Search Results - "Della Morte, Elena"
-
1
Human Osteochondral Explants as an Ex Vivo Model of Osteoarthritis for the Assessment of a Novel Class of Orthobiologics
Published in Pharmaceutics (10-06-2022)“…Osteoarthritis (OA) is a highly prevalent joint disease still lacking effective treatments. Its multifactorial etiology hampers the development of relevant…”
Get full text
Journal Article -
2
Dynamics of Connexin 43 Down Modulation in Human Articular Chondrocytes Stimulated by Tumor Necrosis Factor Alpha
Published in International journal of molecular sciences (16-05-2022)“…Connexin 43 (Cx43) exerts pivotal functions in articular chondrocytes (CH). It is involved in the communication among cells and between cells and the…”
Get full text
Journal Article -
3
Connexin 43 Modulation in Human Chondrocytes, Osteoblasts and Cartilage Explants: Implications for Inflammatory Joint Disorders
Published in International journal of molecular sciences (01-08-2024)“…Connexin 43 (Cx43) is crucial for the development and homeostasis of the musculoskeletal system, where it plays multifaceted roles, including intercellular…”
Get full text
Journal Article -
4
Boosting the therapeutic potential of cell secretome against osteoarthritis: Comparison of cytokine-based priming strategies
Published in Biomedicine & pharmacotherapy (01-01-2024)“…The secretome, or conditioned medium (CM), from Mesenchymal Stem/stromal Cells (MSCs) has recently emerged as a promising cell-free therapeutic against…”
Get full text
Journal Article -
5
Towards Secretome Standardization: Identifying Key Ingredients of MSC-Derived Therapeutic Cocktail
Published in Stem cells international (2021)“…The therapeutic potential of the conditioned medium (CM) derived from MSCs (mesenchymal stem/stromal cells) in disparate medical fields, from immunology to…”
Get full text
Journal Article -
6
Cartilage responses to inflammatory stimuli and adipose stem/stromal cell-derived conditioned medium: Results from an ex vivo model
Published in Regenerative therapy (01-06-2024)“…Osteoarthritis (OA), a chronic inflammatory joint disorder, still lacks effective therapeutic interventions. Consequently, the development of convenient…”
Get full text
Journal Article -
7
Serum starvation affects mitochondrial metabolism of adipose-derived stem/stromal cells
Published in Cytotherapy (Oxford, England) (01-07-2023)“…A large part of mesenchymal stromal cell (MSC) regenerative and immunomodulatory action is mediated by paracrine signaling. Hence, an increasing body of…”
Get full text
Journal Article -
8
Lipidomics of Cell Secretome Combined with the Study of Selected Bioactive Lipids in an In Vitro Model of Osteoarthritis
Published in Stem cells translational medicine (21-09-2022)“…Analytical advancements in lipidomics have enabled large-scale investigations of lipid biology. Herein, we focused on four bioactive lipid families, namely…”
Get full text
Journal Article -
9