Search Results - "Delvenne, Philippe"

Neutrophil extracellular traps infiltrate the lung airway, interstitial, and vascular compartments in severe COVID-19 by Radermecker, Coraline, Detrembleur, Nancy, Guiot, Julien, Cavalier, Etienne, Henket, Monique, d'Emal, Céline, Vanwinge, Céline, Cataldo, Didier, Oury, Cécile, Delvenne, Philippe, Marichal, Thomas

“…Infection with SARS-CoV-2 is causing a deadly and pandemic disease called coronavirus disease-19 (COVID-19). While SARS-CoV-2-triggered hyperinflammatory…”
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SARS-CoV-2 in carotid body by Lambermont, Bernard, Davenne, Eric, Maclot, François, Delvenne, Philippe

“…A 42-year-old man was admitted to the intensive care unit in October 2020 for coronavirus disease-19 (COVID-19)-related acute respiratory distress syndrome…”
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Tumor microenvironment converts plasmacytoid dendritic cells into immunosuppressive/tolerogenic cells: insight into the molecular mechanisms by Demoulin, Stéphanie, Herfs, Michael, Delvenne, Philippe, Hubert, Pascale

“…Review of neoplastic lesions associated with infiltration of immunosuppressive pDC and the molecular pathways developed by tumors, to prevent antitumoral pDC…”
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FDG PET/CT radiomics for predicting the outcome of locally advanced rectal cancer by Lovinfosse, Pierre, Polus, Marc, Van Daele, Daniel, Martinive, Philippe, Daenen, Frédéric, Hatt, Mathieu, Visvikis, Dimitris, Koopmansch, Benjamin, Lambert, Frédéric, Coimbra, Carla, Seidel, Laurence, Albert, Adelin, Delvenne, Philippe, Hustinx, Roland

“…Purpose The aim of this study was to investigate the prognostic value of baseline 18 F-FDG PET/CT textural analysis in locally-advanced rectal cancer (LARC)…”
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Transforming growth factor beta‐induced, an extracellular matrix interacting protein, enhances glycolysis and promotes pancreatic cancer cell migration by Costanza, Brunella, Rademaker, Gilles, Tiamiou, Assia, De Tullio, Pascal, Leenders, Justine, Blomme, Arnaud, Bellier, Justine, Bianchi, Elettra, Turtoi, Andrei, Delvenne, Philippe, Bellahcène, Akeila, Peulen, Olivier, Castronovo, Vincent

“…Pancreatic ductal adenocarcinoma (PDAC) remains a deadly malignancy with no efficient therapy available up‐to‐date. Glycolysis is the main provider of…”
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PEGylation of lipoplexes: The right balance between cytotoxicity and siRNA effectiveness by Lechanteur, Anna, Furst, Tania, Evrard, Brigitte, Delvenne, Philippe, Hubert, Pascale, Piel, Géraldine

“…The delivery of small interfering RNA (siRNA) is an attractive therapeutic approach to treat several pathologies, such as viral infections or cancers. However,…”
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Clinical utility of an epigenetic assay to detect occult prostate cancer in histopathologically negative biopsies: results of the MATLOC study by Stewart, Grant D, Van Neste, Leander, Delvenne, Philippe, Delrée, Paul, Delga, Agnès, McNeill, S Alan, O'Donnell, Marie, Clark, James, Van Criekinge, Wim, Bigley, Joseph, Harrison, David J

“…Concern about possible false-negative prostate biopsy histopathology findings often leads to rebiopsy. A quantitative methylation specific polymerase chain…”
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Extracellular HMGB1 blockade inhibits tumor growth through profoundly remodeling immune microenvironment and enhances checkpoint inhibitor-based immunotherapy by Hubert, Pascale, Roncarati, Patrick, Demoulin, Stephanie, Pilard, Charlotte, Ancion, Marie, Reynders, Celia, Lerho, Thomas, Bruyere, Diane, Lebeau, Alizee, Radermecker, Coraline, Meunier, Margot, Nokin, Marie-Julie, Hendrick, Elodie, Peulen, Olivier, Delvenne, Philippe, Herfs, Michael

“…BackgroundHigh-mobility group box 1 (HMGB1) is a multifunctional redox-sensitive protein involved in various intracellular (eg, chromatin remodeling,…”
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Asporin Is a Fibroblast-Derived TGF-β1 Inhibitor and a Tumor Suppressor Associated with Good Prognosis in Breast Cancer by Maris, Pamela, Blomme, Arnaud, Palacios, Ana Perez, Costanza, Brunella, Bellahcène, Akeila, Bianchi, Elettra, Gofflot, Stephanie, Drion, Pierre, Trombino, Giovanna Elvi, Di Valentin, Emmanuel, Cusumano, Pino G, Maweja, Sylvie, Jerusalem, Guy, Delvenne, Philippe, Lifrange, Eric, Castronovo, Vincent, Turtoi, Andrei

“…Breast cancer is a leading malignancy affecting the female population worldwide. Most morbidity is caused by metastases that remain incurable to date. TGF-β1…”
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Mechanisms of cell entry by human papillomaviruses: an overview by Horvath, Caroline A J, Boulet, Gaëlle A V, Renoux, Virginie M, Delvenne, Philippe O, Bogers, John-Paul J

“…As the primary etiological agents of cervical cancer, human papillomaviruses (HPVs) must deliver their genetic material into the nucleus of the target cell…”
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Proteins involved in the endoplasmic reticulum stress are modulated in synovitis of osteoarthritis, chronic pyrophosphate arthropathy and rheumatoid arthritis, and correlate with the histological inflammatory score by de Seny, Dominique, Bianchi, Elettra, Baiwir, Dominique, Cobraiville, Gaël, Collin, Charlotte, Deliège, Mégane, Kaiser, Marie-Joëlle, Mazzucchelli, Gabriel, Hauzeur, Jean-Philippe, Delvenne, Philippe, Malaise, Michel G.

“…It is now well recognized that osteoarthritis (OA) synovial membrane presents inflammatory components. The aim of this work is to provide evidence that similar…”
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Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis by Nokin, Marie-Julie, Durieux, Florence, Peixoto, Paul, Chiavarina, Barbara, Peulen, Olivier, Blomme, Arnaud, Turtoi, Andrei, Costanza, Brunella, Smargiasso, Nicolas, Baiwir, Dominique, Scheijen, Jean L, Schalkwijk, Casper G, Leenders, Justine, De Tullio, Pascal, Bianchi, Elettra, Thiry, Marc, Uchida, Koji, Spiegel, David A, Cochrane, James R, Hutton, Craig A, De Pauw, Edwin, Delvenne, Philippe, Belpomme, Dominique, Castronovo, Vincent, Bellahcène, Akeila

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HMGB1 secretion during cervical carcinogenesis promotes the acquisition of a tolerogenic functionality by plasmacytoid dendritic cells by Demoulin, Stéphanie, Herfs, Michael, Somja, Joan, Roncarati, Patrick, Delvenne, Philippe, Hubert, Pascale

“…Acquisition of an impaired functionality by plasmacytoid dendritic cells (pDCs) contributing to cancer progression has been documented in different types of…”
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Dual-specificity phosphatase 3 deletion promotes obesity, non-alcoholic steatohepatitis and hepatocellular carcinoma by Jacques, Sophie, Arjomand, Arash, Perée, Hélène, Collins, Patrick, Mayer, Alice, Lavergne, Arnaud, Wéry, Marie, Mni, Myriam, Hego, Alexandre, Thuillier, Virginie, Becker, Guillaume, Bahri, Mohamed Ali, Plenevaux, Alain, Di Valentin, Emmanuel, Oury, Cécile, Moutschen, Michel, Delvenne, Philippe, Paquot, Nicolas, Rahmouni, Souad

“…Non-alcoholic fatty liver disease (NAFLD) is the most common chronic hepatic pathology in Western countries. It encompasses a spectrum of conditions ranging…”
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A laser microdissection-based workflow for FFPE tissue microproteomics: Important considerations for small sample processing by Longuespée, Rémi, Alberts, Deborah, Pottier, Charles, Smargiasso, Nicolas, Mazzucchelli, Gabriel, Baiwir, Dominique, Kriegsmann, Mark, Herfs, Michael, Kriegsmann, Jörg, Delvenne, Philippe, De Pauw, Edwin

“…[Display omitted] •We designed a workflow for microproteomics of laser-microdissected FFPE tissues.•We identified about 1400 proteins from 2700 breast cancer…”
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Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases by Blomme, Arnaud, Van Simaeys, Gaetan, Doumont, Gilles, Costanza, Brunella, Bellier, Justine, Otaka, Yukihiro, Sherer, Félicie, Lovinfosse, Pierre, Boutry, Sébastien, Palacios, Ana Perez, De Pauw, Edwin, Hirano, Touko, Yokobori, Takehiko, Hustinx, Roland, Bellahcène, Akeila, Delvenne, Philippe, Detry, Olivier, Goldman, Serge, Nishiyama, Masahiko, Castronovo, Vincent, Turtoi, Andrei

“…Cancer research is increasingly dependent of patient-derived xenograft model (PDX). However, a major point of concern regarding the PDX model remains the…”
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Methylglyoxal, a glycolysis metabolite, triggers metastasis through MEK/ERK/SMAD1 pathway activation in breast cancer by Nokin, Marie-Julie, Bellier, Justine, Durieux, Florence, Peulen, Olivier, Rademaker, Gilles, Gabriel, Maude, Monseur, Christine, Charloteaux, Benoit, Verbeke, Lieven, van Laere, Steven, Roncarati, Patrick, Herfs, Michael, Lambert, Charles, Scheijen, Jean, Schalkwijk, Casper, Colige, Alain, Caers, Jo, Delvenne, Philippe, Turtoi, Andrei, Castronovo, Vincent, Bellahcène, Akeila

“…Elevated aerobic glycolysis rate is a biochemical alteration associated with malignant transformation and cancer progression. This metabolic shift unavoidably…”
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PCIP-seq: simultaneous sequencing of integrated viral genomes and their insertion sites with long reads by Artesi, Maria, Hahaut, Vincent, Cole, Basiel, Lambrechts, Laurens, Ashrafi, Fereshteh, Marçais, Ambroise, Hermine, Olivier, Griebel, Philip, Arsic, Natasa, van der Meer, Frank, Burny, Arsène, Bron, Dominique, Bianchi, Elettra, Delvenne, Philippe, Bours, Vincent, Charlier, Carole, Georges, Michel, Vandekerckhove, Linos, Van den Broeke, Anne, Durkin, Keith

“…The integration of a viral genome into the host genome has a major impact on the trajectory of the infected cell. Integration location and variation within the…”
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Correction: Methylglyoxal, a glycolysis side-product, induces Hsp90 glycation and YAP-mediated tumor growth and metastasis by Nokin, Marie-Julie, Durieux, Florence, Peixoto, Paul, Chiavarina, Barbara, Peulen, Olivier, Blomme, Arnaud, Turtoi, Andrei, Costanza, Brunella, Smargiasso, Nicolas, Baiwir, Dominique, Scheijen, Jean L, Schalkwijk, Casper G, Leenders, Justine, De Tullio, Pascal, Bianchi, Elettra, Thiry, Marc, Uchida, Koji, Spiegel, David A, Cochrane, James R, Hutton, Craig A, De Pauw, Edwin, Delvenne, Philippe, Belpomme, Dominique, Castronovo, Vincent, Bellahcène, Akeila

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Xenogeneic Graft-Versus-Host Disease in Humanized NSG and NSG-HLA-A2/HHD Mice by Ehx, Grégory, Somja, Joan, Warnatz, Hans-Jörg, Ritacco, Caroline, Hannon, Muriel, Delens, Loïc, Fransolet, Gilles, Delvenne, Philippe, Muller, Joséphine, Beguin, Yves, Lehrach, Hans, Belle, Ludovic, Humblet-Baron, Stéphanie, Baron, Frédéric

“…Despite the increasing use of humanized mouse models to study new approaches of graft-versus-host disease (GVHD) prevention, the pathogenesis of xenogeneic…”
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