Search Results - "Delpiccolo, Carina M. L"

Palladium-Catalyzed Cross-Coupling Reactions of Arylsiloxanes with Aryl Halides: Application to Solid-Supported Organic Synthesis by Traficante, Carla I, Delpiccolo, Carina M. L, Mata, Ernesto G

“…The solid-phase version of the Pd-catalyzed Hiyama reaction between a variety of aryltriethoxysilanes and immobilized aryl halides was developed. Smooth…”
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Antiangiogenic activity of the penicillin derivative TAP7f in melanoma by Barrionuevo, Elizabeth, Cornier, Patricia G., Delpiccolo, Carina M. L., Mata, Ernesto G., Roguin, Leonor P., Blank, Viviana C.

“…Previously , we demonstrated that the non-antibiotic penicillin derivative TAP7f inhibited melanoma metastasis in vitro and in vivo through the downregulation…”
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Synergistic antitumor effect of a penicillin derivative combined with thapsigargin in melanoma cells by Bellizzi, Yanina, Cornier, Patricia G., Delpiccolo, Carina M. L., Mata, Ernesto G., Blank, Viviana, Roguin, Leonor P.

“…Purpose To investigate the effect of TAP7f, a penicillin derivative previously characterized as a potent antitumor agent that promotes ER stress and apoptosis,…”
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Contribution of endoplasmic reticulum stress, MAPK and PI3K/Akt pathways to the apoptotic death induced by a penicillin derivative in melanoma cells by Bellizzi, Yanina, Anselmi Relats, Juan Manuel, Cornier, Patricia G., Delpiccolo, Carina M. L., Mata, Ernesto G., Cayrol, Florencia, Cremaschi, Graciela A., Blank, Viviana C., Roguin, Leonor P.

“…We have previously examined the in vitro and in vivo antitumor action of TAP7f, a synthetic triazolylpeptidyl penicillin, on murine melanoma cells. In this…”
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Design of a Selective Ring-Closing Enyne Metathesis–Reduction for the Generation of Different Synthetic Scaffolds by Prada Gori, Denis N, Permingeat Squizatto, Caterina, Cornier, Patricia G, Delpiccolo, Carina M. L

“…A tandem process of ring-closing enyne metathesis (RCEYM)–reduction using modern ruthenium catalysts and a hydrogen donor is described. This straightforward…”
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A Penicillin Derivative Exerts an Anti-Metastatic Activity in Melanoma Cells Through the Downregulation of Integrin αvβ3 and Wnt/β-Catenin Pathway by Barrionuevo, Elizabeth, Cayrol, Florencia, Cremaschi, Graciela A, Cornier, Patricia G, Boggián, Dora B, Delpiccolo, Carina M L, Mata, Ernesto G, Roguin, Leonor P, Blank, Viviana C

“…The synthetic triazolylpeptidyl penicillin derivative, named TAP7f, has been previously characterized as an effective antitumor agent and against B16-F0…”
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Chemoselective and Sequential Palladium-Catalyzed Couplings for the Generation of Stilbene Libraries via Immobilized Substrates by Traficante, Carla I, Fagundez, Catherine, Serra, Gloria L, Mata, Ernesto G, Delpiccolo, Carina M. L

“…A versatile palladium-catalyzed tandem synthetic sequence to afford E-stilbenes libraries has been developed. Excellent regio- and stereocontrol have been…”
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Unprecedented Multifunctionality of Grubbs and Hoveyda–Grubbs Catalysts: Competitive Isomerization, Hydrogenation, Silylation and Metathesis Occurring in Solution and on Solid Phase by Maitena Martinez-Amezaga, Carina M. L. Delpiccolo, Luciana Méndez, Ileana Dragutan, Valerian Dragutan, Ernesto G. Mata

“…This contribution showcases the interplay of several non-metathetic reactions (isomerization, silylation and “hydrogen-free” reduction) with metathesis in…”
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Synthesis of 2,3-Dihydropyrroles by Rhodium(II)-Catalyzed Transannulation of N -Sulfonyl-1,2,3-triazoles: Diversity Generation by One-Pot Methodologies by Permingeat Squizatto, Caterina, Bianchini, Maira A., Delpiccolo, Carina M.L.

“…A versatile one-pot strategy for the generation of compounds of synthetic interest has been presented, promoting the development of practical processes. First,…”
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Transition Metal‐Catalyzed Reactions and Solid‐Phase Synthesis: A Convenient Blend by Cornier, Patricia G., Delpiccolo, Carina M. L., Martiren, Nadia L., Mata, Ernesto G., Mendez, Luciana, Squizatto, Caterina Permingeat, Pizzio, Marianela G.

“…Transition metal‐catalyzed, C−C and C−N bond‐forming reactions have made an enormous impact in the way complex molecules are assembled. The benefits of…”
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Synthetic Strategies towards the Generation of Penicillin-Containing Hybrids in the Search for Anticancer Activity by Martiren, Nadia L, Bajicoff, Sofía, Bellizzi, Yanina, Blank, Viviana, Roguin, Leonor, Cornier, Patricia, Mata, Ernesto G, Delpiccolo, Carina

“…An extended library of hybrids that combined a penicillin derivative with a peptoid moiety was designed and synthetized using either a solid-phase or a mixed…”
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A novel penicillin derivative induces antitumor effect in melanoma cells by Blank, Viviana, Bellizzi, Yanina, Zotta, Elsa, Cornier, Patricia G, Delpiccolo, Carina M.L, Boggián, Dora B, Mata, Ernesto G, Roguin, Leonor P

“…In this study, we explored the in-vitro and in-vivo mechanism of antitumor action of a novel synthetic nonantibiotic triazolylpeptidyl penicillin derivative,…”
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Solid-phase based synthesis of biologically promising triazolyl aminoacyl (peptidyl) penicillins by Cornier, Patricia G., Boggián, Dora B., Mata, Ernesto G., Delpiccolo, Carina M.L.

“…An efficient and versatile methodology for the preparation of valuable triazolyl aminoacyl (peptidyl) penicillins is described. Solid-phase Cu(I)-catalyzed…”
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An Efficient, Stereoselective Solid-Phase Synthesis of β-Lactams Using Mukaiyama's Salt for the Staudinger Reaction by Delpiccolo, Carina M. L, Fraga, M. Amelia, Mata, Ernesto G

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Exploring the Solid-Phase Synthesis of 3,4-Disubstituted β-Lactams:  Scope and Limitations by Delpiccolo, Carina M. L, Méndez, Luciana, Fraga, M. Amelia, Mata, Ernesto G

“…This work describes a comprehensive study on the solid-phase synthesis of 3,4-disubstituted β-lactams. In situ generated ketenes react with immobilized…”
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Cover Feature: Transition Metal‐Catalyzed Reactions and Solid‐Phase Synthesis: A Convenient Blend (Eur. J. Org. Chem. 38/2022) by Cornier, Patricia G., Delpiccolo, Carina M. L., Martiren, Nadia L., Mata, Ernesto G., Mendez, Luciana, Squizatto, Caterina Permingeat, Pizzio, Marianela G.

“…The Cover Feature represents the “factory of molecules” using transition‐metal catalysis on solid‐phase synthesis. The transition metals are responsible for…”
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Solid-phase Petasis multicomponent reaction for the generation of β-lactams 3-substituted with non-proteinogenic α-amino acids by Cornier, Patricia G., Delpiccolo, Carina M.L., Boggián, Dora B., Mata, Ernesto G.

“…An efficient protocol for the rapid generation of libraries of biologically promising β-lactams is described. Key step is a solid-phase based multicomponent…”
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Garbage in, garbage out: how reliable training data improved a virtual screening approach against SARS-CoV-2 MPro by Ruatta, Santiago M, Prada Gori, Denis N, Fló Díaz, Martín, Lorenzelli, Franca, Perelmuter, Karen, Alberca, Lucas N, Bellera, Carolina L, Medeiros, Andrea, López, Gloria V, Ingold, Mariana, Porcal, Williams, Dibello, Estefanía, Ihnatenko, Irina, Kunick, Conrad, Incerti, Marcelo, Luzardo, Martín, Colobbio, Maximiliano, Ramos, Juan Carlos, Manta, Eduardo, Minini, Lucía, Lavaggi, María Laura, Hernández, Paola, Šarlauskas, Jonas, Huerta García, César Sebastian, Castillo, Rafael, Hernández-Campos, Alicia, Ribaudo, Giovanni, Zagotto, Giuseppe, Carlucci, Renzo, Medrán, Noelia S, Labadie, Guillermo R, Martinez-Amezaga, Maitena, Delpiccolo, Carina M L, Mata, Ernesto G, Scarone, Laura, Posada, Laura, Serra, Gloria, Calogeropoulou, Theodora, Prousis, Kyriakos, Detsi, Anastasia, Cabrera, Mauricio, Alvarez, Guzmán, Aicardo, Adrián, Araújo, Verena, Chavarría, Cecilia, Mašič, Lucija Peterlin, Gantner, Melisa E, Llanos, Manuel A, Rodríguez, Santiago, Gavernet, Luciana, Park, Soonju, Heo, Jinyeong, Lee, Honggun, Paul Park, Kyu-Ho, Bollati-Fogolín, Mariela, Pritsch, Otto, Shum, David, Talevi, Alan, Comini, Marcelo A

“…The identification of chemical compounds that interfere with SARS-CoV-2 replication continues to be a priority in several academic and pharmaceutical…”
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Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β42 monomer by Gera, János, Szögi, Titanilla, Bozsó, Zsolt, Fülöp, Livia, Barrera, Exequiel E., Rodriguez, Ana M., Méndez, Luciana, Delpiccolo, Carina M.L., Mata, Ernesto G., Cioffi, Federica, Broersen, Kerensa, Paragi, Gabor, Enriz, Ricardo D.

“…[Display omitted] •A novel mimetic peptide that inhibits Aβ cytotoxicity at submicromolar concentration is reported.•Antiaggregant activities were measured…”
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Searching for improved mimetic peptides inhibitors preventing conformational transition of amyloid-β 42 monomer by Gera, János, Szögi, Titanilla, Bozsó, Zsolt, Fülöp, Livia, Barrera, Exequiel E, Rodriguez, Ana M, Méndez, Luciana, Delpiccolo, Carina M L, Mata, Ernesto G, Cioffi, Federica, Broersen, Kerensa, Paragi, Gabor, Enriz, Ricardo D

“…A series of novel mimetic peptides were designed, synthesised and biologically evaluated as inhibitors of Aβ aggregation. One of the synthesised peptidic…”
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