Search Results - "Delwar, Zahid"

Oncolytic Virotherapy Blockade by Microglia and Macrophages Requires STAT1/3 by Delwar, Zahid M, Kuo, Yvonne, Wen, Yan H, Rennie, Paul S, Jia, William

“…The first oncolytic virotherapy employing HSV-1 (oHSV-1) was approved recently by the FDA to treat cancer, but further improvements in efficacy are needed to…”
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Tumour-specific triple-regulated oncolytic herpes virus to target glioma by Delwar, Zahid M, Liu, Guoyu, Kuo, Yvonne, Lee, Cleo, Bu, Luke, Rennie, Paul S, Jia, William W

“…Oncolytic herpes simplex virus type 1 (oHSV-1) therapy is an emerging treatment modality that selectively destroys cancer. Here we report use of a glioma…”
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Induction of Durable Antitumor Response by a Novel Oncolytic Herpesvirus Expressing Multiple Immunomodulatory Transgenes by Chouljenko, Dmitry V., Ding, Jun, Lee, I-Fang, Murad, Yanal M., Bu, Xuexian, Liu, Guoyu, Delwar, Zahid, Sun, Yi, Yu, Sheng, Samudio, Ismael, Zhao, Ronghua, Jia, William Wei-Guo

“…Oncolytic virotherapy is a promising new tool for cancer treatment, but direct lytic destruction of tumor cells is not sufficient and must be accompanied by…”
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Targeting carcinoembryonic antigen-expressing tumors using a novel transcriptional and translational dual-regulated oncolytic herpes simplex virus type 1 by Chouljenko, Dmitry V., Murad, Yanal M., Lee, I-Fang, Delwar, Zahid, Ding, Jun, Liu, Guoyu, Liu, Xiaohu, Bu, Xuexian, Sun, Yi, Samudio, Ismael, Jia, William Wei-Guo

“…VG2025 is a recombinant oncolytic herpes simplex virus type 1 (HSV-1) that uses transcriptional and translational dual regulation (TTDR) of critical viral…”
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Identification of a Hematopoietic Cell Dedifferentiation-Inducing Factor by Li, Yunyuan, Adomat, Hans, Guns, Emma Tomlinson, Hojabrpour, Payman, Duronio, Vincent, Curran, Terry-Ann, Jalili, Reza Baradar, Jia, William, Delwar, Zahid, Zhang, Yun, Elizei, Sanam Salimi, Ghahary, Aziz

“…It has long been realized that hematopoietic cells may have the capacity to trans‐differentiate into non‐lymphohematopoietic cells under specific conditions…”
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Prophylactic Vaccination and Intratumoral Boost with HER2-Expressing Oncolytic Herpes Simplex Virus Induces Robust and Persistent Immune Response against HER2-Positive Tumor Cells by Delwar, Zahid, Tatsiy, Olga, Chouljenko, Dmitry V, Lee, I-Fang, Liu, Guoyu, Liu, Xiaohu, Bu, Luke, Ding, Jun, Singh, Manu, Murad, Yanal M, Jia, William Wei-Guo

“…The development of effective cancer vaccines remains a significant challenge due to immune tolerance and limited clinical benefits. Oncolytic herpes simplex…”
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Cytotoxic effect of menadione and sodium orthovanadate in combination on human glioma cells by Delwar, Zahid M., Avramidis, Dimitrios, Follin, Elna, Hua, Yan, Siden, Åke, Cruz, Mabel, Paulsson, Kajsa M., Yakisich, Juan Sebastian

“…Summary Gliomas are the most common primary brain tumor, and their treatment is still a challenge. Here, we evaluated the antiproliferative effect of a novel…”
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Pankiller effect of prolonged exposure to menadione on glioma cells: potentiation by vitamin C by Vita, Marina F., Nagachar, Nivedita, Avramidis, Dimitrios, Delwar, Zahid M., Cruz, Mabel H., Siden, Åke, Paulsson, Kajsa M., Yakisich, Juan Sebastian

“…Summary Menadione (Vitamin K3) has anti-tumoral effects against a wide range of cancer cells. Its potential toxicity to normal cells and narrow therapeutic…”
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In vitro inhibition of topoisomerase IIα by reduced glutathione by Delwar, Zahid M, Vita, Marina Fernanda, Siden, Åke, Cruz, Mabel, Yakisich, Juan Sebastian

“…In most cells, the major intracellular redox buffer is glutathione (GSH) and its disulfide-oxidized (GSSG) form. The GSH/GSSG system maintains the…”
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Menadione  :  Sodium Orthovanadate Combination Eliminates and Inhibits Migration of Detached Cancer Cells by Delwar, Zahid M., Siden, Åke, Cruz, Mabel H., Yakisich, Juan Sebastian

“…Exposure of cancer cells to anticancer agents in cultures induces detachment of cells that are usually considered dead. These drug-induced detached cells…”
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A TRAMP‐derived orthotopic prostate syngeneic (TOPS) cancer model for investigating anti‐tumor treatments by Lardizabal, Justin, Ding, Jun, Delwar, Zahid, Rennie, Paul S., Jia, William

“…Background Patients with advanced prostate cancer have limited curative options, therefore new treatments are needed. Mouse models play a pivotal role in the…”
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Oncolytic virotherapy for urological cancers by Delwar, Zahid, Zhang, Kaixin, Rennie, Paul S., Jia, William

“…Key Points Oncolytic virotherapy is a cancer treatment that employs replication-competent viruses, which specifically infect, replicate in and lyse malignant…”
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Abstract 5641: Synergy of immunomodulators delivered by an HSV-1 oncolytic virus can enhance its therapeutic effects in vivo by Murad, Yanal M., Ding, Jun, Chouljenko, Dmitry, Lee, Erica, Bu, Luke, Liu, Guoyu, Zhao, Ronghua, Delwar, Zahid, Liu, Will, Jia, William

“…Oncolytic HSV-1 (oHSV-1) are among the most promising therapies for cancer. Besides the oncolytic activity delivered by the virus against tumor cells, this…”
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Abstract 5205: VG2025: Transcriptional and translational dually regulated (TTDR) oncolytic virus for cancer immunotherapy by Murad, Yanal, Liu, Guoyu, Lee, I-Fang, Delwar, Zahid, Chouljenko, Dmitry, Liu, Will, Ding, Jun, Bu, Luke, Zhao, Ronghua, Jia, William

“…VG2025 is a genetically modified HSV-1 oncolytic virus (OV) wherein the transcription and translation of critical viral genes are regulated to enhance virus…”
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A comparative study of thyroid hormone levels in young diabetic and non-diabetic patients by Islam, Sufia, Delwar, Zahid Mohammad, Khan, Shahidul Alam, Yesmine, Saquiba

“…Thyroid disorders can adversely affect diabetes control. The aim of the study was to compare thyroid hormone levels in type 1 diabetic patients with that of…”
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The Stemness Phenotype Model by Cruz, Mabel H., Siden, Åke, Calaf, Gloria M., Delwar, Zahid M., Yakisich, Juan Sebastian

“…The identification of a fraction of cancer stem cells (CSCs) associated with resistance to chemotherapy in most solid tumors leads to the dogma that…”
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