Search Results - "Delzenne, Nathalie M."
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The International Scientific Association for Probiotics and Prebiotics (ISAPP) consensus statement on the definition and scope of synbiotics
Published in Nature reviews. Gastroenterology & hepatology (01-11-2020)“…In May 2019, the International Scientific Association for Probiotics and Prebiotics (ISAPP) convened a panel of nutritionists, physiologists and…”
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Towards a more comprehensive concept for prebiotics
Published in Nature reviews. Gastroenterology & hepatology (01-05-2015)“…As understanding of the gut microbiota advances, the focus has shifted to ways to modulate the microbiota to improve health. One such strategy is the use of…”
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Cross-talk between Akkermansia muciniphila and intestinal epithelium controls diet-induced obesity
Published in Proceedings of the National Academy of Sciences - PNAS (28-05-2013)“…Obesity and type 2 diabetes are characterized by altered gut microbiota, inflammation, and gut barrier disruption. Microbial composition and the mechanisms of…”
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Modulation of the gut microbiota-adipose tissue-muscle interactions by prebiotics
Published in Journal of endocrinology (01-04-2021)“…The gut microbiota is now widely recognized as an important factor contributing to the regulation of host metabolic functions. Numerous studies describe an…”
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Gut microorganisms as promising targets for the management of type 2 diabetes
Published in Diabetologia (01-10-2015)“…Each human intestine harbours not only hundreds of trillions of bacteria but also bacteriophage particles, viruses, fungi and archaea, which constitute a…”
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Interaction between obesity and the gut microbiota: relevance in nutrition
Published in Annual review of nutrition (21-08-2011)“…This review examines mechanisms by which the bacteria present in the gut interact with nutrients and host biology to affect the risk of obesity and associated…”
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A purified membrane protein from Akkermansia muciniphila or the pasteurized bacterium improves metabolism in obese and diabetic mice
Published in Nature medicine (01-01-2017)“…Akkermansia muciniphila , a member of the gut microbiome, has been shown to improve metabolism in mice. Here it is reported that its pasteurization further…”
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Targeting gut microbiota in obesity: effects of prebiotics and probiotics
Published in Nature reviews. Endocrinology (01-11-2011)“…Gut microbes act as an environmental factor that affects an individual's physiology and metabolism, particularly in the context of obesity and its related…”
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GPR43/FFA2: physiopathological relevance and therapeutic prospects
Published in Trends in pharmacological sciences (Regular ed.) (01-04-2013)“…Research interest in free fatty acid-binding receptors has been growing during the past decade, with an aim to better understand the modulation of host…”
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Prebiotic effects of wheat arabinoxylan related to the increase in bifidobacteria, Roseburia and Bacteroides/Prevotella in diet-induced obese mice
Published in PloS one (09-06-2011)“…Alterations in the composition of gut microbiota--known as dysbiosis--has been proposed to contribute to the development of obesity, thereby supporting the…”
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Pasteurized Akkermansia muciniphila increases whole-body energy expenditure and fecal energy excretion in diet-induced obese mice
Published in Gut microbes (02-09-2020)“…Accumulating evidence points to Akkermansia muciniphila as a novel candidate to prevent or treat obesity-related metabolic disorders. We recently observed, in…”
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Intestinal permeability, gut-bacterial dysbiosis, and behavioral markers of alcohol-dependence severity
Published in Proceedings of the National Academy of Sciences - PNAS (21-10-2014)“…Alcohol dependence has traditionally been considered a brain disorder. Alteration in the composition of the gut microbiota has recently been shown to be…”
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Microbial Modulation of Energy Availability in the Colon Regulates Intestinal Transit
Published in Cell host & microbe (13-11-2013)“…Gut microbiota contribute to host metabolic efficiency by increasing energy availability through the fermentation of dietary fiber and production of…”
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Short-chain fatty acids are key mediators of the favorable effects of the Mediterranean diet on intestinal barrier integrity: data from the randomized controlled LIBRE trial
Published in The American journal of clinical nutrition (01-10-2022)“…The Mediterranean diet is associated with the prevention of diabetes, cardiovascular disease, and cancer, all of which are linked to intestinal barrier…”
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Endocannabinoids — at the crossroads between the gut microbiota and host metabolism
Published in Nature reviews. Endocrinology (01-03-2016)“…Key Points As gut microorganisms interact with host cells via several mechanisms, targeting the microbiota to treat metabolic disorders is an attractive…”
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Muscle wasting: The gut microbiota as a new therapeutic target?
Published in The international journal of biochemistry & cell biology (01-10-2013)“…Muscle wasting is characterized by a loss of muscle mass and strength, and occurs in several pathological conditions such as cancer, chronic heart failure,…”
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Microbiome of prebiotic-treated mice reveals novel targets involved in host response during obesity
Published in The ISME Journal (01-10-2014)“…The gut microbiota is involved in metabolic and immune disorders associated with obesity and type 2 diabetes. We previously demonstrated that prebiotic…”
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Targeting the gut microbiota with inulin-type fructans: preclinical demonstration of a novel approach in the management of endothelial dysfunction
Published in Gut (01-02-2018)“…To investigate the beneficial role of prebiotics on endothelial dysfunction, an early key marker of cardiovascular diseases, in an original mouse model linking…”
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Microbiome metabolomics reveals new drivers of human liver steatosis
Published in Nature medicine (01-07-2018)“…An integrative multiomics approach in nondiabetic obese women identifies phenylacetate as a microbial metabolite contributing to the accumulation of lipids in…”
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Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice
Published in Diabetes (New York, N.Y.) (01-06-2008)“…Changes in Gut Microbiota Control Metabolic Endotoxemia-Induced Inflammation in High-Fat Diet–Induced Obesity and Diabetes in Mice Patrice D. Cani 1 2 ,…”
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