Search Results - "Delk, Nikkí A"
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CML24, Regulated in Expression by Diverse Stimuli, Encodes a Potential Ca²⁺ Sensor That Functions in Responses to Abscisic Acid, Daylength, and Ion Stress
Published in Plant physiology (Bethesda) (01-09-2005)“…Changes in intracellular calcium (Ca²⁺) levels serve to signal responses to diverse stimuli. Ca²⁺ signals are likely perceived through proteins that bind Ca²⁺,…”
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2
A microphysiological system reveals neutrophil contact-dependent attenuation of pancreatic tumor progression by CXCR2 inhibition-based immunotherapy
Published in Scientific reports (19-06-2024)“…Cancer cells recruit neutrophils from the bloodstream into the tumor tissue, where these immune cells promote the progression of numerous solid tumors. Studies…”
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3
Interleukin-1 and Nuclear Factor Kappa B Signaling Promote Breast Cancer Progression and Treatment Resistance
Published in Cells (Basel, Switzerland) (18-05-2022)“…While meant for wound healing and immunity in response to injury and infection, inflammatory signaling is usurped by cancerous tumors to promote disease…”
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4
Chronic IL-1 exposure drives LNCaP cells to evolve androgen and AR independence
Published in PloS one (16-12-2020)“…Chronic inflammation promotes prostate cancer (PCa) initiation and progression. We previously reported that acute intereluekin-1 (IL-1) exposure represses…”
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5
Calmodulin‐related CML24 interacts with ATG4b and affects autophagy progression in Arabidopsis
Published in The Plant journal : for cell and molecular biology (2013)“…Plants encounter environmental stress challenges that are distinct from those of other eukaryotes because of their relative immobility. Therefore, plants may…”
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6
Interleukin-6: A bone marrow stromal cell paracrine signal that induces neuroendocrine differentiation and modulates autophagy in bone metastatic PCa cells
Published in Autophagy (01-04-2012)“…Autophagy reallocates nutrients and clears normal cells of damaged proteins and organelles. In the context of metastatic disease, invading cancer cells hijack…”
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7
Neuronal Trans-Differentiation in Prostate Cancer Cells
Published in The Prostate (01-10-2016)“…BACKGROUND Neuroendocrine (NE) differentiation in prostate cancer (PCa) is an aggressive phenotype associated with therapy resistance. The complete phenotype…”
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8
IL-1-conferred gene expression pattern in ERα + BCa and AR + PCa cells is intrinsic to ERα - BCa and AR - PCa cells and promotes cell survival
Published in BMC cancer (20-01-2020)“…Breast (BCa) and prostate (PCa) cancers are hormone receptor (HR)-driven cancers. Thus, BCa and PCa patients are given therapies that reduce hormone levels or…”
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p62/SQSTM1 is required for cell survival of apoptosis-resistant bone metastatic prostate cancer cell lines
Published in The Prostate (01-02-2014)“…BACKGROUND Bone marrow stromal cell (BMSC) paracrine factor(s) can induce apoptosis in bone metastatic prostate cancer (PCa) cell lines. However, the PCa cells…”
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10
Arabidopsis Potential Calcium Sensors Regulate Nitric Oxide Levels and the Transition to Flowering
Published in Plant signaling & behavior (01-11-2007)“…In plants, flowering is a critical developmental transition orchestrated by four regulatory pathways. Distinct alleles encoding mutant forms of the Arabidopsis…”
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11
NF-κB signaling promotes castration-resistant prostate cancer initiation and progression
Published in Pharmacology & therapeutics (Oxford) (01-07-2020)“…Prostate Cancer (PCa) is the second leading cause of cancer-related death in men. Adenocarcinoma of the prostate is primarily composed of Androgen…”
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12
The in vivo performance of plasmonic nanobubbles as cell theranostic agents in zebrafish hosting prostate cancer xenografts
Published in Biomaterials (01-10-2010)“…Abstract Cell theranostics is a new approach that unites diagnosis, therapy and confirmation (guidance) of the results of therapy in one single process at cell…”
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13
RELA is sufficient to mediate interleukin‐1 repression of androgen receptor expression and activity in an LNCaP disease progression model
Published in The Prostate (01-02-2020)“…Background The androgen receptor (AR) nuclear transcription factor is a therapeutic target for prostate cancer (PCa). Unfortunately, patients can develop…”
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14
Identification of an IL‐1‐induced gene expression pattern in AR+ PCa cells that mimics the molecular phenotype of AR− PCa cells
Published in The Prostate (01-06-2018)“…Background In immunosurveillance, bone‐derived immune cells infiltrate the tumor and secrete inflammatory cytokines to destroy cancer cells. However, cancer…”
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15
Altered Subcellular Localization of Tumor-Specific Cyclin E Isoforms Affects Cyclin-Dependent Kinase 2 Complex Formation and Proteasomal Regulation
Published in Cancer research (Chicago, Ill.) (01-04-2009)“…In tumors, alternative translation and posttranslational proteolytic cleavage of full-length cyclin E (EL) produces tumorigenic low molecular weight cyclin E…”
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IL-1β Induces p62/SQSTM1 and Represses Androgen Receptor Expression in Prostate Cancer Cells
Published in Journal of cellular biochemistry (01-12-2014)“…ABSTRACT Chronic inflammation is associated with advanced prostate cancer (PCa), although the mechanisms governing inflammation‐mediated PCa progression are…”
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17
Calmodulin‐related CML 24 interacts with ATG 4b and affects autophagy progression in A rabidopsis
Published in The Plant journal : for cell and molecular biology (01-01-2013)“…Plants encounter environmental stress challenges that are distinct from those of other eukaryotes because of their relative immobility. Therefore, plants may…”
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Journal Article -
18
CML24, Regulated in Expression by Diverse Stimuli, Encodes a Potential Ca^sup 2+^ Sensor That Functions in Responses to Abscisic Acid, Daylength, and Ion Stress1
Published in Plant physiology (Bethesda) (01-09-2005)“…Changes in intracellular calcium (Ca(2+)) levels serve to signal responses to diverse stimuli. Ca(2+) signals are likely perceived through proteins that bind…”
Get full text
Journal Article -
19
CML24, Regulated in Expression by Diverse Stimuli, Encodes a Potential Ca2+ Sensor That Functions in Responses to Abscisic Acid, Daylength, and Ion Stress1
Published in Plant physiology (Bethesda) (01-09-2005)“…Changes in intracellular calcium (Ca 2+ ) levels serve to signal responses to diverse stimuli. Ca 2+ signals are likely perceived through proteins that bind Ca…”
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Journal Article -
20
Abstract 287: Novel p62 interaction suggests novel role in glutamate metabolism
Published in Cancer research (Chicago, Ill.) (04-04-2023)“…Prostate cancer (PCa) is the second most common cause of cancer-related death among American men. Androgen Receptor (AR) transcriptional activity is required…”
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