Search Results - "Dell'elba, G."

Roflumilast inhibits leukocyte–platelet interactions and prevents the prothrombotic functions of polymorphonuclear leukocytes and monocytes by Totani, L., Amore, C., Di Santo, A., Dell'Elba, G., Piccoli, A., Martelli, N., Tenor, H., Beume, R., Evangelista, V.

“…Essentials Thrombosis is a major comorbidity in patients with chronic obstructive pulmonary disease (COPD). Roflumilast is a selective phosphodiesterase type‐4…”
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Fish intake is associated with lower cardiovascular risk in a Mediterranean population: Prospective results from the Moli-sani study by Bonaccio, M., Ruggiero, E., Di Castelnuovo, A., Costanzo, S., Persichillo, M., De Curtis, A., Cerletti, C., Donati, M.B., de Gaetano, G., Iacoviello, L., Iacoviello, L., Donati, M.B., de Gaetano, G., Vermylen, J., De Paula Carrasco, I., Giampaoli, S., Spagnuolo, A., Assanelli, D., Centritto, V., Spagnuolo, P., Staniscia, D., Zito, F., Bonanni, A., Cerletti, C., De Curtis, A., Di Castelnuovo, A., Lorenzet, R., Mascioli, A., Olivieri, M., Rotilio, D., Bonaccio, M., Costanzo, S., Gianfagna, F., Giacci, M., Padulo, A., Petraroia, D., Magnacca, S., Marracino, F., Spinelli, M., Silvestri, C., dell’Elba, G., Grippi, C., De Lucia, F., Vohnout, B., Persichillo, M., Verna, A., Di Lillo, M., Di Stefano, I., Pampuch, A., Pannichella, A., Vizzarri, A.R., Arcari, A., Barbato, D., Bracone, F., Di Giorgio, C., Panebianco, S., Chiovitti, A., Caccamo, S., Caruso, V., Rago, L., Cugino, D., Ferri, A., Castaldi, C., Mignogna, M., Guszcz, T., di Giuseppe, R., Barisciano, P., Buonaccorsi, L., Centritto, F., Cutrone, A., Fanelli, F., Santimone, I., Sciarretta, A., Sorella, I., Plescia, E., Molinaro, A., Cavone, C., Galuppo, G., D'Angelo, D., Ramacciato, R.

“…Fish consumption reportedly reduces the risk of heart disease, but the evidence of cardiovascular advantages associated with fish intake within Mediterranean…”
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Glycogen synthase kinase‐3 negatively regulates tissue factor expression in monocytes interacting with activated platelets by DI SANTO, A., AMORE, C., DELL'ELBA, G., MANARINI, S., EVANGELISTA, V.

“…Background: At the site of vascular injury, monocytes (MN) interacting with activated platelets (PLT) synthesize tissue factor (TF) and promote thrombus…”
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TxA2‐mediated myocardial ischemia as a consequence of an acute lung inflammatory reaction in the rabbit by Evangelista, V., Dell'elba, G., Celardo, A., Manarini, S., Cerletti, C.

“…Epidemiological studies link acute infection of the respiratory tract to a transient increased risk of acute myocardial infarction. The underlying mechanisms…”
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Polymorphonuclear leukocyte-platelet interaction: role of P-selectin in thromboxane B2 and leukotriene C4 cooperative synthesis by Maugeri, N, Evangelista, V, Celardo, A, Dell'Elba, G, Martelli, N, Piccardoni, P, de Gaetano, G, Cerletti, C

“…In PMN/platelet suspensions stimulated by fMLP giant mixed aggregates are formed and TxB2 and LTC4 are synthesized as the result of the cooperation in the…”
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Persistent platelet activation in patients with type 2 diabetes treated with low doses of aspirin by EVANGELISTA, V., DE BERARDIS, G., TOTANI, L., AVANZINI, F., GIORDA, C. B., BRERO, L., LEVANTESI, G., MARELLI, G., PUPILLO, M., IACUITTI, G., POZZOLI, G., DI SUMMA, P., NADA, E., DE SIMONE, G., DELL’ELBA, G., AMORE, C., MANARINI, S., PECCE, R., MAIONE, A., TOGNONI, G., NICOLUCCI, A.

“…Background:  The percentage of diabetic patients who do not benefit from the protective effect of aspirin is larger than in other populations at cardiovascular…”
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Transcellular Metabolism of Arachidonic Acid: Increased Platelet Thromboxane Generation in the Presence of Activated Polymorphonuclear Leukocytes by Maugeri, Norma, Evangelista, Virgilio, Piccardoni, Paola, Dell’Elba, Giuseppe, Celardo, Antonio, Gaetano, Giovanni de, Cerletti, Chiara

“…Human polymorphonuclear leukocytes (PMN) activated by n-formyl-methionyl-leucyl-phenylalanine (fMLP), in the presence of cytochalasin B, are able to induce…”
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Clopidogrel inhibits platelet-leukocyte adhesion and platelet-dependent leukocyte activation by Evangelista, Virgilio, Manarini, Stefano, Dell'Elba, Giuseppe, Martelli, Nicola, Napoleone, Emanuela, Di Santo, Angelomaria, Lorenzet, Pierre Savi Roberto

“…Clopidogrel is considered to be an important therapeutic advance in anti-platelet therapy. We investigated whether inhibition by clopidogrel results in a…”
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Bioavailability of oral isbufylline in rabbits by CELARDO, A, DELL'ELBA, G, BONATI, M

“…The bioavailability of isbufylline was assessed in male rabbits given 12 mg/kg i.v. (intravenous) or per os (oral) according to a randomized design. The…”
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Pharmacokinetic and pharmacodynamic differences between two low dosages of aspirin may affect therapeutic outcomes by CERLETTI, Chiara, DELL'ELBA, Giuseppe, MANARINI, Stefano, PECCE, Romina, DI CASTELNUOVO, Augusto, SCORPIGLIONE, Nicola, FELIZIANI, Vincenzo, DE GAETANO, Giovanni

“…Meta-analyses of the prevention of major vascular events by aspirin suggest therapeutic equivalence of all dosages. However, the optimal dosage still remains…”
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GLYCOGEN SYNTHASE KINASE-3 NEGATIVELY REGULATES TISSUE FACTOR EXPRESSION IN MONOCYTES INTERACTING WITH ACTIVATED PLATELETS by Di Santo, A., Amore, C., Dell'Elba, G., Manarini, S., Evangelista, V.

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Licofelone, a dual lipoxygenase–cyclooxygenase inhibitor, downregulates polymorphonuclear leukocyte and platelet function by Rotondo, Serenella, Dell'Elba, Giuseppe, Krauze-Brzósko, Katarzyna, Manarini, Stefano, Martelli, Nicola, Pecce, Romina, Evangelista, Virgilio, Cerletti, Chiara

“…Polymorphonuclear leukocytes are strongly implicated in the pathogenesis of inflammatory disease. Polymorphonuclear leukocyte recruitment at sites of…”
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Prasugrel inhibits platelet-leukocyte interaction and reduces inflammatory markers in a model of endotoxic shock in the mouse by Totani, Licia, Dell'Elba, Giuseppe, Martelli, Nicola, Di Santo, Angelomaria, Piccoli, Antonio, Amore, Concetta, Evangelista, Virgilio

“…Prasugrel, through its active metabolite, reduces atherothrombosis and its clinical manifestations by inhibiting platelet activation and aggregation. Platelets…”
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Simultaneous determination of isbufylline and its major metabolites in rabbit blood and urine by reversed-phase high-performance liquid chromatography by Celardo, A, Dell'Elba, G, Frassanito, R, Benfenati, E, Bonati, M

“…A sensitive high-performance liquid chromatographic assay for isbufylline and its major metabolites in rabbit blood and urine is described. After extraction,…”
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Platelet contribution to leukotriene production in inflammation: in vivo evidence in the rabbit by Evangelista, V, Celardo, A, Dell'Elba, G, Manarini, S, Mironov, A, de Gaetano, G, Cerletti, C

“…The contribution of platelets to arachidonic acid transcellular metabolism may represent an important pathway of leukotriene (LT) production. The aim of this…”
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N-omega-carbethoxypentyl-4-quinolones: a new class of leukotriene biosynthesis inhibitors by Desideri, N, Sestili, I, Stein, M L, Manarini, S, Dell'Elba, G, Cerletti, C

“…6-[(4-Quinolinyl)oxy]hexanoic acids and the corresponding esters were designed and synthesized as inhibitors of the production of arachidonic acid metabolites…”
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Kinetic evaluation of endogenous leukotriene B4 and E4 acute activation of inflammatory cells in the rabbit by Celardo, A, Dell'Elba, G, Manarini, S, Evangelista, V, de Gaetano, G, Cerletti, C

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Transcellular metabolism of arachidonic acid: increased platelet thromboxane generation in the presence of activated polymorphonuclear leukocytes by Maugeri, N, Evangelista, V, Piccardoni, P, Dell'Elba, G, Celardo, A, de Gaetano, G, Cerletti, C

“…Human polymorphonuclear leukocytes (PMN) activated by n-formyl- methionyl-leucyl-phenylalanine (fMLP), in the presence of cytochalasin B, are able to induce…”
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Kinetics of endogenous leukotriene B sub(4) and E sub(4) production following injection of the chemotactic peptide FMLP in the rabbit by Celardo, A, Dell'Elba, G, Manarini, S, Evangelista, V, de Gaetano, G, Cerletti, C

“…The kinetic profiles of leukotriene B sub(4) (LTB sub(4)) and E sub(4) (LTE sub(4)) after intravenous administration (30 nmol/kg) of the inflammatory peptide…”
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Simultaneous determination of leukotrienes B4 and E4 in whole blood and of leukotriene E4 in urine of rabbit by reversed-phase high-performance liquid chromatography by Celardo, A, Dell'Elba, G, Eltantawy, Z M, Evangelista, V, Cerletti, C

“…Sulfidopeptide leukotrienes E4 (LTE4) and B4 (LTB4) were simultaneously extracted from rabbit whole blood with acetonitrile. LTC4 and LTD4 were converted to…”
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