Search Results - "Delclos, K. B."

Mass spectrometric determination of Genistein tissue distribution in diet-exposed Sprague-Dawley rats by Chang, H C, Churchwell, M I, Delclos, K B, Newbold, R R, Doerge, D R

“…Genistein, the principal soy isoflavone, was administered in the diet to male and female Sprague-Dawley rats as part of a multigeneration study of potential…”
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Effect of dietary administration of genistein, nonylphenol or ethinyl estradiol on hepatic testosterone metabolism, cytochrome P-450 enzymes, and estrogen receptor alpha expression by Laurenzana, E.M, Weis, C.C, Bryant, C.W, Newbold, R, Delclos, K.B

“…The objective of this study was to examine effects of estrogenic agents of varying potencies (genistein, p-nonylphenol, and ethinyl estradiol) on hepatic…”
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A two-year toxicology study of bisphenol A (BPA) in Sprague-Dawley rats: CLARITY-BPA core study results by Camacho, L., Lewis, S.M., Vanlandingham, M.M., Olson, G.R., Davis, K.J., Patton, R.E., Twaddle, N.C., Doerge, D.R., Churchwell, M.I., Bryant, M.S., McLellen, F.M., Woodling, K.A., Felton, R.P., Maisha, M.P., Juliar, B.E., Gamboa da Costa, G., Delclos, K.B.

“…We report the data from the guideline-compliant two-year toxicology study conducted as part of the Consortium Linking Academic and Regulatory Insights on…”
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Nonylphenol alters the activity of splenic NK cells and the numbers of leukocyte subpopulations in Sprague–Dawley rats: a two-generation feeding study by Karrow, N.A, Guo, T.L, Delclos, K.B, Newbold, R.R, Weis, C, Germolec, D.R, White, K.L, McCay, J.Ann

“…Nonylphenol (NP) has been identified at low levels in surface waters throughout North America. This industrial chemical is primarily used for the production of…”
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Myelotoxicity in genistein-, nonylphenol-, methoxychlor-, vinclozolin- or ethinyl estradiol-exposed F1 generations of Sprague-Dawley rats following developmental and adult exposures by GUO, T. L, GERMOLEC, D. R, MUSGROVE, D. L, DELCLOS, K. B, NEWBOLD, R. R, WEIS, C, WHITE, K. L

“…The myelotoxicity of five endocrine active chemicals was evaluated in F1 generation of Sprague-Dawley rats following developmental and adult exposures at three…”
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Long term dietary methoxychlor exposure in rats increases sodium solution consumption but has few effects on other sexually dimorphic behaviors by Flynn, K.M., Delclos, K.B., Newbold, R.R., Ferguson, S.A.

“…Methoxychlor is an insecticide with estrogen-like activity, thus exposure during development might cause sexually dimorphic behavioral alterations. To evaluate…”
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Increased Volume of the Calbindin D28k-Labeled Sexually Dimorphic Hypothalamus in Genistein and Nonylphenol-Treated Male Rats by Scallet, A. C., Divine, R. L., Newbold, R. R., Delclos, K. B.

“…The adult rat brain develops through an interplay of neuronal proliferation and programmed cell death. Steroid hormones and growth factors may alter the…”
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Effects of genistein exposure on sexually dimorphic behaviors in rats by FLYNN, K. M, FERGUSON, S. A, DELCLOS, K. B, NEWBOLD, R. R

“…The phytoestrogen genistein, the principal isoflavone in soybeans, has adverse effects on animal reproduction. As adult physiology and behavior are sensitive…”
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Polycystic kidney disease induced in F1 Sprague-Dawley rats fed para-nonylphenol in a soy-free, casein-containing diet by LATENDRESSE, J. R, NEWBOLD, R. R, WEIS, C. C, DELCLOS, K. B

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A comparison of the inflammatory response to a polydimethylsiloxane implant in male and female Balb/c mice by DALU, A, BLAYDES, B. S, LOMAX, L. G, DELCLOS, K. B

“…The implantation of biomaterials elicits a host response that influences the long-term behavior of implanted medical devices. This foreign body response is…”
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A comment on the discussion and application of statistical methods in Mandrup et al. Low‐dose effects of bisphenol A on mammary gland development in rats (Andrology 4: 673–683, 2016) by Felton, R. P., Juliar, B. E., Olson, G. R., Delclos, K. B.

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Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague–Dawley rats by Latendresse, John R., Bucci, Thomas J., Olson, Greg, Mellick, Paul, Weis, Constance C., Thorn, Brett, Newbold, Retha R., Delclos, K. Barry

“…Genistein and ethinyl estradiol (EE 2) were examined in multigenerational reproductive and 2-yr chronic toxicity studies with different exposure durations…”
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Multigenerational exposure to dietary genistein has no severe effects on nursing behavior in rats by Flynn, K M, Ferguson, S A, Delclos, K B, Newbold, R R

“…The phytoestrogen and principal isoflavone in soy, genistein, has adverse effects on reproductive physiology in rodents. Since physiology and behavior are both…”
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Differences in the response to oxidative stress and mutant frequency in CD (Sprague-Dawley) and Fisher 344 rats due to an induced inflammatory response by Sams II, R., Blaydes, B., Warbritton, A., Lomax, L. G., Bucci, T., Delclos, K. B.

“…In this study, the rodent air pouch model was used to examine the production and processing of oxidative DNA damage in two strains of rats commonly used in…”
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Effects of dietary genistein exposure during development on male and female CD (Sprague-Dawley) rats by Delclos, K.Barry, Bucci, Thomas J, Lomax, Larry G, Latendresse, John R, Warbritton, Alan, Weis, Constance C, Newbold, Retha R

“…Genistein is a naturally occurring isoflavone that interacts with estrogen receptors and multiple other molecular targets. Human exposure to genistein is…”
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NTP toxicity report of reproductive dose range-finding study of Genistein (CAS No. 446-72-0) administered in feed to Sprague-Dawley rats by Delclos, K B, Newbold, Retha

“…Genistein is a naturally occurring isoflavone that interacts with estrogen receptors and multiple other molecular targets. Human exposure to genistein is…”
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Metabolism and DNA binding of the environmental colon carcinogen 6-nitrochrysene in rats by YOUNG-HEUM CHAE, DELCLOS, K. B, BLAYDES, B, KARAM EL-BAYOUMY

“…The environmental contaminant 6-nitrochrysene (6-NC) has been shown to induce adenomas and adenocarcinomas in the colons of rats. The present study aimed at…”
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Relationships of DNA adduct formation, K-ras activating mutations and tumorigenic activities of 6-nitrochrysene and its metabolites in the lungs of CD-1 mice by Li, E E, Heflich, R H, Bucci, T J, Manjanatha, M G, Blaydes, B S, Delclos, K B

“…6-Nitrochrysene (6-NC), an environmental pollutant and a potent mouse lung carcinogen, is activated by two major metabolic pathways to yield DNA adducts…”
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Metabolism of 6-nitrochrysene by intestinal microflora by MANNING, B. W, CAMPBELL, W. L, FRANKLIN, W, DELCLOS, K. B, CERNIGLIA, C. E

“…Classifications Services AEM Citing Articles Google Scholar PubMed Related Content Social Bookmarking CiteULike Delicious Digg Facebook Google+ Mendeley Reddit…”
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Placental transfer of the soy isoflavone genistein following dietary and gavage administration to Sprague Dawley rats by Doerge, Daniel R., Churchwell, Mona I., Chang, Hebron C., Newbold, Retha R., Delclos, K.Barry

“…Genistein, the principal soy isoflavone, has estrogenic activity and is widely consumed by humans for putative beneficial health effects. The goal of the…”
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