Search Results - "Demchenkova, E. Yu"
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Comparative evaluation of recommendations for preclinical studies of transporter-mediated drug–drug interactions
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (01-12-2023)“…Scientific relevance. Sound recommendations for preclinical studies of transporter- mediated pharmacokinetic interactions of medicinal products can help…”
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2
Clinical Pharmacology of Antimicrobials: Focus on the Safety of Vancomycin and Linezolid
Published in Bezopasnostʹ i risk farmakoterapii (Online) (01-12-2023)“…Scientific relevance. Vancomycin and linezolid are the antibacterial agents of choice for severe infections caused by multidrug-resistant pathogens, including…”
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3
Features of toxic nephropathy development during antibiotic therapy
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (01-12-2023)“…Scientist relevance. Antibacterials can have nephrotoxic effects because medicinal products of this class are primarily excreted by the kidneys. Aim. The study…”
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Aspects of the Safe Use of Antibacterial Drugs in Community-Acquired Pneumonia: the Implications of Drug-Drug Interactions
Published in Antibiotiki i himioterapiâ (05-08-2022)“…Background. Drug-drug interactions can seriously affect the safety profile of a drug and are an important problem worldwide. Due to the aging of the…”
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Retrospective Analysis of the Safety of Antibacterial Medicinal Products for Elderly Patients with Community-Acquired Lower Respiratory Tract Infections
Published in Bezopasnostʹ i risk farmakoterapii (Online) (01-03-2023)“…Cephalosporins are the empirical antibiotic therapy (ABT) of choice for patients with community-acquired pneumonia (CAP). When treated with antibiotics,…”
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Experimental Cell Line Models for Nephrotoxicity Screening
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (02-10-2021)“…The aim of the study was to review literature data on cell models for experimental assessment of drug nephrotoxicity in vitro . Because of nephrotoxicity, 2%…”
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Evaluation of the Efficacy and Safety of Initial Empirical Antibiotic Therapy for Community-Acquired Pneumonia in Middle-Aged People
Published in Bezopasnostʹ i risk farmakoterapii (Online) (03-07-2022)“…β-lactam antibiotics, including cephalosporins, are the drugs of choice for empirical antibiotic therapy (ABT) in patients with community-acquired pneumonia…”
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Experience of Using Therapeutic Drug Monitoring to Control the Safety of Vancomycin in Intensive Care Unit Patients with Sepsis
Published in Bezopasnostʹ i risk farmakoterapii (Online) (03-07-2022)“…Vancomycin is prescribed to patients in serious condition with infections caused by Gram-positive microorganisms; however, if the therapeutic plasma…”
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9
Pantoprazole niche among the GERD-medicines
Published in Medicinskij sovet (22-10-2020)“…Main groups of antisecretory drugs used in the treatment of acid-dependent diseases, including gastroesophageal reflux disease (GERD), are described in a…”
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β-Lactam Antibiotics—Drug-Drug Interaction Mediated by Organic Anion Transporters OAT1 and OAT3
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (18-09-2020)“…Organic anion transporters OAT1 and OAT3 play a key role in elimination of most β-lactam antibiotics. Since nonsteroidal anti-inflammatory drugs, antivirals,…”
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11
Inhibitors in the Management of Patients with Atherosclerotic Cardiovascular Diseases: Guidelines and Reimbursement Issues
Published in Rat͡s︡ionalʹnai͡a︡ farmakoterapii͡a︡ v kardiologii (02-09-2020)“…Current guidelines for the management of patients with dyslipidemia define low-density lipoprotein cholesterol (LDL-C) as the primary target in addressing…”
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Major Aspects of Detection and Monitoring of Adverse Reactions Associated with Cephalosporin Antibiotic Treatment
Published in Bezopasnostʹ i risk farmakoterapii (Online) (16-03-2021)“…Widespread use of cephalosporin antibiotics in clinical practice calls for greater attention to the risk of adverse drug reactions. Information on serious or…”
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Topical Issues of Drug Safety, Possibilities of Improving of Pharmacovigilance
Published in Bezopasnostʹ i risk farmakoterapii (Online) (17-09-2019)“…Since 2010, Russia has been developing new drug legislation, internal quality control and safety of medical organizations, and has developed algorithms for…”
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14
PHARMACOGENETICS OF ORGANIC CATION TRANSPORTERS
Published in Bezopasnostʹ i risk farmakoterapii (Online) (21-06-2018)“…This article describes basic information about the classification, structure, substrate specificity and expression of organic cation transporters. The…”
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Pharmacogenetic Approaches to Enhancing Efficacy and Safety of Statins as Illustrated by the Example of Atorvastatin
Published in Bezopasnostʹ i risk farmakoterapii (Online) (26-03-2020)“…Statins are efficacious lipid-lowering drugs used for prevention of cardiovascular complications in patients with high blood cholesterol. The efficacy and…”
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16
The Mechanism of Action of Follistatin-like Protein-1 (FSTL-1)
Published in Vedomosti Naučnogo centra èkspertizy sredstv medicinskogo primeneniâ (Online) (03-12-2019)“…The paper provides current data on some proteins of the TGF- p family which are potentially capable of exerting a protective effect in diseases of the heart,…”
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Compendium of pH-sensitive polymers in gastroenterology drugs: focus on enteric coatings
Published in Medicinskij sovet (10-05-2024)“…This compendium for gastroenterologists and hepatologists contains information about pH-sensitive polymers used in dosage forms for oral administration and…”
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Generic drugs of direct antiviral action for the treatment of hepatitis C: features of bioequivalence studies
Published in Medicinskij sovet (25-05-2023)“…Introduction . In the last decade, approaches to the treatment of chronic viral hepatitis C (HCV) have undergone significant changes. The new WHO strategy aims…”
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Kinetics of Omeprazole Release from Enteric Dosage Forms of Different Manufacturers
Published in Pharmaceutical chemistry journal (2024)“…A comparative dissolution kinetics test (CDKT) related to proton-pump inhibitors (PPIs), particularly omeprazole, using dissolution media with pH 1.2 and 6.8…”
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20
Irritable bowel syndrome: modern ideas about pathology and the possibility of its correction
Published in Medicinskij sovet (04-11-2023)“…Among the defecating disorders with constipation or diarrhea, there is a group of major intestinal disorders defined by the Rome IV Diagnostic …”
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