Search Results - "Delgado, Norma L."
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Helminth‐derived molecules inhibit colitis‐associated colon cancer development through NF‐κB and STAT3 regulation
Published in International journal of cancer (01-12-2019)“…Inflammation is currently considered a hallmark of cancer and plays a decisive role in different stages of tumorigenesis, including initiation, promotion,…”
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STAT1 Is Required for Decreasing Accumulation of Granulocytic Cells via IL-17 during Initial Steps of Colitis-Associated Cancer
Published in International journal of molecular sciences (19-07-2021)“…Signal transducer and activator of transcription 1 (STAT1) acts as a tumor suppressor molecule in colitis-associated colorectal cancer (CAC), particularly…”
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Food‐grade titanium dioxide (E171) by solid or liquid matrix administration induces inflammation, germ cells sloughing in seminiferous tubules and blood‐testis barrier disruption in mice
Published in Journal of applied toxicology (01-11-2019)“…Food‐grade titanium dioxide labeled as E171 has been approved for human consumption by the Food and Drug Administration (USA) and by the European Union for…”
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Nrf2 protects the lung against inflammation induced by titanium dioxide nanoparticles: A positive regulator role of Nrf2 on cytokine release
Published in Environmental toxicology (01-07-2015)“…Titanium dioxide nanoparticles (TiO₂ NPs) have been classified as possibly carcinogenic to humans and they are an important nanomaterial widely used in…”
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Use of STAT6 Phosphorylation Inhibitor and Trimethylglycine as New Adjuvant Therapies for 5-Fluorouracil in Colitis-Associated Tumorigenesis
Published in International journal of molecular sciences (20-03-2020)“…Colorectal cancer (CRC) is one of the most widespread and deadly types of neoplasia around the world, where the inflammatory microenvironment has critical…”
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Combination of Metformin, Sodium Oxamate and Doxorubicin Induces Apoptosis and Autophagy in Colorectal Cancer Cells via Downregulation HIF-1α
Published in Frontiers in oncology (26-05-2021)“…Colorectal cancer (CRC) is the third leading cause of cancer-related death worldwide in both sexes. Current therapies include surgery, chemotherapy, and…”
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Lack of STAT6 Attenuates Inflammation and Drives Protection against Early Steps of Colitis-Associated Colon Cancer
Published in Cancer immunology research (01-05-2017)“…Colitis-associated colon cancer (CAC) is one of the most common malignant neoplasms and a leading cause of death. The immunologic factors associated with CAC…”
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The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer
Published in Nanomaterials (Basel, Switzerland) (01-04-2022)“…Titanium dioxide (TiO ) is present in many different food products as the food additive E171, which is currently scrutinized due to its potential adverse…”
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Reply to Kaminski, N.E.; Cohen, S.M. Comment on "Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12 , 1256"
Published in Nanomaterials (Basel, Switzerland) (05-05-2023)“…We appreciate the interest in our article describing transcriptome changes in a transgenic mouse model carrying an APC gene mutation and would like to reply to…”
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Role of Wasp and the small GTPases RhoA, RhoB, and Cdc42 during capacitation and acrosome reaction in spermatozoa of English guinea pigs
Published in Molecular reproduction and development (01-10-2016)“…SUMMARY Cytoskeleton remodeling is necessary for capacitation and the acrosome reaction in spermatozoa. F‐actin is located in the acrosome and equatorial…”
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Mannheimia haemolytica OmpP2-like is an amyloid-like protein, forms filaments, takes part in cell adhesion and is part of biofilms
Published in Antonie van Leeuwenhoek (01-12-2018)“…Mannheimia haemolytica causes respiratory disease in cattle. Amyloid proteins are a major component of biofilms; they aid in adhesion and confer resistance…”
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International landscape of limits and recommendations for occupational exposure to engineered nanomaterials
Published in Toxicology letters (01-04-2020)“…•Information required for nanomaterials registration is mainly based on tonnage.•Sub-nanometric nanomaterials and nanofibers could have different criteria for…”
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Correction: Bischoff et al. The Effects of the Food Additive Titanium Dioxide (E171) on Tumor Formation and Gene Expression in the Colon of a Transgenic Mouse Model for Colorectal Cancer. Nanomaterials 2022, 12, 1256
Published in Nanomaterials (Basel, Switzerland) (31-10-2023)“…In the published publication [...]…”
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Differences in cytotoxicity of lung epithelial cells exposed to titanium dioxide nanofibers and nanoparticles: Comparison of air-liquid interface and submerged cell cultures
Published in Toxicology in vitro (01-06-2020)“…Air Liquid Interface (ALI) system has emerged as a useful tool for toxicity evaluation of nanomaterials related to inhalation since the system mimics the…”
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Toxicity of engineered nanomaterials with different physicochemical properties and the role of protein corona on cellular uptake and intrinsic ROS production
Published in Toxicology (Amsterdam) (01-09-2020)“…[Display omitted] •TiO2 NFs have higher protein absorption than SiO2 NPs and ITO NPs.•Coating of TiO2 NFs, SiO2 NPs and ITO NPs does not change their intrinsic…”
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Irreversible disruption of the cytoskeleton as induced by non-cytotoxic exposure to titanium dioxide nanoparticles in lung epithelial cells
Published in Chemico-biological interactions (25-05-2020)“…Exposure to TiO2 NPs induces several cellular alterations after NPs uptake including disruption of cytoskeleton that is crucial for lung physiology but is not…”
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Differential response of immobile (pneumocytes) and mobile (monocytes) barriers against 2 types of metal oxide nanoparticles
Published in Chemico-biological interactions (25-09-2021)“…Inhaled nanoparticles (NPs) challenges mobile and immobile barriers in the respiratory tract, which can be represented by type II pneumocytes (immobile) and…”
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Mexican Colorectal Cancer Research Consortium (MEX-CCRC): Etiology, Diagnosis/Prognosis, and Innovative Therapies
Published in International journal of molecular sciences (20-01-2023)“…In 2013, recognizing that Colorectal Cancer (CRC) is the second leading cause of death by cancer worldwide and that it was a neglected disease increasing…”
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Deficiency in STAT1 Signaling Predisposes Gut Inflammation and Prompts Colorectal Cancer Development
Published in Cancers (19-09-2018)“…Signal transducer and activator of transcription 1 (STAT1) is part of the Janus kinase (JAK/STAT) signaling pathway that controls critical events in intestinal…”
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Influence of shape and dispersion media of titanium dioxide nanostructures on microvessel network and ossification
Published in Colloids and surfaces, B, Biointerfaces (01-02-2018)“…[Display omitted] •Hydrodynamic size and zeta potential were higher for all types of nanoparticles dispersed in saline solution.•All particles dispersed in…”
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