Search Results - "Delp, Scott"
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OpenSim Moco: Musculoskeletal optimal control
Published in PLoS computational biology (28-12-2020)“…Musculoskeletal simulations are used in many different applications, ranging from the design of wearable robots that interact with humans to the analysis of…”
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Flexing computational muscle: modeling and simulation of musculotendon dynamics
Published in Journal of biomechanical engineering (01-02-2013)“…Muscle-driven simulations of human and animal motion are widely used to complement physical experiments for studying movement dynamics. Musculotendon models…”
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Predicting gait adaptations due to ankle plantarflexor muscle weakness and contracture using physics-based musculoskeletal simulations
Published in PLoS computational biology (07-10-2019)“…Deficits in the ankle plantarflexor muscles, such as weakness and contracture, occur commonly in conditions such as cerebral palsy, stroke, muscular dystrophy,…”
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4
A Biomechanical Model of the Scapulothoracic Joint to Accurately Capture Scapular Kinematics during Shoulder Movements
Published in PloS one (06-01-2016)“…The complexity of shoulder mechanics combined with the movement of skin relative to the scapula makes it difficult to measure shoulder kinematics with…”
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5
An Open-Source and Wearable System for Measuring 3D Human Motion in Real-Time
Published in IEEE transactions on biomedical engineering (01-02-2022)“…Objective: Analyzing human motion is essential for diagnosing movement disorders and guiding rehabilitation for conditions like osteoarthritis, stroke, and…”
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6
Large-scale physical activity data reveal worldwide activity inequality
Published in Nature (London) (20-07-2017)“…A huge smartphone dataset of physical activity yields global insights, revealing that activity inequality predicts obesity better than does volume of activity…”
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Machine learning in human movement biomechanics: Best practices, common pitfalls, and new opportunities
Published in Journal of biomechanics (16-11-2018)“…Traditional laboratory experiments, rehabilitation clinics, and wearable sensors offer biomechanists a wealth of data on healthy and pathological movement. To…”
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A Brainstem-Spinal Cord Inhibitory Circuit for Mechanical Pain Modulation by GABA and Enkephalins
Published in Neuron (Cambridge, Mass.) (22-02-2017)“…Pain thresholds are, in part, set as a function of emotional and internal states by descending modulation of nociceptive transmission in the spinal cord…”
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Are subject-specific musculoskeletal models robust to the uncertainties in parameter identification?
Published in PloS one (12-11-2014)“…Subject-specific musculoskeletal modeling can be applied to study musculoskeletal disorders, allowing inclusion of personalized anatomy and properties…”
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10
Automatic real-time gait event detection in children using deep neural networks
Published in PloS one (31-01-2019)“…Annotation of foot-contact and foot-off events is the initial step in post-processing for most quantitative gait analysis workflows. If clean force plate…”
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Muscle contributions to fore-aft and vertical body mass center accelerations over a range of running speeds
Published in Journal of biomechanics (22-02-2013)“…Abstract Running is a bouncing gait in which the body mass center slows and lowers during the first half of the stance phase; the mass center is then…”
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Personalizing exoskeleton assistance while walking in the real world
Published in Nature (London) (13-10-2022)“…Personalized exoskeleton assistance provides users with the largest improvements in walking speed 1 and energy economy 2 – 4 but requires lengthy tests under…”
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13
Simulating ideal assistive devices to reduce the metabolic cost of walking with heavy loads
Published in PloS one (12-07-2017)“…Wearable robotic devices can restore and enhance mobility. There is growing interest in designing devices that reduce the metabolic cost of walking; however,…”
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14
Deep neural networks enable quantitative movement analysis using single-camera videos
Published in Nature communications (13-08-2020)“…Many neurological and musculoskeletal diseases impair movement, which limits people’s function and social participation. Quantitative assessment of motion is…”
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15
Muscle contributions to propulsion and support during running
Published in Journal of biomechanics (19-10-2010)“…Abstract Muscles actuate running by developing forces that propel the body forward while supporting the body’s weight. To understand how muscles contribute to…”
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Simulating Ideal Assistive Devices to Reduce the Metabolic Cost of Running
Published in PloS one (22-09-2016)“…Tools have been used for millions of years to augment the capabilities of the human body, allowing us to accomplish tasks that would otherwise be difficult or…”
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Men and women adopt similar walking mechanics and muscle activation patterns during load carriage
Published in Journal of biomechanics (27-09-2013)“…Abstract Although numerous studies have investigated the effects of load carriage on gait mechanics, most have been conducted on active military men. It…”
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Full-Body Musculoskeletal Model for Muscle-Driven Simulation of Human Gait
Published in IEEE transactions on biomedical engineering (01-10-2016)“…Objective: Musculoskeletal models provide a noninvasive means to study human movement and predict the effects of interventions on gait. Our goal was to create…”
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Optogenetic control of targeted peripheral axons in freely moving animals
Published in PloS one (21-08-2013)“…Optogenetic control of the peripheral nervous system (PNS) would enable novel studies of motor control, somatosensory transduction, and pain processing. Such…”
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Is my model good enough? Best practices for verification and validation of musculoskeletal models and simulations of movement
Published in Journal of biomechanical engineering (01-02-2015)“…Computational modeling and simulation of neuromusculoskeletal (NMS) systems enables researchers and clinicians to study the complex dynamics underlying human…”
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