Search Results - "Delvendahl, Igor"
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Efficient sampling-based Bayesian Active Learning for synaptic characterization
Published in PLoS computational biology (01-08-2023)“…Bayesian Active Learning (BAL) is an efficient framework for learning the parameters of a model, in which input stimuli are selected to maximize the mutual…”
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Ultrafast action potentials mediate kilohertz signaling at a central synapse
Published in Neuron (Cambridge, Mass.) (01-10-2014)“…Fast synaptic transmission is important for rapid information processing. To explore the maximal rate of neuronal signaling and to analyze the presynaptic…”
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3
Dysbindin links presynaptic proteasome function to homeostatic recruitment of low release probability vesicles
Published in Nature communications (18-01-2018)“…Here we explore the relationship between presynaptic homeostatic plasticity and proteasome function at the Drosophila neuromuscular junction. First, we…”
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How to maintain active zone integrity during high-frequency transmission
Published in Neuroscience research (01-02-2018)“…•Presynaptic vesicle fusion disrupts the structural integrity of the active zone (AZ).•Several mechanisms potentially maintain AZ integrity during synaptic…”
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5
GluA4 facilitates cerebellar expansion coding and enables associative memory formation
Published in eLife (05-07-2021)“…AMPA receptors (AMPARs) mediate excitatory neurotransmission in the central nervous system (CNS) and their subunit composition determines synaptic efficacy…”
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Editorial: Methods and applications in cellular neurophysiology
Published in Frontiers in cellular neuroscience (10-03-2023)Get full text
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7
Reduced endogenous Ca²⁺ buffering speeds active zone Ca²⁺ signaling
Published in Proceedings of the National Academy of Sciences - PNAS (09-06-2015)“…Fast synchronous neurotransmitter release at the presynaptic active zone is triggered by local Ca²⁺ signals, which are confined in their spatiotemporal extent…”
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Gradients in the mammalian cerebellar cortex enable Fourier-like transformation and improve storing capacity
Published in eLife (05-02-2020)“…Cerebellar granule cells (GCs) make up the majority of all neurons in the vertebrate brain, but heterogeneities among GCs and potential functional consequences…”
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The role of pulse shape in motor cortex transcranial magnetic stimulation using full-sine stimuli
Published in PloS one (16-12-2014)“…A full-sine (biphasic) pulse waveform is most commonly used for repetitive transcranial magnetic stimulation (TMS), but little is known about how variations in…”
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Dendritic patch-clamp recordings from cerebellar granule cells demonstrate electrotonic compactness
Published in Frontiers in cellular neuroscience (19-03-2015)“…Cerebellar granule cells (GCs), the smallest neurons in the brain, have on average four short dendrites that receive high-frequency mossy fiber inputs…”
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Influence of Waveform and Current Direction on Short-Interval Intracortical Facilitation: A Paired-Pulse TMS Study
Published in Brain stimulation (2014)“…Abstract Background Transcranial magnetic stimulation (TMS) of the human primary motor hand area (M1-HAND) can produce multiple descending volleys in…”
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Occlusion of bidirectional plasticity by preceding low-frequency stimulation in the human motor cortex
Published in Clinical neurophysiology (01-04-2010)“…Abstract Objective Low-frequency stimulation, which does not induce long-term potentiation (LTP) or long-term potentiation (LTD) by itself, suppresses…”
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Plasticity of motor threshold and motor-evoked potential amplitude – A model of intrinsic and synaptic plasticity in human motor cortex?
Published in Brain stimulation (01-10-2012)“…Abstract Background Neuronal plasticity is the physiological correlate of learning and memory. In animal experiments, synaptic (i.e. long-term potentiation…”
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Transcranial magnetic stimulation with a half-sine wave pulse elicits direction-specific effects in human motor cortex
Published in BMC neuroscience (05-11-2012)“…Transcranial magnetic stimulation (TMS) commonly uses so-called monophasic pulses where the initial rapidly changing current flow is followed by a critically…”
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The Cerebellar Mossy Fiber Synapse as a Model for High-Frequency Transmission in the Mammalian CNS
Published in Trends in neurosciences (Regular ed.) (01-11-2016)“…The speed of neuronal information processing depends on neuronal firing frequency. Here, we describe the evolutionary advantages and ubiquitous occurrence of…”
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The time course of motor cortex plasticity after spaced motor practice
Published in Brain stimulation (01-07-2011)“…Background Motor learning takes place in several phases. Animal experiments suggest that synaptic plasticity plays an important role in acquisition of motor…”
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Rapid and sustained homeostatic control of presynaptic exocytosis at a central synapse
Published in Proceedings of the National Academy of Sciences - PNAS (19-11-2019)“…Animal behavior is remarkably robust despite constant changes in neural activity. Homeostatic plasticity stabilizes central nervous system (CNS) function on…”
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Homeostatic plasticity—a presynaptic perspective
Published in Current opinion in neurobiology (01-02-2019)“…•Homeostatic signaling regulates-specific presynaptic mechanisms.•Work in Drosophila has implicated several genes in presynaptic homeostatic…”
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Fast, Temperature-Sensitive and Clathrin-Independent Endocytosis at Central Synapses
Published in Neuron (Cambridge, Mass.) (04-05-2016)“…The fusion of neurotransmitter-filled vesicles during synaptic transmission is balanced by endocytotic membrane retrieval. Despite extensive research, the…”
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Two types of exercise‐induced neuroplasticity in congenital hemiparesis: a transcranial magnetic stimulation, functional MRI, and magnetoencephalography study
Published in Developmental medicine and child neurology (01-10-2013)“…Aim Early unilateral brain lesions can lead to a persistence of ipsilateral corticospinal projections from the contralesional hemisphere, which can enable the…”
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