Search Results - "Delisser, Vern M"

Synthesis of A83586C Analogs with Potent Anticancer and β-Catenin/ TCF4/Osteopontin Inhibitory Effects and Insights Into How A83586C Modulates E2Fs and pRb by Hale, Karl J, Manaviazar, Soraya, Lazarides, Linos, George, Jonathan, Walters, Marcus A, Cai, Jiaqiang, Delisser, Vern M, Bhatia, Gurpreet S, Peak, S. Andrew, Dalby, Stephen M, Lefranc, Amandine, Chen, Ying-Nan P, Wood, Alexander W, Crowe, Paul, Erwin, Pauline, El-Tanani, Mohamed

“…The synthesis of three potent new antitumor agents is described: the A83586C−citropeptin hybrid (1), the A83586C−GE3 hybrid (2), and l-Pro-A83586C (3)…”
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Stereoselective synthesis of a functionalised bicyclic core of Neocarzinostatin and Kedarcidin Chromophores by Caddick, Stephen, Delisser, Vern M.

“…The stereoselective synthesis of a bicyclic ring system related to Neocarzinostatin and Kedarcidin Chromophores is described; key steps involve stereoselective…”
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Asymmetric synthesis of the C(1)C(47) backbone of antitumour antibiotic A83586C by Hale, Karl J, Cai, Jiaqiang, Delisser, Vern M

“…Protected pentapeptide 9 has been converted to hexapeptide 3 and this chemoselectively coupled to activated ester 2 to give 1 after glycal hydration during SiO…”
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Asymmetric dihydroxylation of homoallylic enynols by Caddick, Stephen, Shanmugathasan, Sakthitharan, Brasseur, Denis, Delisser, Vern M

“…The presence of the p-methoxyphenyl protecting group enables the asymmetric dihydroxylation of homoallylic enynols to be carried out in good yield and with…”
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Synthesis of a dihydroxylated dienediyne analogue related to neocarzinostatin chromophore by Caddick, Stephen, Khan, Safraz, Smith, Nichola J., Barr, Douglas M., Delisser, Vern M.

“…A 12-step synthesis of a dihydroxylated dienediyne analogue related to Neocarzinostatin Chromophore is reported. Graphic…”
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