Search Results - "Delehanty, James. B"

Recent Progress in Bioconjugation Strategies for Liposome-Mediated Drug Delivery by Almeida, Bethany, Nag, Okhil K, Rogers, Katherine E, Delehanty, James B

“…In nanoparticle (NP)-mediated drug delivery, liposomes are the most widely used drug carrier, and the only NP system currently approved by the FDA for clinical…”
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Semiconductor Quantum Dots in Bioanalysis: Crossing the Valley of Death by RUSS ALGAR, W, SUSUMU, Kimihiro, DELEHANTY, James B, MEDINTZ, Igor L

“…Colloidal semiconductor quantum dots (QDs) have evolved beyond scientific novelties and are transitioning into bona fide analytical tools. We describe the…”
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Active Cellular and Subcellular Targeting of Nanoparticles for Drug Delivery by Nag, Okhil K., Delehanty, James B.

“…Nanoparticle (NP)-mediated drug delivery (NMDD) for active targeting of diseases is a primary goal of nanomedicine. NPs have much to offer in overcoming the…”
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Peptides for Specifically Targeting Nanoparticles to Cellular Organelles: Quo Vadis? by Field, Lauren D, Delehanty, James B, Chen, YungChia, Medintz, Igor L

“…The interfacing of nanomaterials and especially nanoparticles within all aspects of biological research continues to grow at a nearly unabated pace with…”
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Evaluating the potential of using quantum dots for monitoring electrical signals in neurons by Efros, Alexander L., Delehanty, James B., Huston, Alan L., Medintz, Igor L., Barbic, Mladen, Harris, Timothy D.

“…Success in the projects aimed at providing an advanced understanding of the brain is directly predicated on making critical advances in nanotechnology. This…”
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Enhancing the Stability and Biological Functionalities of Quantum Dots via Compact Multifunctional Ligands by Susumu, Kimihiro, Uyeda, H. Tetsuo, Medintz, Igor L, Pons, Thomas, Delehanty, James B, Mattoussi, Hedi

“…We have designed and synthesized a series of modular ligands based on poly(ethylene glycol) (PEG) coupled with functional terminal groups to promote…”
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Quantum-dot/dopamine bioconjugates function as redox coupled assemblies for in vitro and intracellular pH sensing by Medintz, Igor L, Mattoussi, Hedi, Stewart, Michael H, Trammell, Scott A, Susumu, Kimihiro, Delehanty, James B, Mei, Bing C, Melinger, Joseph S, Blanco-Canosa, Juan B, Dawson, Philip E

“…The use of semiconductor quantum dots (QDs) for bioimaging and sensing has progressively matured over the past decade. QDs are highly sensitive to…”
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Purple‑, Blue‑, and Green-Emitting Multishell Alloyed Quantum Dots: Synthesis, Characterization, and Application for Ratiometric Extracellular pH Sensing by Susumu, Kimihiro, Field, Lauren D, Oh, Eunkeu, Hunt, Michael, Delehanty, James B, Palomo, Valle, Dawson, Philip E, Huston, Alan L, Medintz, Igor L

“…We report the synthesis of a series of Cd x Zn1–x Se/Cd y Zn1–y S/ZnS and ZnSe/Cd y Zn1–y S/ZnS multishell alloyed luminescent semiconductor quantum dots (QDs)…”
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Cellular Uptake and Fate of PEGylated Gold Nanoparticles Is Dependent on Both Cell-Penetration Peptides and Particle Size by Oh, Eunkeu, Delehanty, James B, Sapsford, Kim E, Susumu, Kimihiro, Goswami, Ramasis, Blanco-Canosa, Juan B, Dawson, Philip E, Granek, Jessica, Shoff, Megan, Zhang, Qin, Goering, Peter L, Huston, Alan, Medintz, Igor L

“…Numerous studies have examined how the cellular delivery of gold nanoparticles (AuNPs) is influenced by different physical and chemical characteristics;…”
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Multifunctional Compact Zwitterionic Ligands for Preparing Robust Biocompatible Semiconductor Quantum Dots and Gold Nanoparticles by Susumu, Kimihiro, Oh, Eunkeu, Delehanty, James B, Blanco-Canosa, Juan B, Johnson, Brandy J, Jain, Vaibhav, Hervey, William Judson, Algar, W. Russ, Boeneman, Kelly, Dawson, Philip E, Medintz, Igor L

“…We describe the synthesis of a series of four different ligands which are used to prepare hydrophilic, biocompatible luminescent quantum dots (QDs) and gold…”
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Nanoparticle-Mediated Visualization and Control of Cellular Membrane Potential: Strategies, Progress, and Remaining Issues by Nag, Okhil K, Muroski, Megan E, Hastman, David A, Almeida, Bethany, Medintz, Igor L, Huston, Alan L, Delehanty, James B

“…The interfacing of nanoparticle (NP) materials with cells, tissues, and organisms for a range of applications including imaging, sensing, and drug delivery…”
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Special Issue “Nanoparticle-Mediated Drug Delivery, Imaging, and Control of Cellular Functions” by Nag, Okhil K, Delehanty, James B

“…Over the past several decades, nanoparticles (NPs) have shown promising capabilities in the field of medicine for their applications as vehicles for targeted…”
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Fusogenic Liposomes for the Intracellular Delivery of Phosphocreatine by Nag, Okhil K, Oh, Eunkeu, Delehanty, James B

“…Maintaining intracellular adenosine triphosphate (ATP) levels is essential for numerous cellular functions, including energy metabolism, muscle contraction,…”
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A New Family of Pyridine-Appended Multidentate Polymers As Hydrophilic Surface Ligands for Preparing Stable Biocompatible Quantum Dots by Susumu, Kimihiro, Oh, Eunkeu, Delehanty, James B, Pinaud, Fabien, Gemmill, Kelly Boeneman, Walper, Scott, Breger, Joyce, Schroeder, Maria J, Stewart, Michael H, Jain, Vaibhav, Whitaker, Craig M, Huston, Alan L, Medintz, Igor L

“…The growing utility of semiconductor quantum dots (QDs) in biochemical and cellular research necessitates, in turn, continuous development of surface…”
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Quantitative Imaging of Protein Secretions from Single Cells in Real Time by Raphael, Marc P., Christodoulides, Joseph A., Delehanty, James B., Long, James P., Byers, Jeff M.

“…Protein secretions from individual cells create spatially and temporally varying concentration profiles in the extracellular environment, which guide a wide…”
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Reactive Semiconductor Nanocrystals for Chemoselective Biolabeling and Multiplexed Analysis by Jennings, Travis L, Becker-Catania, Sara G, Triulzi, Robert C, Tao, Guoliang, Scott, Bradley, Sapsford, Kim E, Spindel, Samantha, Oh, Eunkeu, Jain, Vaibhav, Delehanty, James. B, Prasuhn, Duane E, Boeneman, Kelly, Algar, W. Russ, Medintz, Igor L

“…Effective biological application of nanocrystalline semiconductor quantum dots continues to be hampered by the lack of easily implemented and widely applicable…”
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Spatiotemporal Multicolor Labeling of Individual Cells Using Peptide-Functionalized Quantum Dots and Mixed Delivery Techniques by Delehanty, James B, Bradburne, Christopher E, Susumu, Kimihiro, Boeneman, Kelly, Mei, Bing C, Farrell, Dorothy, Blanco-Canosa, Juan B, Dawson, Philip E, Mattoussi, Hedi, Medintz, Igor L

“…Multicolor fluorescent labeling of both intra- and extracellular structures is a powerful technique for simultaneous monitoring of multiple complex biochemical…”
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Quantum dot–based multiphoton fluorescent pipettes for targeted neuronal electrophysiology by Andrásfalvy, Bertalan K, Galiñanes, Gregorio L, Huber, Daniel, Barbic, Mladen, Macklin, John J, Susumu, Kimihiro, Delehanty, James B, Huston, Alan L, Makara, Judit K, Medintz, Igor L

“…Quantum dot–coated pipettes facilitate targeted electrophysiological recordings in deep brain tissue because they are readily visible owing to the strong…”
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Liquid Crystal Nanoparticle Conjugates for Scavenging Reactive Oxygen Species in Live Cells by Nag, Okhil K, Naciri, Jawad, Lee, Kwahun, Oh, Eunkeu, Almeida, Bethany, Delehanty, James B

“…The elevated intracellular production of or extracellular exposure to reactive oxygen species (ROS) causes oxidative stress to cells, resulting in deleterious…”
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Cholesterol Functionalization of Gold Nanoparticles Enhances Photoactivation of Neural Activity by Carvalho-de-Souza, Joao L, Nag, Okhil K, Oh, Eunkeu, Huston, Alan L, Vurgaftman, Igor, Pepperberg, David R, Bezanilla, Francisco, Delehanty, James B

“…Gold nanoparticles (AuNPs) attached to the extracellular leaflet of the plasma membrane of neurons can enable the generation of action potentials (APs) in…”
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