Search Results - "Dell'Italia, Louis J."

Novel Paradigms of Salt and Hypertension by Feng, Wenguang, Dell'Italia, Louis J, Sanders, Paul W

“…Salt resistance/sensitivity refers specifically to the effect of dietary sodium chloride (salt) intake on BP. Increased dietary salt intake promotes an early…”
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Activation of AKT by O-Linked N-Acetylglucosamine Induces Vascular Calcification in Diabetes Mellitus by Heath, Jack M, Sun, Yong, Yuan, Kaiyu, Bradley, Wayne E, Litovsky, Silvio, Dell’Italia, Louis J, Chatham, John C, Wu, Hui, Chen, Yabing

“…RATIONALE:Vascular calcification is a serious cardiovascular complication that contributes to the increased morbidity and mortality of patients with diabetes…”
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Hemoglobin and Iron Cellular Delivery During Cardiopulmonary Bypass by Dell’Italia, Louis J., Eudailey, Kyle, Pat, Betty, Lewis, Clifton, Patel, Rakesh, Davies, James E.

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Maintaining Myocardial Glucose Utilization in Diabetic Cardiomyopathy Accelerates Mitochondrial Dysfunction by Wende, Adam R, Schell, John C, Ha, Chae-Myeong, Pepin, Mark E, Khalimonchuk, Oleh, Schwertz, Hansjörg, Pereira, Renata O, Brahma, Manoja K, Tuinei, Joseph, Contreras-Ferrat, Ariel, Wang, Li, Andrizzi, Chase A, Olsen, Curtis D, Bradley, Wayne E, Dell'Italia, Louis J, Dillmann, Wolfgang H, Litwin, Sheldon E, Abel, E Dale

“…Cardiac glucose uptake and oxidation are reduced in diabetes despite hyperglycemia. Mitochondrial dysfunction contributes to heart failure in diabetes. It is…”
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Anatomy and Physiology of the Right Ventricle by Dell’Italia, Louis J., MD

“…Under normal baseline conditions the unique anatomy, myocardial ultrastructure, and coronary physiology of the right ventricle (RV) reflect a high-volume…”
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Cardiac O-GlcNAcylation blunts autophagic signaling in the diabetic heart by Marsh, Susan A., Powell, Pamela C., Dell'Italia, Louis J., Chatham, John C.

“…Increased O-linked attachment of β-N-acetylglucosamine (O-GlcNAc) to proteins has been implicated in the adverse effects of diabetes on the heart, although…”
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Desmin loss and mitochondrial damage precede left ventricular systolic failure in volume overload heart failure by Guichard, Jason L, Rogowski, Michael, Agnetti, Giulio, Fu, Lianwu, Powell, Pamela, Wei, Chih-Chang, Collawn, James, Dell'Italia, Louis J

“…Heart failure due to chronic volume overload (VO) in rats and humans is characterized by disorganization of the cardiomyocyte desmin/mitochondrial network…”
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Effects of Right Ventricular Ejection Fraction on Outcomes in Chronic Systolic Heart Failure by MEYER, Philippe, FILIPPATOS, Gerasimos S, AHMED, Ali, AHMED, Mustafa I, ISKANDRIAN, Ami E, BITTNER, Vera, PERRY, Gilbert J, WHITE, Michel, ABAN, Inmaculada B, MUJIB, Marjan, DELL'ITALIA, Louis J

“…Studies of the effect of right ventricular ejection fraction (RVEF) on outcomes in heart failure (HF) are limited by small sample size and short follow-up. We…”
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Increased Inflammation in Pericardial Fluid Persists 48 Hours After Cardiac Surgery by Butts, Brittany, Goeddel, Lee A, George, David J, Steele, Chad, Davies, James E, Wei, Chih-Chang, Varagic, Jasmina, George, James F, Ferrario, Carlos M, Melby, Spencer J, Dell’Italia, Louis J

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Elevated cardiac hemoglobin expression is associated with a pro-oxidative and inflammatory environment in primary mitral regurgitation by Manzoor, Shajer, Kane, Mariame Selma, Grenett, Maximiliano, Oh, Joo-Yeun, Pat, Betty, Lewis, Clifton, Davies, James E., Steele, Chad, Patel, Rakesh P., Dell’Italia, Louis J.

“…Primary mitral regurgitation (PMR) is associated with oxidative and inflammatory myocardial damage. We reported greater exosome hemoglobin (Hb) in pericardial…”
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Plasma xanthine oxidase activity is related to increased sodium and left ventricular hypertrophy in resistant hypertension by Butts, Brittany, Calhoun, David A., Denney, Thomas S., Lloyd, Steven G., Gupta, Himanshu, Gaddam, Krishna K., Aban, Inmaculada, Oparil, Suzanne, Sanders, Paul W., Patel, Rakesh, Collawn, James F., Dell’Italia, Louis J.

“…The extra-renal effects of aldosterone on left ventricular (LV) structure and function are exacerbated by increased dietary sodium in persons with…”
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Red blood cell exosome hemoglobin content increases after cardiopulmonary bypass and mediates acute kidney injury in an animal model by Pat, Betty, Oh, Joo-Yeun, Masjoan Juncos, Juan Xavier, Powell, Pamela C., Collawn, James F., Patel, Rakesh P., Dell’Italia, Louis J., Middleton, David, Andrikopoulou, Efstathia, Gutierrez, Orlando, Bradley, Wayne E., Mrug, Michael, Aban, Inmaculada, Richman, Joshua, Lewis, Clifton, Davies, James E.

“…Hemolysis, characterized by formation of free hemoglobin (Hb), occurs in patients undergoing cardiopulmonary bypass (CPB). However, there is no study of the…”
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Early exposure to hyperoxia or hypoxia adversely impacts cardiopulmonary development by Ramani, Manimaran, Bradley, Wayne E, Dell'Italia, Louis J, Ambalavanan, Namasivayam

“…Preterm infants are at high risk for long-term abnormalities in cardiopulmonary function. Our objectives were to determine the long-term effects of hypoxia or…”
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Plasma Exosome Hemoglobin Released During Surgery Is Associated With Cardiac Injury in Animal Model by Eudailey, Kyle W., Pat, Betty, Oh, Joo-Yeun, Powell, Pamela C., Collawn, James F., Mobley, James A., Gaggar, Amit, Lewis, Clifton T., Davies, James E., Patel, Rakesh, Dell’Italia, Louis J.

“…Patients with valvular heart disease require cardiopulmonary bypass and cardiac arrest. Here, we test the hypothesis that exosomal hemoglobin formed during…”
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Intracrine angiotensin II functions originate from noncanonical pathways in the human heart by Ferrario, Carlos M, Ahmad, Sarfaraz, Varagic, Jasmina, Cheng, Che Ping, Groban, Leanne, Wang, Hao, Collawn, James F, Dell Italia, Louis J

“…Although it is well-known that excess renin angiotensin system (RAS) activity contributes to the pathophysiology of cardiac and vascular disease, tissue-based…”
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Mitochondrial genetic background modulates bioenergetics and susceptibility to acute cardiac volume overload by Fetterman, Jessica L, Zelickson, Blake R, Johnson, Larry W, Moellering, Douglas R, Westbrook, David G, Pompilius, Melissa, Sammy, Melissa J, Johnson, Michelle, Dunham-Snary, Kimberly J, Cao, Xuemei, Bradley, Wayne E, Zhang, Jinju, Wei, Chih-Chang, Chacko, Balu, Schurr, Theodore G, Kesterson, Robert A, Dell'italia, Louis J, Darley-Usmar, Victor M, Welch, Danny R, Ballinger, Scott W

“…Dysfunctional bioenergetics has emerged as a key feature in many chronic pathologies such as diabetes and cardiovascular disease. This has led to the…”
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Refractory Hypertension: Definition, Prevalence, and Patient Characteristics by Acelajado, Maria Czarina, Pisoni, Roberto, Dudenbostel, Tanja, Dell’Italia, Louis J., Cartmill, Falynn, Zhang, Bin, Cofield, Stacey S., Oparil, Suzanne, Calhoun, David A.

“…J Clin Hypertens (Greenwich). Among patients with resistant hypertension (RHTN), there are those whose blood pressure (BP) remains uncontrolled in spite of…”
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Bromine inhalation mimics ischemia-reperfusion cardiomyocyte injury and calpain activation in rats by Ahmad, Shama, Masjoan Juncos, Juan Xavier, Ahmad, Aftab, Zaky, Ahmed, Wei, Chih-Chang, Bradley, Wayne E, Zafar, Iram, Powell, Pamela, Mariappan, Nithya, Vetal, Nilam, Louch, William E, Ford, David A, Doran, Stephen F, Matalon, Sadis, Dell'Italia, Louis J

“…Halogens are widely used, highly toxic chemicals that pose a potential threat to humans because of their abundance. Halogens such as bromine (Br ) cause severe…”
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Spironolactone improves left atrial function and atrioventricular coupling in patients with resistant hypertension by Girard, Andrew A., Denney, Thomas S., Gupta, Himanshu, Dell’Italia, Louis J., Calhoun, David A., Oparil, Suzanne, Sharifov, Oleg F., Lloyd, Steven G.

“…To determine the blood pressure independent effects of spironolactone on left atrial (LA) size and function in patients with resistant hypertension (RHTN)…”
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Rapid Reversal of Left Ventricular Hypertrophy and Intracardiac Volume Overload in Patients With Resistant Hypertension and Hyperaldosteronism: A Prospective Clinical Study by Gaddam, Krishna, Corros, Cecilia, Pimenta, Eduardo, Ahmed, Mustafa, Denney, Thomas, Aban, Inmaculada, Inusah, Seidu, Gupta, Himanshu, Lloyd, Steven G, Oparil, Suzanne, Husain, Ahsan, DellʼItalia, Louis J, Calhoun, David A

“…We have shown previously that patients with resistant hypertension and hyperaldosteronism have increased brain natriuretic peptide suggestive of increased…”
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