Search Results - "Delinois, Louis J"
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Thiol-maleimide poly(ethylene glycol) crosslinking of L-asparaginase subunits at recombinant cysteine residues introduced by mutagenesis
Published in PloS one (27-07-2018)“…L-Asparaginase is an enzyme successfully being used in the treatment of acute lymphoblastic leukemia, acute myeloid leukemia, and non-Hodgkin's lymphoma…”
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Cytochrome c: Using Biological Insight toward Engineering an Optimized Anticancer Biodrug
Published in Inorganics (01-11-2021)“…The heme protein cytochrome c (Cyt c) plays pivotal roles in cellular life and death processes. In the respiratory chain of mitochondria, it serves as an…”
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Oxidative Stress- and Autophagy-Inducing Effects of PSI-LHCI from Botryococcus braunii in Breast Cancer Cells
Published in Biotech (Basel) (30-03-2022)“…( ) is a green microalga primarily found in freshwater, reservoirs, and ponds. Photosynthetic pigments from algae have shown many bioactive molecules with…”
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Poly(ADP-Ribose) Polymerase-1 Regulates Pyroptosis Independent Function of NLRP3 Inflammasome in Neutrophil Extracellular Trap Formation
Published in ImmunoHorizons (01-08-2024)“…Neutrophil extracellular traps (NETs) function to control infectious agents as well as to propagate inflammatory response in a variety of disease conditions…”
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A Cytochrome c‐Chlorotoxin Hybrid Protein as a Possible Antiglioma Drug
Published in ChemMedChem (18-11-2020)“…Malignant gliomas are the most lethal form of primary brain tumors. Despite advances in cancer therapy, the prognosis of glioma patients has remained poor…”
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Key genes and drug delivery systems to improve the efficiency of chemotherapy
Published in Cancer drug resistance (01-01-2021)“…Cancer cells can develop resistance to anticancer drugs, thereby becoming tolerant to treatment through different mechanisms. The biological mechanisms leading…”
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Covalent Crosslinking of L‐Asparaginase II Subunits by Site‐Specific PEGylation
Published in The FASEB journal (01-04-2017)“…L‐Asparaginase II is a homo‐tetramer enzyme that catalyzes the hydrolysis of asparagine, which is an essential amino acid for leukemia cells. Used as a drug,…”
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