Search Results - "Dembélé, Doulaye"
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A method for computing the Perron root for primitive matrices
Published in Numerical linear algebra with applications (01-01-2021)“…Summary Following the Perron theorem, the spectral radius of a primitive matrix is a simple eigenvalue. It is shown that for a primitive matrix A, there is a…”
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2
Fuzzy C-means method for clustering microarray data
Published in Bioinformatics (22-05-2003)“…Motivation: Clustering analysis of data from DNA microarray hybridization studies is essential for identifying biologically relevant groups of genes…”
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3
Fold change rank ordering statistics: a new method for detecting differentially expressed genes
Published in BMC bioinformatics (15-01-2014)“…Different methods have been proposed for analyzing differentially expressed (DE) genes in microarray data. Methods based on statistical tests that incorporate…”
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4
Analysis of high-throughput biological data using their rank values
Published in Statistical methods in medical research (01-08-2019)“…High-throughput biological technologies are routinely used to generate gene expression profiling or cytogenetics data. To achieve high performance, methods…”
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5
Co-translational assembly of mammalian nuclear multisubunit complexes
Published in Nature communications (15-04-2019)“…Cells dedicate significant energy to build proteins often organized in multiprotein assemblies with tightly regulated stoichiometries. As genes encoding…”
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6
Fragile X Mental Retardation Protein (FMRP) controls diacylglycerol kinase activity in neurons
Published in Proceedings of the National Academy of Sciences - PNAS (28-06-2016)“…Fragile X syndrome (FXS) is caused by the absence of the Fragile X Mental Retardation Protein (FMRP) in neurons. In the mouse, the lack of FMRP is associated…”
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7
Microglia Express Mu Opioid Receptor: Insights From Transcriptomics and Fluorescent Reporter Mice
Published in Frontiers in psychiatry (04-01-2019)“…Microglia activation contributes to chronic pain and to the adverse effects of opiate use such as analgesic tolerance and opioid-induced hyperalgesia. Both mu…”
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Subclinical endometritis in dairy cattle is associated with distinct mRNA expression patterns in blood and endometrium
Published in PloS one (02-08-2019)“…Cattle with subclinical endometritis (SCE) are sub-fertile and diagnosing subclinical uterine disease remains a challenge. The hypothesis for this study was…”
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β-Catenin activation synergizes with Pten loss and Myc overexpression in Notch-independent T-ALL
Published in Blood (01-08-2013)“…Wnt signaling is important for T-cell differentiation at the early CD4−CD8− stage and is subsequently downregulated with maturation. To assess the importance…”
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Tripartite Motif 24 (Trim24/Tif1α) Tumor Suppressor Protein Is a Novel Negative Regulator of Interferon (IFN)/Signal Transducers and Activators of Transcription (STAT) Signaling Pathway Acting through Retinoic Acid Receptor α (Rarα) Inhibition
Published in The Journal of biological chemistry (23-09-2011)“…Recent genetic studies in mice have established that the nuclear receptor coregulator Trim24/Tif1α suppresses hepatocarcinogenesis by inhibiting retinoic acid…”
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Comments on: fold change rank ordering statistics: a new method for detecting differentially expressed genes
Published in BMC bioinformatics (15-11-2016)“…We published a new method (BMC Bioinformatics 2014, 15:14) for searching for differentially expressed genes from two biological conditions datasets. The…”
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12
Responses to climatic and pathogen threats differ in biodynamic and conventional vines
Published in Scientific reports (15-11-2018)“…Viticulture is of high socio-economic importance; however, its prevalent practices severely impact the environment and human health, and criticisms from…”
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Novel insights into the relationships between dendritic cell subsets in human and mouse revealed by genome-wide expression profiling
Published in Genome Biology (24-01-2008)“…Dendritic cells (DCs) are a complex group of cells that play a critical role in vertebrate immunity. Lymph-node resident DCs (LN-DCs) are subdivided into…”
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Genome-wide Analysis of RARβ Transcriptional Targets in Mouse Striatum Links Retinoic Acid Signaling with Huntington’s Disease and Other Neurodegenerative Disorders
Published in Molecular neurobiology (01-07-2017)“…Retinoic acid (RA) signaling through retinoic acid receptors (RARs), known for its multiple developmental functions, emerged more recently as an important…”
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Circulating Human Eosinophils Share a Similar Transcriptional Profile in Asthma and Other Hypereosinophilic Disorders
Published in PloS one (02-11-2015)“…Eosinophils are leukocytes that are released into the peripheral blood in a phenotypically mature state and are capable of being recruited into tissues in…”
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Attitudes towards Genetic Information Delivered by High-Throughput Sequencing among Molecular Geneticists, Genetic Counselors, Medical Advisors and Students in France
Published in European journal of medical genetics (01-04-2020)“…High-throughput sequencing technologies performed in the clinical setting have the potential to reveal diverse genetic information. Whether it is initially…”
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Transcriptomic analysis of murine embryos lacking endogenous retinoic acid signaling
Published in PloS one (24-04-2013)“…Retinoic acid (RA), an active derivative of the liposoluble vitamin A (retinol), acts as an important signaling molecule during embryonic development,…”
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Short- and long-term gene expression profiles induced by inhaled TiO2 nanostructured aerosol in rat lung
Published in Toxicology and applied pharmacology (01-10-2018)“…The number of workers potentially exposed to nanoparticles (NPs) during industrial processes is increasing, although the toxicological properties of these…”
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The tumor suppressor Ikaros shapes the repertoire of notch target genes in T cells
Published in Science signaling (18-03-2014)“…The Notch signaling pathway is activated in many cell types, but its effects are cell type- and stage-specific. In the immune system, Notch activity is…”
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Systematic Gene Expression Mapping Clusters Nuclear Receptors According to Their Function in the Brain
Published in Cell (19-10-2007)“…Nuclear receptors (NRs) compose a large family of transcription factors that operate at the interface between genes and environment, acting as sensors and…”
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