Search Results - "Delva, Luisette"

Monoclonal antibody exposure in rat and cynomolgus monkey cerebrospinal fluid following systemic administration by Wang, Qin, Delva, Luisette, Weinreb, Paul H, Pepinsky, Robert B, Graham, Danielle, Veizaj, Elvana, Cheung, Anne E, Chen, Weiping, Nestorov, Ivan, Rohde, Ellen, Caputo, Robin, Kuesters, Geoffrey M, Bohnert, Tonika, Gan, Liang-Shang

“…Many studies have focused on the challenges of small molecule uptake across the blood-brain barrier, whereas few in-depth studies have assessed the challenges…”
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Discovery and Preclinical Characterization of BIIB091, a Reversible, Selective BTK Inhibitor for the Treatment of Multiple Sclerosis by Hopkins, Brian T, Bame, Eris, Bajrami, Bekim, Black, Cheryl, Bohnert, Tonika, Boiselle, Carrie, Burdette, Doug, Burns, Jeremy C, Delva, Luisette, Donaldson, Douglas, Grater, Richard, Gu, Chungang, Hoemberger, Marc, Johnson, Josh, Kapadnis, Sudarshan, King, Kris, Lulla, Mukesh, Ma, Bin, Marx, Isaac, Magee, Tom, Meissner, Robert, Metrick, Claire M, Mingueneau, Michael, Murugan, Paramasivam, Otipoby, Kevin L, Polack, Evelyne, Poreci, Urjana, Prince, Robin, Roach, Allie M, Rowbottom, Chris, Santoro, Joseph C, Schroeder, Patricia, Tang, Hao, Tien, Eric, Zhang, Fengmei, Lyssikatos, Joseph

“…Multiple Sclerosis is a chronic autoimmune neurodegenerative disorder of the central nervous system (CNS) that is characterized by inflammation, demyelination,…”
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A cytosolic calcium transient is not necessary for degranulation or oxidative burst in immune complex-stimulated neutrophils by Seetoo, Kurt F., Schonhorn, Jeremy E., Gewirtz, Andrew T., Zhou, Ming Jie, McMenamin, Mary E., Delva, Luisette, Simons, Elizabeth R.

“…Receptor‐mediated activation of neutrophils (PMN) initiates possibly interdependent events, including a rapid transient increase in [Ca2+]i, implicated as a…”
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