Search Results - "Delekate, Andrea"

Inhibition of Stat3‐mediated astrogliosis ameliorates pathology in an Alzheimer's disease model by Reichenbach, Nicole, Delekate, Andrea, Plescher, Monika, Schmitt, Franziska, Krauss, Sybille, Blank, Nelli, Halle, Annett, Petzold, Gabor C

“…Reactive astrogliosis is a hallmark of Alzheimer's disease (AD), but its role for disease initiation and progression has remained incompletely understood. We…”
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NLRP3 is activated in Alzheimer’s disease and contributes to pathology in APP/PS1 mice by Heneka, Michael T., Kummer, Markus P., Stutz, Andrea, Delekate, Andrea, Schwartz, Stephanie, Vieira-Saecker, Ana, Griep, Angelika, Axt, Daisy, Remus, Anita, Tzeng, Te-Chen, Gelpi, Ellen, Halle, Annett, Korte, Martin, Latz, Eicke, Golenbock, Douglas T.

“…Alzheimer’s-prone mice deficient in NLRP3 or caspase-1 fail to develop learning deficits and show reduced neuropathology. Inflammasome a target in Alzheimer's…”
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P2Y1 receptor blockade normalizes network dysfunction and cognition in an Alzheimer's disease model by Reichenbach, Nicole, Delekate, Andrea, Breithausen, Björn, Keppler, Kevin, Poll, Stefanie, Schulte, Theresa, Peter, Jan, Plescher, Monika, Hansen, Jan N, Blank, Nelli, Keller, Armin, Fuhrmann, Martin, Henneberger, Christian, Halle, Annett, Petzold, Gabor C

“…Astrocytic hyperactivity is an important contributor to neuronal-glial network dysfunction in Alzheimer's disease (AD). We have previously shown that astrocyte…”
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Astroglial NF-kB contributes to white matter damage and cognitive impairment in a mouse model of vascular dementia by Saggu, Raman, Schumacher, Toni, Gerich, Florian, Rakers, Cordula, Tai, Khalid, Delekate, Andrea, Petzold, Gabor C

“…Vascular cognitive impairment is the second most common form of dementia. The pathogenic pathways leading to vascular cognitive impairment remain unclear but…”
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NogoA restricts synaptic plasticity in the adult hippocampus on a fast time scale by Delekate, Andrea, Zagrebelsky, Marta, Kramer, Stella, Schwab, Martin E, Korte, Martin

“…Whereas the role of NogoA in limiting axonal fiber growth and regeneration following an injury of the mammalian central nervous system (CNS) is well known, its…”
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Sodium Fluctuations in Astroglia and Their Potential Impact on Astrocyte Function by Felix, Lisa, Delekate, Andrea, Petzold, Gabor C., Rose, Christine R.

“…Astrocytes are the main cell type responsible for the regulation of brain homeostasis, including the maintenance of ion gradients and neurotransmitter…”
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Local Resting Ca2+ Controls the Scale of Astroglial Ca2+ Signals by King, Claire M., Bohmbach, Kirsten, Minge, Daniel, Delekate, Andrea, Zheng, Kaiyu, Reynolds, James, Rakers, Cordula, Zeug, Andre, Petzold, Gabor C., Rusakov, Dmitri A., Henneberger, Christian

“…Astroglia regulate neurovascular coupling while engaging in signal exchange with neurons. The underlying cellular machinery is thought to rely on astrocytic…”
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The sphingolipid receptor S1PR2 is a receptor for Nogo-a repressing synaptic plasticity by Kempf, Anissa, Tews, Bjoern, Arzt, Michael E, Weinmann, Oliver, Obermair, Franz J, Pernet, Vincent, Zagrebelsky, Marta, Delekate, Andrea, Iobbi, Cristina, Zemmar, Ajmal, Ristic, Zorica, Gullo, Miriam, Spies, Peter, Dodd, Dana, Gygax, Daniel, Korte, Martin, Schwab, Martin E

“…Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and…”
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APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP by Weyer, Sascha W, Klevanski, Maja, Delekate, Andrea, Voikar, Vootele, Aydin, Dorothee, Hick, Meike, Filippov, Mikhail, Drost, Natalia, Schaller, Kristin L, Saar, Martina, Vogt, Miriam A, Gass, Peter, Samanta, Ayan, Jäschke, Andres, Korte, Martin, Wolfer, David P, Caldwell, John H, Müller, Ulrike C

“…Despite its key role in Alzheimer pathogenesis, the physiological function(s) of the amyloid precursor protein (APP) and its proteolytic fragments are still…”
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Satb2 determines miRNA expression and long-term memory in the adult central nervous system by Jaitner, Clemens, Reddy, Chethan, Abentung, Andreas, Whittle, Nigel, Rieder, Dietmar, Delekate, Andrea, Korte, Martin, Jain, Gaurav, Fischer, Andre, Sananbenesi, Farahnaz, Cera, Isabella, Singewald, Nicolas, Dechant, Georg, Apostolova, Galina

“…is a risk locus for schizophrenia and encodes a DNA-binding protein that regulates higher-order chromatin configuration. In the adult brain Satb2 is almost…”
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Heterogeneity and Development of Fine Astrocyte Morphology Captured by Diffraction-Limited Microscopy by Minge, Daniel, Domingos, Cátia, Unichenko, Petr, Behringer, Charlotte, Pauletti, Alberto, Anders, Stefanie, Herde, Michel K., Delekate, Andrea, Gulakova, Polina, Schoch, Susanne, Petzold, Gabor C., Henneberger, Christian

“…The fine processes of single astrocytes can contact many thousands of synapses whose function they can modulate through bi-directional signaling. The spatial…”
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Metabotropic P2Y1 receptor signalling mediates astrocytic hyperactivity in vivo in an Alzheimer’s disease mouse model by Delekate, Andrea, Füchtemeier, Martina, Schumacher, Toni, Ulbrich, Cordula, Foddis, Marco, Petzold, Gabor C.

“…Astrocytic network alterations have been reported in Alzheimer’s disease (AD), but the underlying pathways have remained undefined. Here we measure astrocytic…”
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The honeycomb maze provides a novel test to study hippocampal-dependent spatial navigation by Wood, Ruth A., Bauza, Marius, Krupic, Julija, Burton, Stephen, Delekate, Andrea, Chan, Dennis, O’Keefe, John

“…A newly designed honeycomb maze presents several advantages over current spatial navigation assays that include greater control over the rat’s choices…”
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Author Correction: The honeycomb maze provides a novel test to study hippocampal-dependent spatial navigation by Wood, Ruth A., Bauza, Marius, Krupic, Julija, Burton, Stephen, Delekate, Andrea, Chan, Dennis, O’Keefe, John

“…An amendment to this paper has been published and can be accessed via a link at the top of the paper…”
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Local Resting Ca 2+ Controls the Scale of Astroglial Ca 2+ Signals by King, Claire M, Bohmbach, Kirsten, Minge, Daniel, Delekate, Andrea, Zheng, Kaiyu, Reynolds, James, Rakers, Cordula, Zeug, Andre, Petzold, Gabor C, Rusakov, Dmitri A, Henneberger, Christian

“…Astroglia regulate neurovascular coupling while engaging in signal exchange with neurons. The underlying cellular machinery is thought to rely on astrocytic Ca…”
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The Sphingolipid Receptor S1PR2 Is a Receptor for Nogo-A Repressing Synaptic Plasticity: e1001763 by Kempf, Anissa, Tews, Bjoern, Arzt, Michael E, Weinmann, Oliver, Obermair, Franz J, Pernet, Vincent, Zagrebelsky, Marta, Delekate, Andrea, Iobbi, Cristina, Zemmar, Ajmal, Ristic, Zorica, Gullo, Miriam, Spies, Peter, Dodd, Dana, Gygax, Daniel, Korte, Martin, Schwab, Martin E

“…Nogo-A is a membrane protein of the central nervous system (CNS) restricting neurite growth and synaptic plasticity via two extracellular domains: Nogo-66 and…”
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NLRP3 is activated in Alzheimer´s disease and contributes to pathology in APP/PS1 mice by Heneka, Michael T., Kummer, Markus P., Stutz, Andrea, Delekate, Andrea, Schwartz, Stephanie, Saecker, Ana, Griep, Angelika, Axt, Daisy, Remus, Anita, Tzeng, Te-Chen, Gelpi, Ellen, Halle, Annett, Korte, Martin, Latz, Eicke, Golenbock, Douglas

“…Alzheimer´s Disease (AD) is the world’s most common dementing illness. Deposition of amyloid beta peptide (Aβ) drives cerebral neuroinflammation by activating…”
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APP and APLP2 are essential at PNS and CNS synapses for transmission, spatial learning and LTP by Weyer, Sascha W, Klevanski, Maja, Delekate, Andrea, Voikar, Vootele, Aydin, Dorothee, Hick, Meike, Filippov, Mikhail, Drost, Natalia, Schaller, Kristin L, Saar, Martina, Vogt, Miriam A, Gass, Peter, Samanta, Ayan, Jäschke, Andres, Korte, Martin, Wolfer, David P, Caldwell, John H, Müller, Ulrike C

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Genetic dissection of APP gene family for synaptic function, learning and memory by Mueller, Ulrike, Klevanski, Maja, Weyer, Sascha, Hick, Meike, Delekate, Andrea, Aydin, Dorothee, Schaller, Kristin, Korte, Martin, Wolfer, David, Caldwell, John, Voikar, Vootele

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O1‐03‐04: Genetic dissection of APP gene family for synaptic function, learning and memory by Mueller, Ulrike, Klevanski, Maja, Weyer, Sascha, Hick, Meike, Delekate, Andrea, Aydin, Dorothee, Schaller, Kristin, Korte, Martin, Wolfer, David, Caldwell, John, Voikar, Vootele

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