Search Results - "Deloia, Julie A."

Differential gene expression identifies a transcriptional regulatory network involving ER-alpha and PITX1 in invasive epithelial ovarian cancer by Li, Yichao, Jaiswal, Sushil K, Kaur, Rupleen, Alsaadi, Dana, Liang, Xiaoyu, Drews, Frank, DeLoia, Julie A, Krivak, Thomas, Petrykowska, Hanna M, Gotea, Valer, Welch, Lonnie, Elnitski, Laura

“…Background The heterogeneous subtypes and stages of epithelial ovarian cancer (EOC) differ in their biological features, invasiveness, and response to…”
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Differential analysis of ovarian and endometrial cancers identifies a methylator phenotype by Kolbe, Diana L, DeLoia, Julie A, Porter-Gill, Patricia, Strange, Mary, Petrykowska, Hanna M, Guirguis, Alfred, Krivak, Thomas C, Brody, Lawrence C, Elnitski, Laura

“…Despite improved outcomes in the past 30 years, less than half of all women diagnosed with epithelial ovarian cancer live five years beyond their diagnosis…”
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Relationship Between ERCC1 Polymorphisms, Disease Progression, and Survival in the Gynecologic Oncology Group Phase III Trial of Intraperitoneal Versus Intravenous Cisplatin and Paclitaxel for Stage III Epithelial Ovarian Cancer by KRIVAK, Thomas C, DARCY, Kathleen M, CHUNQIAO TIAN, ARMSTRONG, Deborah, BAYSAL, Bora E, GALLION, Holly, AMBROSONE, Christine B, DELOIA, Julie A

“…We hypothesized that common polymorphisms in excision repair cross-complementation group 1 (ERCC1), involved in nucleotide excision repair of platinum-induced…”
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Monocytes are progressively activated in the circulation of pregnant women by Luppi, Patrizia, Haluszczak, Catherine, Betters, Dawn, Richard, Craig A. H., Trucco, Massimo, DeLoia, Julie A.

“…Pregnancy is characterized by the presence of generalized leukocyte activation. We used flow cytometry to investigate changes in phenotype and intracellular…”
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Noninvasive assessment of cell proliferation in ovarian cancer using [18 F] 3′deoxy-3-fluorothymidine positron emission tomography/computed tomography imaging by Richard, Scott D, Bencherif, Badreddine, Edwards, Robert P, Elishaev, Esther, Krivak, Thomas C, Mountz, James M, DeLoia, Julie A

“…Abstract Introduction Positron emission tomography (PET)/computed tomography (CT) imaging of suspected new and recurrent ovarian carcinoma was performed to…”
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Coordinate up-regulation of TMEM97 and cholesterol biosynthesis genes in normal ovarian surface epithelial cells treated with progesterone: implications for pathogenesis of ovarian cancer by Wilcox, Cathy B, Feddes, Grace O, Willett-Brozick, Joan E, Hsu, Lih-Ching, DeLoia, Julie A, Baysal, Bora E

“…Ovarian cancer (OvCa) most often derives from ovarian surface epithelial (OSE) cells. Several lines of evidence strongly suggest that increased exposure to…”
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Comparative Gene Expression Analysis of Ovarian Carcinoma and Normal Ovarian Epithelium by Serial Analysis of Gene Expression by PETERS, David G, KUDLA, Donna M, DELOIA, Julie A, TIAN JIAO CHU, FAIRFULL, Liane, EDWARDS, Robert P, FERRELL, Robert E

“…Despite the poor prognosis of ovarian cancer and the importance of early diagnosis, there are no reliable noninvasive biomarkers for detection in the early…”
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BRCA1/2 mutations and expression: Response to platinum chemotherapy in patients with advanced stage epithelial ovarian cancer by Dann, Rebecca Byler, DeLoia, Julie A, Timms, Kirsten M, Zorn, Kristin K, Potter, Jennifer, Flake, Darl D, Lanchbury, Jerry S, Krivak, Thomas C

“…Abstract Objective Our objective was to determine the rate of BRCA1/2 deficiency in platinum-sensitive and platinum-resistant tumors from a cohort of unselect…”
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Clinical use of combined positron emission tomography and computed tomography (FDG-PET/CT) in recurrent ovarian cancer by Thrall, Melissa M, DeLoia, Julie A, Gallion, Holly, Avril, Norbert

“…Abstract Objective The aim of this study was to evaluate the use of co-registered PET/CT using F-18 fluorodeoxyglucose (FDG) for surveillance and follow-up of…”
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Monocytes of preeclamptic women spontaneously synthesize pro-inflammatory cytokines by Luppi, Patrizia, DeLoia, Julie A.

“…The maternal syndrome preeclampsia is characterized by a generalized inflammatory response with activation of circulating leukocytes and altered levels of…”
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Common variants in ABCB1, ABCC2 and ABCG2 genes and clinical outcomes among women with advanced stage ovarian cancer treated with platinum and taxane-based chemotherapy: A Gynecologic Oncology Group study by Tian, Chunqiao, Ambrosone, Christine B, Darcy, Kathleen M, Krivak, Thomas C, Armstrong, Deborah K, Bookman, Michael A, Davis, Warren, Zhao, Hua, Moysich, Kirsten, Gallion, Holly, DeLoia, Julie A

“…Abstract Purpose Efflux transporters of the ATP-binding cassette (ABC) family are major determinants of chemoresistance in tumor cells. This study examined…”
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Recurrent patterns of DNA methylation in the ZNF154, CASP8, and VHL promoters across a wide spectrum of human solid epithelial tumors and cancer cell lines by Sánchez-Vega, Francisco, Gotea, Valer, Petrykowska, Hanna M, Margolin, Gennady, Krivak, Thomas C, DeLoia, Julie A, Bell, Daphne W, Elnitski, Laura

“…The study of aberrant DNA methylation in cancer holds the key to the discovery of novel biological markers for diagnostics and can help to delineate important…”
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Comparison of cell cycle regulatory gene mRNA in three different types of human trophoblasts and effect of transforming growth factor by Richard, Craig A. H., Jones, Jaqueline M., DeLoia, Julie A.

“…Aim:  Identifying the factors responsible for reducing the proliferation, syncytialization, and invasiveness of trophoblast tissues, as seen with preeclampsia,…”
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Comparison of ERCC1/XPF genetic variation, mRNA and protein levels in women with advanced stage ovarian cancer treated with intraperitoneal platinum by DeLoia, Julie A, Bhagwat, Nikhil R, Darcy, Kathleen M, Strange, Mary, Tian, Chunquio, Nuttall, Kevin, Krivak, Thomas C, Niedernhofer, Laura J

“…Abstract Objective Approximately 20% of patients receiving platinum-based chemotherapy for epithelial ovarian cancer (EOC) are refractory or develop early…”
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Single nucleotide polypmorphisms in ERCC1 are associated with disease progression, and survival in patients with advanced stage ovarian and primary peritoneal carcinoma; A Gynecologic Oncology Group Study by Krivak, Thomas C, Darcy, Kathleen M, Tian, Chunqiao, Bookman, Michael, Gallion, Holly, Ambrosone, Christine B, DeLoia, Julie A

“…Abstract Objective This study evaluated common polymorphisms in excision repair cross-complementation group 1 (ERCC1) involved in repair of platinum-induced…”
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Preeclampsia Activates Circulating Immune Cells with Engagement of the NF-κB Pathway by Luppi, Patrizia, Tse, Hubert, Lain, Kristine Y., Markovic, Nina, Piganelli, Jon D., DeLoia, Julie A.

“…Problem Compelling evidence implicates peripheral immune activation in the pathophysiology of preeclampsia. Polymorphonuclear neutrophils appear to be the…”
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Cigarette exposure induces changes in maternal vascular function in a pregnant mouse model by Gandley, Robin E, Jeyabalan, Arun, Desai, Ketaki, McGonigal, Stacy, Rohland, Jennifer, DeLoia, Julie A

“…Smoking is associated with multiple adverse pregnancy outcomes, including fetal growth restriction. The objective of this study was to determine whether…”
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BRCA1 expression in a large series of sporadic ovarian carcinomas: a Gynecologic Oncology Group study by Thrall, M, Gallion, H H, Kryscio, R, Kapali, M, Armstrong, D K, DeLoia, Julie A

“…BRCA1 is a tumor suppressor gene that, when mutated, is associated with the development of hereditary ovarian cancer. A role for BRCA1 in the pathoetiology of…”
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Use of gene expression profiles to stage concurrent endometrioid tumors of the endometrium and ovary by Guirguis, Alfred, Elishaev, Esther, Oh, Sung-Hee, Tseng, George C, Zorn, Kristin, DeLoia, Julie A

“…Abstract Objective. The objectives of this study were to determine whether there are distinct gene expression profiles for endometrial and ovarian endometrioid…”
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Centrosome abnormalities in ovarian cancer by Hsu, Lih‐Ching, Kapali, Malathy, DeLoia, Julie A., Gallion, Holly H.

“…Centrosome abnormalities have been found in various cancer types and are thought to be involved in early development of cancer and/or progression. The…”
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