Search Results - "Dell’Omo, Giulia"
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Cancer-derived EVs show tropism for tissues at early stage of neoplastic transformation
Published in Nanotheranostics (Sydney, NSW) (2021)“…From the past decade, extracellular vesicles (EVs) have attracted considerable attention as tools for the selective delivery of anti-neoplastic drugs to cancer…”
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Nicotinamide in the prevention of breast cancer recurrences?
Published in Oncotarget (17-09-2019)Get full text
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Inhibition of SIRT1 deacetylase and p53 activation uncouples the anti-inflammatory and chemopreventive actions of NSAIDs
Published in British journal of cancer (05-03-2019)“…Background Nonsteroidal anti-inflammatory drugs (NSAIDs) have been proposed as chemopreventive agents for many tumours; however, the mechanism responsible for…”
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4
TGS1 mediates 2,2,7-trimethyl guanosine capping of the human telomerase RNA to direct telomerase dependent telomere maintenance
Published in Nature communications (28-04-2022)“…Pathways that direct the selection of the telomerase-dependent or recombination-based, alternative lengthening of telomere (ALT) maintenance pathway in cancer…”
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5
Q192R Paraoxonase (PON)1 Polymorphism, Insulin Sensitivity, and Endothelial Function in Essential Hypertensive Men
Published in Clinical Medicine Insights. Cardiology (01-01-2014)“…Aims Essential hypertension is characterized by increased reactive oxygen species (ROS) generation harmful for insulin sensitivity and nitric oxide…”
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Discovery and characterization of a new class of NAD+-independent SIRT1 activators
Published in Pharmacological research (01-08-2024)“…The activity of sirtuin 1 (SIRT1, a member of the NAD+-dependent deacetylases family) decreases during aging as NAD+ levels naturally decline, thus increasing…”
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Association between high-normal albuminuria and risk factors for cardiovascular and renal disease in essential hypertensive men
Published in American journal of kidney diseases (01-07-2002)“…Background: Microalbuminuria (overnight urinary albumin excretion [UAE] > 15 μg/min) is associated with cardiovascular risk factors and predicts morbid events…”
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Association between plasma gamma-glutamyltransferase fractions and metabolic syndrome among hypertensive patients
Published in Scientific reports (20-09-2017)“…Among the risk factors associated to metabolic syndrome (MetS), hypertension shows the highest prevalence in Italy. We investigated the relationship between…”
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Colorectal cancer patient-derived organoids and cell lines harboring ATRX and/or DAXX mutations lack Alternative Lengthening of Telomeres (ALT)
Published in Cell death & disease (09-02-2023)“…Telomere maintenance is necessary to maintain cancer cell unlimited viability. However, the mechanisms maintaining telomere length in colorectal cancer (CRC)…”
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α-Adducin and angiotensin-converting enzyme polymorphisms in hypertension: evidence for a joint influence on albuminuria
Published in Journal of hypertension (01-05-2006)“…BACKGROUNDA single-nucleotide polymorphism (Gly460Trp) within the α-adducin gene (ADD1) may influence several renal phenotypes, including salt sensitivity,…”
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11
Angiotensin II, tissue factor and the thrombotic paradox of hypertension
Published in Expert review of cardiovascular therapy (01-12-2010)“…Tissue factor (TF), the physiologic initiator of blood coagulation, may contribute to the increased risk of thrombotic complications that characterizes…”
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12
The vascular effects of doxazosin in hypertension complicated by metabolic syndrome
Published in Coronary artery disease (01-02-2005)“…AIMSTo evaluate the vascular effects of doxazosin, an alpha-1 antagonist, in hypertensive patients with metabolic syndrome in whom the drug has previously been…”
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P-201: The effects of doxazosin in non diabetic hypertensive patients with the metabolic syndrome. A comparison with chlortalidone
Published in American journal of hypertension (01-05-2003)“…Background: The metabolic syndrome, the phenotype of an underlying insulin resistant state, is frequent in essential hypertension and carries an additional…”
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P-202: The effect of doxazosin on endothelial function in non diabetic hypertensive patients with the metabolic syndrome. A comparison with chlortalidone
Published in American journal of hypertension (01-05-2003)“…Background: Improvement of endothelial function is an important end-point in the subset of hypertensive patients with metabolic syndrome, the phenotype of an…”
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15
Right ventricular dysfunction in early systemic hypertension: a tissue Doppler imaging study in patients with high-normal and mildly increased arterial blood pressure
Published in Journal of hypertension (01-03-2010)“…PURPOSETo analyze the relationship between increasing systemic blood pressure (BP) and right ventricular (RV) function. SUBJECTS AND METHODSNinety-eight…”
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Human vs. ChatGPT. Is it possible obtain comparable results in the analysis of a scientific systematic review?
Published in Recenti progressi in medicina (01-09-2024)“…There is growing interest in the use of ChatGPT in the writing and reviewing of scientific articles. In line with the nature of ChatGPT, we tested its…”
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P-60: Dihydropiridine calcium channel blockers and dependent edema: a comparison between amlodipine and lercanidipine in essential hypertensive patients
Published in American journal of hypertension (01-04-2002)“…Background: Dependent leg edema complicates treatment with amlodipine (AMLO) and other dihydropiridine (DHP) calcium channel blocker (CCB)s and frequently…”
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18
The laminA/NF-Y protein complex reveals an unknown transcriptional mechanism on cell proliferation
Published in Oncotarget (10-01-2017)“…Lamin A is a component of the nuclear matrix that also controls proliferation by largely unknown mechanisms. NF-Y is a ubiquitous protein involved in cell…”
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Left ventricular hypertrophy and its regression in essential arterial hypertension
Published in American journal of hypertension (01-10-2004)“…The mitral annulus velocities of Doppler transmitral flow and pulsed-wave tissue Doppler imaging (TDI) were sampled by echocardiography for the assessment of…”
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Low-Grade Inflammation and Microalbuminuria in Hypertension
Published in Arteriosclerosis, thrombosis, and vascular biology (01-12-2004)“…BACKGROUND—Albuminuria and C-reactive protein (CRP), a marker of systemic low-grade inflammation, are frequently elevated in essential hypertension and predict…”
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