Search Results - "Demchuk, A M"

Defining hematoma expansion in intracerebral hemorrhage: Relationship with patient outcomes by DOWLATSHAHI, D, DEMCHUK, A. M, FLAHERTY, M. L, ALI, M, LYDEN, P. L, SMITH, E. E

“…Hematoma expansion (HE) is a surrogate marker in intracerebral hemorrhage (ICH) trials. However, the amount of HE necessary to produce poor outcomes in an…”
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Regional Leptomeningeal Score on CT Angiography Predicts Clinical and Imaging Outcomes in Patients with Acute Anterior Circulation Occlusions by MENON, B. K, SMITH, E. E, MODI, J, PATEL, S. K, BHATIA, R, WATSON, T. W. J, HILL, M. D, DEMCHUK, A. M, GOYAL, M

“…The regional leptomeningeal score is a strong and reliable imaging predictor of good clinical outcomes in acute anterior circulation ischemic strokes and can…”
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CT Angiography Clot Burden Score and Collateral Score: Correlation with Clinical and Radiologic Outcomes in Acute Middle Cerebral Artery Infarct by Tan, I.Y.L, Demchuk, A.M, Hopyan, J, Zhang, L, Gladstone, D, Wong, K, Martin, M, Symons, S.P, Fox, A.J, Aviv, R.I

“…Clot extent, location, and collateral integrity are important determinants of outcome in acute stroke. We hypothesized that a novel clot burden score (CBS) and…”
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Imaging of the brain in acute ischaemic stroke: comparison of computed tomography and magnetic resonance diffusion-weighted imaging by Barber, P A, Hill, M D, Eliasziw, M, Demchuk, A M, Pexman, J H W, Hudon, M E, Tomanek, A, Frayne, R, Buchan, A M

“…Background and objectives: Controversy exists about the optimal imaging technique in acute stroke. It was hypothesised that CT is comparable with DWI, when…”
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Why are stroke patients excluded from TPA therapy? An analysis of patient eligibility by BARBER, P. A, ZHANG, J, DEMCHUK, A. M, HILL, M. D, BUCHAN, A. M

“…Thrombolytic therapy for acute stroke (<3 hours) will not have a major impact on death and dependency unless it is accessible to more patients. To determine…”
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Early stroke risk and ABCD2 score performance in tissue- vs time-defined TIA: A multicenter study by GILES, M. F, ALBERS, G. W, JOHNSTON, S. C, KELLY, P. J, KIM, A. S, LABREUCHE, J, LAVALLEE, P. C, MAS, J.-L, MERWICK, A, OLIVOT, J. M, PURROY, F, ROSAMOND, W. D, AMARENCO, P, SCIOLLA, R, ROTHWELL, P. M, ARSAVA, E. M, ASIMOS, A. W, AY, H, CALVET, D, COUTTS, S. B, CUCCHIARA, B. L, DEMCHUK, A. M

“…Stroke risk immediately after TIA defined by time-based criteria is high, and prognostic scores (ABCD2 and ABCD3-I) have been developed to assist management…”
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Identification of penumbra and infarct in acute ischemic stroke using computed tomography perfusion-derived blood flow and blood volume measurements by MURPHY, B. D, FOX, A. J, SYMONS, S, GULKA, I. B, BELETSKY, V, PELZ, D, HACHINSKI, V, CHAN, R, LEE, T.-Y, LEE, D. H, SAHLAS, D. J, BLACK, S. E, HOGAN, M. J, COUTTS, S. B, DEMCHUK, A. M, GOYAL, M, AVIV, R. I

“…We investigated whether computed tomography (CT) perfusion-derived cerebral blood flow (CBF) and cerebral blood volume (CBV) could be used to differentiate…”
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Symptomatic intracerebral hemorrhage and recanalization after IV rt-PA A multicenter study by SAQQUR, M, TSIVGOULIS, G, MOLINA, C. A, DEMCHUK, A. M, SIDDIQUI, M, ALVAREZ-SABIN, J, UCHINO, K, CALLEJA, S, ALEXANDROV, A. V

“…Symptomatic intracerebral hemorrhage (sICH) is the most unfavorable complication after IV thrombolytic treatment. We aimed to determine the relationship…”
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Predictors of good outcome after intravenous tPA for acute ischemic stroke by DEMCHUK, A. M, TANNE, D, HILL, M. D, KASNER, S. E, HANSON, S, GROND, M, LEVINE, S. R

“…Thrombolytic therapy for acute ischemic stroke with IV alteplase is increasingly well established in North America but not elsewhere. Baseline factors that…”
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Rebleeding leads to poor outcome in ultra-early craniotomy for intracerebral hemorrhage by MORGENSTERN, L. B, DEMCHUK, A. M, KIM, D. H, FRANKOWSKI, R. F, GROTTA, J. C

“…A modest benefit was previously demonstrated for hematoma evacuation within 12 hours of intracerebral hemorrhage onset. Perhaps surgery within 4 hours would…”
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Silent ischemia in minor stroke and TIA patients identified on MR imaging by COUTTS, S. B, HILL, M. D, SIMON, J. E, SOHN, C.-H, SCOTT, J. N, DEMCHUK, A. M

“…In a general population of patients with stroke, the rate of new MRI lesions at 1 week was much higher than expected. With patients with minor stroke and TIA…”
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Acute ischemic lesions of varying ages predict risk of ischemic events in stroke/TIA patients by SYLAJA, P. N, COUTTS, S. B, SUBRAMANIAM, S, HILL, M. D, ELIASZIW, M, DEMCHUK, A. M

“…Multiple ischemic lesions identified by diffusion-weighted imaging (DWI) have been shown to predict high risk of future ischemic events. However, the…”
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Using the Baseline CT Scan to Select Acute Stroke Patients for IV-IA Therapy by Hill, M.D, Demchuk, A.M, Tomsick, T.A, Palesch, Y.Y, Broderick, J.P, on behalf of IMS-1 Investigators

“…Intra-arterial therapies for acute ischemic stroke are increasingly available. Intravenous therapy (IV) followed immediately by intra-arterial therapy (IA) has…”
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Use of the Alberta Stroke Program Early CT Score (ASPECTS) for Assessing CT Scans in Patients with Acute Stroke by Pexman, J. H. Warwick, Barber, Philip A, Hill, Michael D, Sevick, Robert J, Demchuk, Andrew M, Hudon, Mark E, Hu, William Y, Buchan, Alastair M

“…Clinicians are insecure reading CT scans by using the one-third rule for acute middle cerebral artery stroke (1/3 MCA rule) before treating patients with…”
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CT Angiography Source Images Predict Final Infarct Extent in Patients with Basilar Artery Occlusion by Puetz, V, Sylaja, P.N, Hill, M.D, Coutts, S.B, Dzialowski, I, Becker, U, Gahn, G, von Kummer, R, Demchuk, A.M

“…The posterior circulation Acute Stroke Prognosis Early CT Score (pc-ASPECTS) is a 10-point grading system to quantify ischemic changes in the posterior…”
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Role of CT Angiographic Plaque Morphologic Characteristics in Addition to Stenosis in Predicting the Symptomatic Side in Carotid Artery Disease by EESA, M, HILL, M. D, AL-KHATHAAMI, A, AL-ZAWAHMAH, M, SHARMA, P, MENON, B. K, TYMCHUK, S, DEMCHUK, A. M, GOYAL, M

“…Atherosclerotic disease of the carotid artery is an important cause of ischemic stroke. We evaluated carotid plaque morphologic features by using CTA in…”
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Role of Recanalization in Acute Stroke Outcome: Rationale for a CT Angiogram-Based "Benefit of Recanalization" Model by Rosenthal, E.S, Schwamm, L.H, Roccatagliata, L, Coutts, S.B, Demchuk, A.M, Schaefer, P.W, Gonzalez, R.G, Hill, M.D, Halpern, E.F, Lev, M.H

“…In acute middle cerebral artery (MCA) stroke, CT angiographic (CTA) source images (CTA-SI) identify tissue likely to infarct despite early recanalization. This…”
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Automated ASPECTS on Noncontrast CT Scans in Patients with Acute Ischemic Stroke Using Machine Learning by Kuang, H, Najm, M, Chakraborty, D, Maraj, N, Sohn, S I, Goyal, M, Hill, M D, Demchuk, A M, Menon, B K, Qiu, W

“…Alberta Stroke Program Early CT Score (ASPECTS) was devised as a systematic method to assess the extent of early ischemic change on noncontrast CT (NCCT) in…”
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Hemi-orolingual angioedema and ACE inhibition after alteplase treatment of stroke by Hill, M D, Lye, T, Moss, H, Barber, P A, Demchuk, A M, Newcommon, N J, Green, T L, Kenney, C, Cole-Haskayne, A, Buchan, A M

“…One hundred seventy-six consecutive patients treated with IV tissue plasminogen activator (tPA) for acute ischemic stroke were examined prospectively, and…”
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High rate of complete recanalization and dramatic clinical recovery during tPA infusion when continuously monitored with 2-MHz transcranial Doppler monitoring by ALEXANDROV, A. V, DEMCHUK, A. M, FELBERG, R. A, CHRISTOU, I, BARBER, P. A, BURGIN, W. S, MALKOFF, M, WOJNER, A. W, GROTTA, J. C

“…Clot dissolution with tissue plasminogen activator (tPA) can lead to early clinical recovery after stroke. Transcranial Doppler (TCD) with low MHz frequency…”
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