Search Results - "Delclos, K Barry"

Investigation of the effects of subchronic low dose oral exposure to bisphenol A (BPA) and ethinyl estradiol (EE) on estrogen receptor expression in the juvenile and adult female rat hypothalamus by Rebuli, Meghan E, Cao, Jinyan, Sluzas, Emily, Delclos, K Barry, Camacho, Luísa, Lewis, Sherry M, Vanlandingham, Michelle M, Patisaul, Heather B

“…Concerns have been raised regarding the long-term impacts of early life exposure to the ubiquitous environmental contaminant bisphenol A (BPA) on brain…”
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Lactational transfer of bisphenol A in Sprague–Dawley rats by Doerge, Daniel R., Vanlandingham, Michelle, Twaddle, Nathan C., Delclos, K. Barry

“…Bisphenol A (BPA), an important industrial chemical to which humans are exposed on a daily basis, has long been associated with endocrine disruption in…”
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Genistein and ethinyl estradiol dietary exposure in multigenerational and chronic studies induce similar proliferative lesions in mammary gland of male Sprague–Dawley rats by Latendresse, John R., Bucci, Thomas J., Olson, Greg, Mellick, Paul, Weis, Constance C., Thorn, Brett, Newbold, Retha R., Delclos, K. Barry

“…Genistein and ethinyl estradiol (EE 2) were examined in multigenerational reproductive and 2-yr chronic toxicity studies with different exposure durations…”
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Mass spectrometric determination of Genistein tissue distribution in diet-exposed Sprague-Dawley rats by Chang, H C, Churchwell, M I, Delclos, K B, Newbold, R R, Doerge, D R

“…Genistein, the principal soy isoflavone, was administered in the diet to male and female Sprague-Dawley rats as part of a multigeneration study of potential…”
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Effects of intravenous and oral di(2-ethylhexyl) phthalate (DEHP) and 20% Intralipid vehicle on neonatal rat testis, lung, liver, and kidney by Camacho, Luísa, Latendresse, John R., Muskhelishvili, Levan, Law, Charles D., Delclos, K. Barry

“…The highest human exposures to the plasticizer di(2-ethylhexyl) phthalate (DEHP) occur through intravenous (iv) exposure from medical procedures. Rodent…”
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Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90 by Delclos, K. Barry, Camacho, Luísa, Lewis, Sherry M., Vanlandingham, Michelle M., Latendresse, John R., Olson, Greg R., Davis, Kelly J., Patton, Ralph E., da Costa, Gonçalo Gamboa, Woodling, Kellie A., Bryant, Matthew S., Chidambaram, Mani, Trbojevich, Raul, Juliar, Beth E., Felton, Robert P., Thorn, Brett T.

“…Bisphenol A (BPA) is a high production volume industrial chemical to which there is widespread human oral exposure. Guideline studies used to set regulatory…”
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Re: Historical Perspective: Bisphenol A and Phthalates: How Environmental Chemicals Are Reshaping Toxicology by Delclos, K Barry, Camacho, Luísa, Gamboa da Costa, Gonçalo

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Comparison of Life-Stage-Dependent Internal Dosimetry for Bisphenol A, Ethinyl Estradiol, a Reference Estrogen, and Endogenous Estradiol to Test an Estrogenic Mode of Action in Sprague Dawley Rats by Churchwell, Mona I., Camacho, Luísa, Vanlandingham, Michelle M., Twaddle, Nathan C., Sepehr, Estatira, Delclos, K. Barry, Fisher, Jeffrey W., Doerge, Daniel R.

“…Bisphenol A (BPA) was administered by gavage (2.5–300,000 μg/kg body weight (bw)/day) to pregnant Sprague Dawley dams, newborn pups, and continuing into…”
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NIEHS/FDA CLARITY-BPA research program update by Heindel, Jerrold J., Newbold, Retha R., Bucher, John R., Camacho, Luísa, Delclos, K. Barry, Lewis, Sherry M., Vanlandingham, Michelle, Churchwell, Mona I., Twaddle, Nathan C., McLellen, Michelle, Chidambaram, Mani, Bryant, Matthew, Woodling, Kellie, Costa, Gonçalo Gamboa da, Ferguson, Sherry A., Flaws, Jodi, Howard, Paul C., Walker, Nigel J., Zoeller, R. Thomas, Fostel, Jennifer, Favaro, Carolyn, Schug, Thaddeus T.

“…Bisphenol A (BPA) is a chemical used in the production of numerous consumer products resulting in potential daily human exposure to this chemical. The FDA…”
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Few effects of multi-generational dietary exposure to genistein or nonylphenol on sodium solution intake in male and female Sprague–Dawley rats by Ferguson, Sherry A, Delclos, K. Barry, Newbold, Retha R, Flynn, Katherine M

“…Abstract Previous work in our laboratory indicated that lifelong dietary exposure to estrogen-like endocrine disrupters increased sodium solution intake in…”
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A new approach to synergize academic and guideline-compliant research: The CLARITY-BPA research program by Schug, Thaddeus T., Heindel, Jerrold J., Camacho, Luísa, Delclos, K. Barry, Howard, Paul, Johnson, Anne F., Aungst, Jason, Keefe, Dennis, Newbold, Retha, Walker, Nigel J., Thomas Zoeller, R., Bucher, John R.

“…Recently, medical research has seen a strong push toward translational research, or “bench to bedside” collaborations, that strive to enhance the utility of…”
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Response to Hunt et al., invalid controls undermine conclusions of FDA studies by Delclos, K Barry, Doerge, Daniel R

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Determination using liquid-chromatography–electrospray tandem mass spectroscopy of ethinylestradiol serum pharmacokinetics in adult Sprague–Dawley rats by Twaddle, Nathan C., Churchwell, Mona I., Newbold, Retha R., Delclos, K.Barry, Doerge, Daniel R.

“…The pharmacokinetics of ethinylestradiol (EE2), a potent synthetic estrogen, was investigated in male and female Sprague–Dawley rats as part of a series of…”
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Effects of oral exposure to bisphenol A on gene expression and global genomic DNA methylation in the prostate, female mammary gland, and uterus of NCTR Sprague-Dawley rats by Camacho, Luísa, Basavarajappa, Mallikarjuna S., Chang, Ching-Wei, Han, Tao, Kobets, Tetyana, Koturbash, Igor, Surratt, Gordon, Lewis, Sherry M., Vanlandingham, Michelle M., Fuscoe, James C., Gamboa da Costa, Gonçalo, Pogribny, Igor P., Delclos, K. Barry

“…•The effects of seven “low BPA”, two “high BPA”, and two EE2 doses versus vehicle control were assessed at the molecular level.•Prostate and mammary glands,…”
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Comparison of endpoints relevant to toxicity assessments in 3 generations of CD-1 mice fed irradiated natural and purified ingredient diets with varying soy protein and isoflavone contents by Camacho, Luísa, Lewis, Sherry M., Vanlandingham, Michelle M., Juliar, Beth E., Olson, Greg R., Patton, Ralph E., Gamboa da Costa, Gonçalo, Woodling, Kellie, Sepehr, Estatira, Bryant, Matthew S., Doerge, Daniel R., Basavarajappa, Mallikarjuna S., Felton, Robert P., Delclos, K. Barry

“…Diet is an important variable in toxicology. There are mixed reports on the impact of soy components on energy utilization, fat deposition, and reproductive…”
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Advancing human health risk assessment by Lanzoni, Anna, Castoldi, Anna F, Kass, George EN, Terron, Andrea, De Seze, Guilhem, Bal‐Price, Anna, Bois, Frédéric Y, Delclos, K Barry, Doerge, Daniel R, Fritsche, Ellen, Halldorsson, Thorhallur, Kolossa‐Gehring, Marike, Hougaard Bennekou, Susanne, Koning, Frits, Lampen, Alfonso, Leist, Marcel, Mantus, Ellen, Rousselle, Christophe, Siegrist, Michael, Steinberg, Pablo, Tritscher, Angelika, Van de Water, Bob, Vineis, Paolo, Walker, Nigel, Wallace, Heather, Whelan, Maurice, Younes, Maged

“…The current/traditional human health risk assessment paradigm is challenged by recent scientific and technical advances, and ethical demands. The current…”
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Overlapping but distinct effects of genistein and ethinyl estradiol (EE 2) in female Sprague–Dawley rats in multigenerational reproductive and chronic toxicity studies by Delclos, K. Barry, Weis, Constance C., Bucci, Thomas J., Olson, Greg, Mellick, Paul, Sadovova, Natalya, Latendresse, John R., Thorn, Brett, Newbold, Retha R.

“…Genistein and ethinyl estradiol (EE 2) were examined in multigenerational reproductive and chronic toxicity studies that had different treatment intervals…”
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Toxicity Evaluation of Bisphenol A Administered by Gavage to Sprague Dawley Rats From Gestation Day 6 Through Postnatal Day 90 by Delclos, K Barry, Camacho, Luísa, Lewis, Sherry M, Vanlandingham, Michelle M, Latendresse, John R, Olson, Greg R, Davis, Kelly J, Patton, Ralph E, Gamboa da Costa, Gonçalo, Woodling, Kellie A, Bryant, Matthew S, Chidambaram, Mani, Trbojevich, Raul, Juliar, Beth E, Felton, Robert P, Thorn, Brett T

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Lactational transfer of the soy isoflavone, genistein, in Sprague–Dawley rats consuming dietary genistein by Doerge, Daniel R., Twaddle, Nathan C., Churchwell, Mona I., Newbold, Retha R., Delclos, K. Barry

“…Exposures of Sprague–Dawley rats to the soy isoflavone, genistein, throughout the entire lifespan have produced a number of effects on reproductive tissues,…”
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Multigenerational exposure to ethinyl estradiol affects bone geometry, but not bone mineral density in rats by Hotchkiss, Charlotte E, Weis, Connie, Blaydes, Betty, Newbold, Retha, Delclos, K. Barry

“…Abstract Estrogenic compounds are known to prevent bone loss in ovariectomized adult rats; however, their effects on bone in developing and…”
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