Search Results - "Demaestri, Camila"
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Altered corticolimbic connectivity reveals sex-specific adolescent outcomes in a rat model of early life adversity
Published in eLife (20-01-2020)“…Exposure to early-life adversity (ELA) increases the risk for psychopathologies associated with amygdala-prefrontal cortex (PFC) circuits. While sex…”
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Central amygdala CRF+ neurons promote heightened threat reactivity following early life adversity in mice
Published in Nature communications (29-06-2024)“…Failure to appropriately predict and titrate reactivity to threat is a core feature of fear and anxiety-related disorders and is common following early life…”
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Cross-Generational Transmission of Early Life Stress Effects on HPA Regulators and Bdnf Are Mediated by Sex, Lineage, and Upbringing
Published in Frontiers in behavioral neuroscience (09-05-2019)“…Early life stress (ELS) is a potent developmental disruptor and increases the risk for psychopathology. Various forms of ELS have been studied in both humans…”
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Resource scarcity but not maternal separation provokes unpredictable maternal care sequences in mice and both upregulate Crh-associated gene expression in the amygdala
Published in Neurobiology of stress (01-09-2022)“…Early life adversity (ELA) is a major risk factor for the development of pathology, including anxiety disorders. Neurodevelopmental and behavioral outcomes…”
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Type of early life adversity confers differential, sex-dependent effects on early maturational milestones in mice
Published in Hormones and behavior (01-08-2020)“…Early life adversity (ELA) increases risk for negative health outcomes, with sex disparities in prevalence and form of ELA experienced and risk for…”
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Influence of Early Life Adversity on Amygdala-Dependent Threat Reactivity: Exploring the Role of Sex and Experience Type on Postnatal Development and Long-term Outcomes
Published 01-01-2023“…Experiencing early life adversity (ELA) increases the risk of anxiety disorders, such as generalized anxiety disorder and post-traumatic stress disorder, with…”
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Dissertation -
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40. Early Life Adversity in Mice Accelerates Age-Related Decline in Behavioral Pattern Separation
Published in Biological psychiatry (1969) (15-05-2024)Get full text
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8
22 kHz and 55 kHz ultrasonic vocalizations differentially influence neural and behavioral outcomes: Implications for modeling anxiety via auditory stimuli in the rat
Published in Behavioural brain research (15-03-2019)“…•Differential cFos activation to 22 kHz and 55 kHz ultrasonic vocalization playback.•Playback of aversive vocalizations increases anxiety-like behaviors.•22…”
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Effects of early life stress on cocaine conditioning and AMPA receptor composition are sex-specific and driven by TNF
Published in Brain, behavior, and immunity (01-05-2019)“…•Maternal separation increased PFC and NAc TNF levels in male, but not female rats.•Maternal separation decreased GluA2 in AMPA receptors in males, but not…”
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10
22kHz and 55kHz ultrasonic vocalizations differentially influence neural and behavioral outcomes: Implications for modeling anxiety via auditory stimuli in the rat
Published in Behavioural brain research (03-12-2018)“…The communicative role of ultrasonic vocalizations (USVs) in rats is well established, with distinct USVs indicative of different affective states. USVs in the…”
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Journal Article -
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Early life adversity reduces affiliative behavior with a stressed cagemate and leads to sex-specific alterations in corticosterone responses in adult mice
Published in Hormones and behavior (01-02-2024)“…Experiencing early life adversity (ELA) alters stress physiology and increases the risk for developing psychiatric disorders. The social environment can…”
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Journal Article