Search Results - "Delitto, Andrea E."

Relevance of Caspase-1 and Nlrp3 Inflammasome on Inflammatory Bone Resorption in A Murine Model of Periodontitis by Rocha, Fernanda R G., Delitto, Andrea E., de Souza, Joao A. Chaves, González-Maldonado, Laura A., Wallet, Shannon M., Rossa Junior, Carlos

“…This study investigates the role of NLRP3 inflammasome and its main effector Caspase-1 in inflammation and alveolar bone resorption associated with…”
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Tumour‐derived leukaemia inhibitory factor is a major driver of cancer cachexia and morbidity in C26 tumour‐bearing mice by Kandarian, Susan C., Nosacka, Rachel L., Delitto, Andrea E., Judge, Andrew R., Judge, Sarah M., Ganey, John D., Moreira, Jesse D., Jackman, Robert W.

“…Background Cancer cachexia is a metabolic wasting syndrome that is strongly associated with a poor prognosis. The initiating factors causing fat and muscle…”
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Distinct cachexia profiles in response to human pancreatic tumours in mouse limb and respiratory muscle by Nosacka, Rachel L., Delitto, Andrea E., Delitto, Dan, Patel, Rohan, Judge, Sarah M., Trevino, Jose G., Judge, Andrew R.

“…Background Cancer cachexia is a life‐threatening metabolic syndrome that causes significant loss of skeletal muscle mass and significantly increases mortality…”
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Human Pancreatic Cancer Cells Induce a MyD88-Dependent Stromal Response to Promote a Tumor-Tolerant Immune Microenvironment by Delitto, Daniel, Delitto, Andrea E, DiVita, Bayli B, Pham, Kien, Han, Song, Hartlage, Emily R, Newby, Brittney N, Gerber, Michael H, Behrns, Kevin E, Moldawer, Lyle L, Thomas, Ryan M, George, Jr, Thomas J, Brusko, Todd M, Mathews, Clayton E, Liu, Chen, Trevino, Jose G, Hughes, Steven J, Wallet, Shannon M

“…Cancer cells exert mastery over the local tumor-associated stroma (TAS) to configure protective immunity within the tumor microenvironment. The…”
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Local and Systemic Cytokine Profiling for Pancreatic Ductal Adenocarcinoma to Study Cancer Cachexia in an Era of Precision Medicine by Gerber, Michael H, Underwood, Patrick W, Judge, Sarah M, Delitto, Daniel, Delitto, Andrea E, Nosacka, Rachel L, DiVita, Bayli B, Thomas, Ryan M, Permuth, Jennifer B, Hughes, Steven J, Wallet, Shannon M, Judge, Andrew R, Trevino, Jose G

“…Cancer cachexia is a debilitating condition seen frequently in patients with pancreatic ductal adenocarcinoma (PDAC). The underlying mechanisms driving cancer…”
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Human pancreatic cancer xenografts recapitulate key aspects of cancer cachexia by Delitto, Daniel, Judge, Sarah M, Delitto, Andrea E, Nosacka, Rachel L, Rocha, Fernanda G, DiVita, Bayli B, Gerber, Michael H, George, Jr, Thomas J, Behrns, Kevin E, Hughes, Steven J, Wallet, Shannon M, Judge, Andrew R, Trevino, Jose G

“…Cancer cachexia represents a debilitating syndrome that diminishes quality of life and augments the toxicities of conventional treatments. Cancer cachexia is…”
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Multiomic analysis reveals conservation of cancer-associated fibroblast phenotypes across species and tissue of origin by Foster, Deshka S., Januszyk, Michael, Delitto, Daniel, Yost, Kathryn E., Griffin, Michelle, Guo, Jason, Guardino, Nicholas, Delitto, Andrea E., Chinta, Malini, Burcham, Austin R., Nguyen, Alan T., Bauer-Rowe, Khristian E., Titan, Ashley L., Salhotra, Ankit, Jones, R. Ellen, da Silva, Oscar, Lindsay, Hunter G., Berry, Charlotte E., Chen, Kellen, Henn, Dominic, Mascharak, Shamik, Talbott, Heather E., Kim, Alexia, Nosrati, Fatemeh, Sivaraj, Dharshan, Ransom, R. Chase, Matthews, Michael, Khan, Anum, Wagh, Dhananjay, Coller, John, Gurtner, Geoffrey C., Wan, Derrick C., Wapnir, Irene L., Chang, Howard Y., Norton, Jeffrey A., Longaker, Michael T.

“…Cancer-associated fibroblasts (CAFs) are integral to the solid tumor microenvironment. CAFs were once thought to be a relatively uniform population of…”
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IL-8 Released from Human Pancreatic Cancer and Tumor-Associated Stromal Cells Signals through a CXCR2-ERK1/2 Axis to Induce Muscle Atrophy by Callaway, Chandler S, Delitto, Andrea E, Patel, Rohan, Nosacka, Rachel L, D'Lugos, Andrew C, Delitto, Daniel, Deyhle, Michael R, Trevino, Jose G, Judge, Sarah M, Judge, Andrew R

“…Tumor-derived cytokines are known to drive the catabolism of host tissues, including skeletal muscle. However, our understanding of the specific cytokines that…”
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NLRC4 inflammasome has a protective role on inflammatory bone resorption in a murine model of periodontal disease by Rocha, Fernanda R.G., Delitto, Andrea E., de Souza, Joao A Chaves, Maldonado, Laura A.G., Wallet, Shannon M., Rossa, Carlos

“…There is virtually no information on the role of NLRC4 inflammasome on bone resorption and inflammation associated with periodontitis. Bacterial-associated…”
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MyD88-mediated innate sensing by oral epithelial cells controls periodontal inflammation by Delitto, Andrea E., Rocha, Fernanda, Decker, Ann M., Amador, Byron, Sorenson, Heather L., Wallet, Shannon M.

“…•Loss of oral epithelial cell MyD88 expression results in exacerbated induced bone loss.•Loss of oral epithelial cell MyD88 expression results in induced…”
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