Search Results - "Demchuk, Andrew"

Endovascular thrombectomy after large-vessel ischaemic stroke: a meta-analysis of individual patient data from five randomised trials by Goyal, Mayank, Prof, Menon, Bijoy K, MD, van Zwam, Wim H, MD, Dippel, Diederik W J, Prof, Mitchell, Peter J, Prof, Demchuk, Andrew M, Prof, Dávalos, Antoni, Prof, Majoie, Charles B L M, Prof, van der Lugt, Aad, Prof, de Miquel, Maria A, MD, Donnan, Geoffrey A, Prof, Roos, Yvo B W E M, Prof, Bonafe, Alain, Prof, Jahan, Reza, MD, Diener, Hans-Christoph, Prof, van den Berg, Lucie A, MD, Levy, Elad I, Prof, Berkhemer, Olvert A, MD, Pereira, Vitor M, MD, Rempel, Jeremy, MD, Millán, Mònica, MD, Davis, Stephen M, Prof, Roy, Daniel, Prof, Thornton, John, MD, Román, Luis San, MD, Ribó, Marc, MD, Beumer, Debbie, MD, Stouch, Bruce, Prof, Brown, Scott, PhD, Campbell, Bruce C V, MD, van Oostenbrugge, Robert J, Prof, Saver, Jeffrey L, Prof, Hill, Michael D, Prof, Jovin, Tudor G, Dr

“…Summary Background In 2015, five randomised trials showed efficacy of endovascular thrombectomy over standard medical care in patients with acute ischaemic…”
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Multiphase CT Angiography: A New Tool for the Imaging Triage of Patients with Acute Ischemic Stroke by Menon, Bijoy K, d'Esterre, Christopher D, Qazi, Emmad M, Almekhlafi, Mohammed, Hahn, Leszek, Demchuk, Andrew M, Goyal, Mayank

“…To describe the use of an imaging selection tool, multiphase computed tomographic (CT) angiography, in patients with acute ischemic stroke (AIS) and to…”
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Machine Learning for Detecting Early Infarction in Acute Stroke with Non-Contrast-enhanced CT by Qiu, Wu, Kuang, Hulin, Teleg, Ericka, Ospel, Johanna M, Sohn, Sung Il, Almekhlafi, Mohammed, Goyal, Mayank, Hill, Michael D, Demchuk, Andrew M, Menon, Bijoy K

“…Background Identifying the presence and extent of infarcted brain tissue at baseline plays a crucial role in the treatment of patients with acute ischemic…”
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Time to angiographic reperfusion and clinical outcome after acute ischaemic stroke: an analysis of data from the Interventional Management of Stroke (IMS III) phase 3 trial by Khatri, Pooja, Prof, Yeatts, Sharon D, PhD, Mazighi, Mikael, MD, Broderick, Joseph P, Prof, Liebeskind, David S, Prof, Demchuk, Andrew M, Prof, Amarenco, Pierre, Prof, Carrozzella, Janice, MSN, Spilker, Judith, BSN, Foster, Lydia D, PhD, Goyal, Mayank, Prof, Hill, Michael D, Prof, Palesch, Yuko Y, Prof, Jauch, Edward C, Prof, Haley, E Clarke, Prof, Vagal, Achala, MD, Tomsick, Thomas A, Prof

“…Summary Background The IMS III trial did not show a clinical benefit of endovascular treatment compared with intravenous alteplase (recombinant tissue…”
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eTICI reperfusion: defining success in endovascular stroke therapy by Liebeskind, David S, Bracard, Serge, Guillemin, Francis, Jahan, Reza, Jovin, Tudor G, Majoie, Charles Blm, Mitchell, Peter J, van der Lugt, Aad, Menon, Bijoy K, San Román, Luis, Campbell, Bruce Cv, Muir, Keith W, Hill, Michael D, Dippel, Diederik Wj, Saver, Jeffrey L, Demchuk, Andrew M, Dávalos, Antoni, White, Philip, Brown, Scott, Goyal, Mayank

“…Revascularization after endovascular therapy for acute ischemic stroke is measured by the Thrombolysis In Cerebral Infarction (TICI) scale, yet variability…”
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Thrombectomy within 8 Hours after Symptom Onset in Ischemic Stroke by Jovin, Tudor G, Chamorro, Angel, Cobo, Erik, de Miquel, María A, Molina, Carlos A, Rovira, Alex, San Román, Luis, Serena, Joaquín, Abilleira, Sonia, Ribó, Marc, Millán, Mònica, Urra, Xabier, Cardona, Pere, López-Cancio, Elena, Tomasello, Alejandro, Castaño, Carlos, Blasco, Jordi, Aja, Lucía, Dorado, Laura, Quesada, Helena, Rubiera, Marta, Hernandez-Pérez, María, Goyal, Mayank, Demchuk, Andrew M, von Kummer, Rüdiger, Gallofré, Miquel, Dávalos, Antoni

“…In this randomized trial involving patients with acute ischemic stroke with proximal anterior circulation occlusion, endovascular treatment with a Solitaire…”
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Thrombolytic therapies for ischemic stroke: Triumphs and future challenges by Moussaddy, Aimen, Demchuk, Andrew M., Hill, Michael D.

“…Acute stroke therapy has significantly evolved over the last two decades. The two main advances have been the approval of intravenous chemical thrombolysis in…”
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Thrombectomy for anterior circulation stroke beyond 6 h from time last known well (AURORA): a systematic review and individual patient data meta-analysis by Jovin, Tudor G, Nogueira, Raul G, Lansberg, Maarten G, Demchuk, Andrew M, Martins, Sheila O, Mocco, J, Ribo, Marc, Jadhav, Ashutosh P, Ortega-Gutierrez, Santiago, Hill, Michael D, Lima, Fabricio O, Haussen, Diogo C, Brown, Scott, Goyal, Mayank, Siddiqui, Adnan H, Heit, Jeremy J, Menon, Bijoy K, Kemp, Stephanie, Budzik, Ron, Urra, Xabier, Marks, Michael P, Costalat, Vincent, Liebeskind, David S, Albers, Gregory W

“…Trials examining the benefit of thrombectomy in anterior circulation proximal large vessel occlusion stroke have enrolled patients considered to have…”
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Modeling Stroke Patient Transport for All Patients With Suspected Large-Vessel Occlusion by Holodinsky, Jessalyn K, Williamson, Tyler S, Demchuk, Andrew M, Zhao, Henry, Zhu, Luke, Francis, Michael J, Goyal, Mayank, Hill, Michael D, Kamal, Noreen

“…Ischemic stroke with large-vessel occlusion can be treated with alteplase and/or endovascular therapy; however, the administration of each treatment is time…”
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Low Rates of Acute Recanalization With Intravenous Recombinant Tissue Plasminogen Activator in Ischemic Stroke: Real-World Experience and a Call for Action by BHATIA, Rohit, HILL, Michael D, SHOBHA, Nandavar, MENON, Bijoy, BAL, Simerpreet, KOCHAR, Puneet, WATSON, Tim, GOYAL, Mayank, DEMCHUK, Andrew M

“…Acute rates of recanalization after intravenous (IV) recombinant tissue plasminogen activator (rt-PA) in proximal vessel occlusion have been estimated…”
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Economic Evaluation of Andexanet Versus Prothrombin Complex Concentrate for Reversal of Factor Xa-Associated Intracranial Hemorrhage by Micieli, Andrew, Demchuk, Andrew M., Wijeysundera, Harindra C.

“…[Figure: see text]…”
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Scientific Rationale for the Inclusion and Exclusion Criteria for Intravenous Alteplase in Acute Ischemic Stroke: A Statement for Healthcare Professionals From the American Heart Association/American Stroke Association by Demaerschalk, Bart M, Kleindorfer, Dawn O, Adeoye, Opeolu M, Demchuk, Andrew M, Fugate, Jennifer E, Grotta, James C, Khalessi, Alexander A, Levy, Elad I, Palesch, Yuko Y, Prabhakaran, Shyam, Saposnik, Gustavo, Saver, Jeffrey L, Smith, Eric E

“…PURPOSE—To critically review and evaluate the science behind individual eligibility criteria (indication/inclusion and contraindications/exclusion criteria)…”
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Prediction of haematoma growth and outcome in patients with intracerebral haemorrhage using the CT-angiography spot sign (PREDICT): a prospective observational study by Demchuk, Andrew M, Dr, Prof, Dowlatshahi, Dar, MD, Rodriguez-Luna, David, MD, Molina, Carlos A, Prof, Blas, Yolanda Silva, MD, Dzialowski, Imanuel, MD, Kobayashi, Adam, MD, Boulanger, Jean-Martin, MD, Lum, Cheemun, MD, Gubitz, Gord, MD, Padma, Vasantha, Prof, Roy, Jayanta, MD, Kase, Carlos S, Prof, Kosior, Jayme, PhD, Bhatia, Rohit, MD, Tymchuk, Sarah, BSc, Subramaniam, Suresh, MD, Gladstone, David J, MD, Hill, Michael D, Prof, Aviv, Richard I, MBChB

“…Summary Background In patients with intracerebral haemorrhage (ICH), early haemorrhage expansion affects clinical outcome. Haemostatic treatment reduces…”
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Thrombectomy for Stroke at 6 to 16 Hours with Selection by Perfusion Imaging by Albers, Gregory W, Marks, Michael P, Kemp, Stephanie, Christensen, Soren, Tsai, Jenny P, Ortega-Gutierrez, Santiago, McTaggart, Ryan A, Torbey, Michel T, Kim-Tenser, May, Leslie-Mazwi, Thabele, Sarraj, Amrou, Kasner, Scott E, Ansari, Sameer A, Yeatts, Sharon D, Hamilton, Scott, Mlynash, Michael, Heit, Jeremy J, Zaharchuk, Greg, Kim, Sun, Carrozzella, Janice, Palesch, Yuko Y, Demchuk, Andrew M, Bammer, Roland, Lavori, Philip W, Broderick, Joseph P, Lansberg, Maarten G

“…In this trial in patients with stroke who had a mismatch between sizes of early infarction and a hypoperfused brain region, endovascular thrombectomy at 6 to…”
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Factor XIa inhibition with asundexian after acute non-cardioembolic ischaemic stroke (PACIFIC-Stroke): an international, randomised, double-blind, placebo-controlled, phase 2b trial by Shoamanesh, Ashkan, Mundl, Hardi, Smith, Eric E, Masjuan, Jaime, Milanov, Ivan, Hirano, Teruyuki, Agafina, Alina, Campbell, Bruce, Caso, Valeria, Mas, Jean-Louis, Dong, Qiang, Turcani, Peter, Christensen, Hanne, Ferro, Jose M, Veltkamp, Roland, Mikulik, Robert, De Marchis, Gian Marco, Robinson, Thompson, Lemmens, Robin, Stepien, Adam, Greisenegger, Stefan, Roine, Risto, Csiba, Laszlo, Khatri, Pooja, Coutinho, Jonathan, Lindgren, Arne G, Demchuk, Andrew M, Colorado, Pablo, Kirsch, Bodo, Neumann, Christoph, Heenan, Laura, Xu, Lizhen, Connolly, Stuart J, Hart, Robert G

“…Asundexian (Bayer AG, Leverkusen, Germany), an oral small molecule factor XIa (FXIa) inhibitor, might prevent thrombosis without increasing bleeding…”
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Analysis of Workflow and Time to Treatment on Thrombectomy Outcome in the Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) Randomized, Controlled Trial by Menon, Bijoy K, Sajobi, Tolulope T, Zhang, Yukun, Rempel, Jeremy L, Shuaib, Ashfaq, Thornton, John, Williams, David, Roy, Daniel, Poppe, Alexandre Y, Jovin, Tudor G, Sapkota, Biggya, Baxter, Blaise W, Krings, Timo, Silver, Frank L, Frei, Donald F, Fanale, Christopher, Tampieri, Donatella, Teitelbaum, Jeanne, Lum, Cheemun, Dowlatshahi, Dar, Eesa, Muneer, Lowerison, Mark W, Kamal, Noreen R, Demchuk, Andrew M, Hill, Michael D, Goyal, Mayank

“…BACKGROUND—The Endovascular Treatment for Small Core and Proximal Occlusion Ischemic Stroke (ESCAPE) trial used innovative imaging and aggressive target time…”
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Full Study Report of Andexanet Alfa for Bleeding Associated with Factor Xa Inhibitors by Connolly, Stuart J, Crowther, Mark, Eikelboom, John W, Gibson, C. Michael, Curnutte, John T, Lawrence, John H, Yue, Patrick, Bronson, Michele D, Lu, Genmin, Conley, Pamela B, Verhamme, Peter, Schmidt, Jeannot, Middeldorp, Saskia, Cohen, Alexander T, Beyer-Westendorf, Jan, Albaladejo, Pierre, Lopez-Sendon, Jose, Demchuk, Andrew M, Pallin, Daniel J, Concha, Mauricio, Goodman, Shelly, Leeds, Janet, Souza, Sonia, Siegal, Deborah M, Zotova, Elena, Meeks, Brandi, Ahmad, Sadia, Nakamya, Juliet, Milling, Truman J

“…In a single-group trial, 352 patients with acute major bleeding while taking a factor Xa inhibitor were treated with andexanet. Andexanet markedly reduced…”
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The emerging value of serum D-dimer measurement in the work-up and management of ischemic stroke by Ohara, Tomoyuki, Farhoudi, Mehdi, Bang, Oh Young, Koga, Masatoshi, Demchuk, Andrew M

“…Background Elevated D-dimer levels are a marker of both thrombin formation and fibrinolysis. Currently D-dimer measurement is routinely used for ruling out…”
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Association of Clinical, Imaging, and Thrombus Characteristics With Recanalization of Visible Intracranial Occlusion in Patients With Acute Ischemic Stroke by Menon, Bijoy K, Al-Ajlan, Fahad S, Najm, Mohamed, Puig, Josep, Castellanos, Mar, Dowlatshahi, Dar, Calleja, Ana, Sohn, Sung-Il, Ahn, Seong H, Poppe, Alex, Mikulik, Robert, Asdaghi, Negar, Field, Thalia S, Jin, Albert, Asil, Talip, Boulanger, Jean-Martin, Smith, Eric E, Coutts, Shelagh B, Barber, Phil A, Bal, Simerpreet, Subramanian, Suresh, Mishra, Sachin, Trivedi, Anurag, Dey, Sadanand, Eesa, Muneer, Sajobi, Tolulope, Goyal, Mayank, Hill, Michael D, Demchuk, Andrew M

“…IMPORTANCE: Recanalization of intracranial thrombus is associated with improved clinical outcome in patients with acute ischemic stroke. The association of…”
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Time to Treatment With Endovascular Thrombectomy and Outcomes From Ischemic Stroke: A Meta-analysis by Saver, Jeffrey L, Goyal, Mayank, van der Lugt, Aad, Menon, Bijoy K, Majoie, Charles B. L. M, Dippel, Diederik W, Campbell, Bruce C, Nogueira, Raul G, Demchuk, Andrew M, Tomasello, Alejandro, Cardona, Pere, Devlin, Thomas G, Frei, Donald F, du Mesnil de Rochemont, Richard, Berkhemer, Olvert A, Jovin, Tudor G, Siddiqui, Adnan H, van Zwam, Wim H, Davis, Stephen M, Castaño, Carlos, Sapkota, Biggya L, Fransen, Puck S, Molina, Carlos, van Oostenbrugge, Robert J, Chamorro, Ángel, Lingsma, Hester, Silver, Frank L, Donnan, Geoffrey A, Shuaib, Ashfaq, Brown, Scott, Stouch, Bruce, Mitchell, Peter J, Davalos, Antoni, Roos, Yvo B. W. E. M, Hill, Michael D

“…IMPORTANCE: Endovascular thrombectomy with second-generation devices is beneficial for patients with ischemic stroke due to intracranial large-vessel…”
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