1,3-bis(1 -1,2,4-triazol-1-yl)propan-2-ol), which was patented in 1981 and introduced for commercial use in 1988, is a…”
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Arylcyanomethylenequinone Oximes: An Overview of Synthesis, Chemical Transformations, and Biological Activity
Published in Molecules (Basel, Switzerland) (01-07-2023)“…Quinone methides are a class of biologically active compounds that can be used in medicine as antibacterial, antifungal, antiviral, antioxidant, and…”
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Full Regio- and Stereoselective Protocol for the Synthesis of New Nicotinoids via Cycloaddition Processes with the Participation of Trans-Substituted Nitroethenes: Comprehensive Experimental and MEDT Study
Published in Molecules (Basel, Switzerland) (17-04-2023)“…[3 + 2] Cycloaddition reactions with the participation of -C-(3-pyridyl)- -methylnitrone and series of -2-R-nitroethenes were both experimentally and…”
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5
On the Question of the Formation of Nitro-Functionalized 2,4-Pyrazole Analogs on the Basis of Nitrylimine Molecular Systems and 3,3,3-Trichloro-1-Nitroprop-1-Ene
Published in Molecules (Basel, Switzerland) (01-12-2022)“…Experimental and theoretical studies on the reaction between ( )-3,3,3-trichloro-1-nitroprop-1-ene and -(4-bromophenyl)-C-arylnitrylimine were performed. It…”
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Low-Molecular-Weight Organogelators Based on N -dodecanoyl-L-amino Acids-Energy Frameworks and Supramolecular Synthons
Published in Materials (11-01-2023)“…Lauric acid was used to synthesize the low-molecular-weight organogelators (LMOGs), derivatives of two endogenous (L)-alanine, (L)-leucine, and three exogenous…”
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Silver Is Not Equal to Silver: Synthesis and Evaluation of Silver Nanoparticles with Low Biological Activity, and Their Incorporation into C12Alanine-Based Hydrogel
Published in Molecules (Basel, Switzerland) (25-01-2023)“…A new type of silver nanoparticles (AgNPs) was prepared and comprehensively studied. Scanning electron microscopy (SEM) and dynamic light scattering (DLS)…”
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New Supramolecular Drug Carriers: The Study of Organogel Conjugated Gold Nanoparticles
Published in Molecules (Basel, Switzerland) (09-12-2021)“…An aqueous solution of sodium citrate stabilized gold nanoparticles (AuNP) in the presence of lauroyl-L-alanine (C ALA) forms a stable gel. The structure of…”
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A Modular Approach to Atropisomeric Bisphosphines of Diversified Electronic Density on Phosphorus Atoms
Published in Molecules (Basel, Switzerland) (27-08-2022)“…The series of C2-symmetric biaryl core-based non-racemic bisphosphines possessing substituents of different electronic properties: both EDG and EWG were…”
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A straightforward, environmentally beneficial synthesis of spiro[diindeno[1,2-b:2′,1′-e]pyridine-11,3′-indoline]-2′,10,12-triones mediated by a nano-ordered reusable catalyst
Published in Scientific reports (01-03-2021)“…A library of new spiro[diindeno[1,2-b:2′,1′- e ]pyridine-11,3′-indoline]-2′,10,12-trione derivatives has been prepared in an efficient, one-pot pseudo…”
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A Single Biaryl Monophosphine Ligand Motif—The Multiverse of Coordination Modes
Published in Inorganics (01-10-2023)“…Biaryl monophosphines are important precursors to active catalysts of palladium-mediated cross-coupling reactions. The efficiency of the phosphine-based…”
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An Efficient Asymmetric Cross-Coupling Reaction in Aqueous Media Mediated by Chiral Chelating Mono Phosphane Atropisomeric Biaryl Ligand
Published in Catalysts (01-02-2023)“…The enantiomerically pure ligand BisNap-Phos was obtained in a straightforward sequence of reactions beginning with inexpensive starting materials under the…”
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13
New Rigid Polycyclic Bis(phosphane) for Asymmetric Catalysis
Published in Molecules (Basel, Switzerland) (05-02-2019)“…A simple, highly efficient synthesis of a series of novel chiral non-racemic rigid tetracyclic phosphorus ligands, applicable in important chemical asymmetric…”
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Antifungal Agent 4-AN Changes the Genome-Wide Expression Profile, Downregulates Virulence-Associated Genes and Induces Necrosis in Candida albicans Cells
Published in Molecules (Basel, Switzerland) (25-06-2020)“…In the light of the increasing occurrence of antifungal resistance, there is an urgent need to search for new therapeutic strategies to overcome this…”
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The Anti- Candida albicans Agent 4-AN Inhibits Multiple Protein Kinases
Published in Molecules (Basel, Switzerland) (02-01-2019)“…Small molecules containing quinone and/or oxime moieties have been found as promising anti-fungal agents. One of them is 4-AN, a recently reported potent anti-…”
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A Quantum-Chemical DFT Approach to Elucidation of the Chirality Transfer Mechanism of the Enantioselective Suzuki–Miyaura Cross-Coupling Reaction
Published in Journal of chemistry (01-01-2017)“…The DFT calculations of the simplified model of the asymmetric Suzuki–Miyaura coupling reaction were performed at the M062x/LANL2DZ theory level at first. It…”
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Novel functionalized β-nitrostyrenes: Promising candidates for new antibacterial drugs
Published in Saudi pharmaceutical journal (01-05-2019)“…[Display omitted] •A homogenous series of β-EWG functionalyzed β-nitrostyrenes was synthesized and characterized by IR, UV, 1H NMR and 13C NMR spectra.•The…”
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The utilization of chiral phosphorus ligands in atroposelective cross-coupling reactions
Published in Phosphorus, sulfur, and silicon and the related elements (01-02-2016)“…Atroposelective synthesis of axially chiral biaryls mediated by palladium complexes of chiral phosphorus ligands is discussed. Analysis of the literature data…”
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A General Phenomenon of Spontaneous Amplification of Optical Purity under Achiral Chromatographic Conditions
Published in Symmetry (Basel) (01-05-2019)“…This work explores the behavior of chiral compound mixtures enriched in one of the enantiomers whilst a typical chromatography on the achiral stationary phase…”
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Green in water sonochemical synthesis of tetrazolopyrimidine derivatives by a novel core-shell magnetic nanostructure catalyst
Published in Ultrasonics sonochemistry (01-05-2018)“…[Display omitted] •A new hybrid organic-inorganic core-shell nanomagnetic catalyst is designed and developed.•It was characterized by FT-IR, SEM, EDX, TEM, TGA…”
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