Search Results - "Delmas, P"

European guidance for the diagnosis and management of osteoporosis in postmenopausal women by Kanis, J. A, Burlet, N, Cooper, C, Delmas, P. D, Reginster, J.-Y, Borgstrom, F, Rizzoli, R

“…Summary Guidance is provided in a European setting on the assessment and treatment of postmenopausal women with or at risk from osteoporosis. Introduction The…”
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The role of collagen in bone strength by VIGUET-CARRIN, S, GARNERO, P, DELMAS, P. D

“…Bone is a complex tissue of which the principal function is to resist mechanical forces and fractures. Bone strength depends not only on the quantity of bone…”
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Biochemical markers of bone turnover: potential use in the investigation and management of postmenopausal osteoporosis by Szulc, P., Delmas, P. D.

“…Introduction The aim was to analyse data on the use of biochemical bone turnover markers (BTM) in postmenopausal osteoporosis. Methods We carried out a…”
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Insights into Material and Structural Basis of Bone Fragility from Diseases Associated with Fractures: How Determinants of the Biomechanical Properties of Bone Are Compromised by Disease by Chavassieux, P, Seeman, E, Delmas, P. D

“…Minimal trauma fractures in bone diseases are the result of bone fragility. Rather than considering bone fragility as being the result of a reduced amount of…”
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Pathways modulating neural KCNQ/M (Kv7) potassium channels by Delmas, Patrick, Brown, David A

“…K(+) channels play a crucial role in regulating the excitability of neurons. Many K(+) channels are, in turn, regulated by neurotransmitters. One of the first…”
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Denosumab for Prevention of Fractures in Postmenopausal Women with Osteoporosis by Cummings, Steven R, Martin, Javier San, McClung, Michael R, Siris, Ethel S, Eastell, Richard, Reid, Ian R, Delmas, Pierre, Zoog, Holly B, Austin, Matt, Wang, Andrea, Kutilek, Stepan, Adami, Silvano, Zanchetta, Jose, Libanati, Cesar, Siddhanti, Suresh, Christiansen, Claus

“…In this trial, women between the ages of 60 and 90 with low bone mineral density received twice-yearly subcutaneous injections of denosumab, a fully human…”
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Relationship of Early Changes in Bone Resorption to the Reduction in Fracture Risk With Risedronate by Eastell, R, Barton, I, Hannon, Ra, Chines, A, Garnero, P, Delmas, Pd

“…Changes in the level of biochemical markers of bone resorption with risedronate treatment for osteoporosis were examined as a surrogate for the decrease in…”
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Daily and intermittent oral ibandronate normalize bone turnover and provide significant reduction in vertebral fracture risk: results from the BONE study by DELMAS, P. D, RECKER, R. R, CHESNUT, C. H, SKAG, A, STAKKESTAD, J. A, EMKEY, R, GILBRIDE, J, SCHIMMER, R. C, CHRISTIANSEN, C

“…Increasing evidence suggests that a high rate of bone turnover is associated with low bone mineral density (BMD) and is strongly linked to fracture risk…”
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Cross sectional evaluation of biochemical markers of bone, cartilage, and synovial tissue metabolism in patients with knee osteoarthritis: relations with disease activity and joint damage by Garnero, P, Piperno, M, Gineyts, E, Christgau, S, Delmas, P D, Vignon, E

“…OBJECTIVE To analyse the relations between the urinary levels of type II collagen C-telopeptide (CTX-II) and glucosyl-galactosyl pyridinoline (Glc-Gal-PYD)—two…”
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Associations of vitamin D status with bone mineral density, bone turnover, bone loss and fracture risk in healthy postmenopausal women. The OFELY study by Garnero, P, Munoz, F, Sornay-Rendu, E, Delmas, P.D

“…Abstract Introduction Vitamin D status is considered as an important determinant of bone health but supplementation trials with vitamin D3 have yielded…”
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Bone microdamage: a clinical perspective by Chapurlat, R. D, Delmas, P. D

“…Introduction Microdamage accumulation due to fatigue loading may lead to fracture. In addition, several studies using animal models have suggested in recent…”
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The Type I Collagen Fragments ICTP and CTX Reveal Distinct Enzymatic Pathways of Bone Collagen Degradation by Garnero, P, Ferreras, M, Karsdal, MA, Nicamhlaoibh, R, Risteli, J, Borel, O, Qvist, P, Delmas, PD, Foged, NT, Delaissé, JM

“…Bone resorption may generate collagen fragments such as ICTP and CTX, which can be quantified in serum and/or urine by using specific immunoassays, and which…”
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MUSIC-like estimation of direction of arrival for noncircular sources by Abeida, H., Delmas, J.-P.

“…This paper examines the asymptotic performance of MUSIC-like algorithms for estimating directions of arrival (DOA) of narrowband complex noncircular sources…”
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Severity of prevalent vertebral fractures and the risk of subsequent vertebral and nonvertebral fractures: results from the MORE trial by Delmas, P.D, Genant, H.K, Crans, G.G, Stock, J.L, Wong, M, Siris, E, Adachi, J.D

“…Prevalent vertebral fractures and baseline bone mineral density (BMD) predict subsequent fracture risk. The objective of this analysis is to examine whether…”
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Body mass index as a predictor of fracture risk : A meta-analysis by DE LAET, C, KANIS, J. A, MCCLOSKEY, E. V, MELLSTROM, D, MELTON, L. J, MEUNIER, P. J, POIS, H. A. P, REEVE, J, SILMAN, A, TENENHOUSE, A, ODEN, A, JOHANSON, H, JOHNELL, O, DELMAS, P, EISMAN, J. A, KROGER, H, FUJIWARA, S, GARNERO, P

“…Low body mass index (BMI) is a well-documented risk factor for future fracture. The aim of this study was to quantify this effect and to explore the…”
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Efficacy and tolerability of once-monthly oral ibandronate in postmenopausal osteoporosis: 2 year results from the MOBILE study by Reginster, J-Y, Adami, S, Lakatos, P, Greenwald, M, Stepan, J J, Silverman, S L, Christiansen, C, Rowell, L, Mairon, N, Bonvoisin, B, Drezner, M K, Emkey, R, Felsenberg, D, Cooper, C, Delmas, P D, Miller, P D

“…Background: Reducing bisphosphonate dosing frequency may improve suboptimal adherence to treatment and therefore therapeutic outcomes in postmenopausal…”
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A meta-analysis of previous fracture and subsequent fracture risk by Kanis, J.A, Johnell, O, De Laet, C, Johansson, H, Oden, A, Delmas, P, Eisman, J, Fujiwara, S, Garnero, P, Kroger, H, McCloskey, E.V, Mellstrom, D, Melton, L.J, Pols, H, Reeve, J, Silman, A, Tenenhouse, A

“…Previous fracture is a well-documented risk factor for future fracture. The aim of this study was to quantify this risk on an international basis and to…”
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Bisphosphonates alter trabecular bone collagen cross-linking and isomerization in beagle dog vertebra by Allen, M. R., Gineyts, E., Leeming, D. J., Burr, D. B., Delmas, P. D.

“…Summary Changes in organic matrix may contribute to the anti-fracture efficacy of anti-remodeling agents. Following one year of treatment in beagle dogs,…”
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The role of mineralization and organic matrix in the microhardness of bone tissue from controls and osteoporotic patients by Boivin, G, Bala, Y, Doublier, A, Farlay, D, Ste-Marie, L.G, Meunier, P.J, Delmas, P.D

“…Abstract Degree of mineralization of bone (DMB) is a major intrinsic determinant of bone strength at the tissue level but its contribution to the microhardness…”
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High bone turnover is associated with accelerated bone loss but not with increased fracture risk in men aged 50 and over: the prospective MINOS study by Szulc, P, Montella, A, Delmas, P D

“…The association of bone turnover markers (BTM) with bone loss and fracture risk in men is poorly studied. The morphological basis of such a relationship is…”
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