Search Results - "Delcanale, Pietro"
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Super-resolution microscopy as a powerful tool to study complex synthetic materials
Published in Nature reviews. Chemistry (01-02-2019)“…Understanding the relations between the formation, structure, dynamics and functionality of complex synthetic materials is one of the great challenges in…”
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2
Force loading explains spatial sensing of ligands by cells
Published in Nature (London) (14-12-2017)“…The formation of cellular adhesion complexes is important in normal and pathological cell activity, and is determined by the force imposed by the combined…”
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Insights on the Mechanical Properties of SARS-CoV-2 Particles and the Effects of the Photosensitizer Hypericin
Published in International journal of molecular sciences (10-08-2024)“…SARS-CoV-2 is a highly pathogenic virus responsible for the COVID-19 disease. It belongs to the Coronaviridae family, characterized by a phospholipid envelope,…”
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DNA-PAINT super-resolution imaging data of surface exposed active sites on particles
Published in Data in brief (01-06-2020)“…Surface functionalization with targeting ligands confers to nanomaterials the ability of selectively recognize a biological target. Therefore, a quantitative…”
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Concanavalin A Delivers a Photoactive Protein to the Bacterial Wall
Published in International journal of molecular sciences (01-06-2024)“…Modular supramolecular complexes, where different proteins are assembled to gather targeting capability and photofunctional properties within the same…”
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A Photoactive Supramolecular Complex Targeting PD-L1 Reveals a Weak Correlation between Photoactivation Efficiency and Receptor Expression Levels in Non-Small-Cell Lung Cancer Tumor Models
Published in Pharmaceutics (01-12-2023)“…Photo-immunotherapy uses antibodies conjugated to photosensitizers to produce nanostructured constructs endowed with targeting properties and…”
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Subdiffraction localization of a nanostructured photosensitizer in bacterial cells
Published in Scientific reports (23-10-2015)“…Antibacterial treatments based on photosensitized production of reactive oxygen species is a promising approach to address local microbial infections. Given…”
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8
Nitric Oxide Sensing by a Blue Fluorescent Protein
Published in Antioxidants (01-11-2022)“…S-Nitrosylation of cysteine residues is an important molecular mechanism for dynamic, post-translational regulation of several proteins, providing a ubiquitous…”
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A Double Payload Complex between Hypericin and All- trans Retinoic Acid in the β-Lactoglobulin Protein
Published in Antibiotics (Basel) (21-02-2022)“…Combined therapies are usually used to treat since this approach can tackle various foci simultaneously. Using a combination of spectroscopic, computational,…”
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Correlating Super-Resolution Microscopy and Transmission Electron Microscopy Reveals Multiparametric Heterogeneity in Nanoparticles
Published in Nano letters (23-06-2021)“…The functionalization of nanoparticles with functional moieties is a key strategy to achieve cell targeting in nanomedicine. The interplay between size and…”
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Nanoscale Mapping Functional Sites on Nanoparticles by Points Accumulation for Imaging in Nanoscale Topography (PAINT)
Published in ACS nano (28-08-2018)“…The ability of nanoparticles to selectively recognize a molecular target constitutes the key toward nanomedicine applications such as drug delivery and…”
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Fluorescence Correlation Spectroscopy as a Versatile Method to Define Aptamer–Protein Interactions with Single-Molecule Sensitivity
Published in Analytical chemistry (Washington) (09-01-2024)“…Aptamers are folded oligonucleotides that selectively recognize and bind a target and are consequently regarded as an emerging alternative to antibodies for…”
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Aptamers with Tunable Affinity Enable Single‐Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells
Published in Angewandte Chemie International Edition (12-10-2020)“…Tumor cell‐surface markers are usually overexpressed or mutated protein receptors for which spatiotemporal regulation differs between and within cancers…”
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14
Photosensitizers against pathogens: Model membranes characterization with hypericin
Published in Biophysical journal (10-02-2023)Get full text
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Versatile Supramolecular Complex for Targeted Antimicrobial Photodynamic Inactivation
Published in Bioconjugate chemistry (20-04-2022)“…We report the development of a supramolecular structure endowed with photosensitizing properties and targeting capability for antimicrobial photodynamic…”
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The Interaction of Hypericin with SARS-CoV-2 Reveals a Multimodal Antiviral Activity
Published in ACS applied materials & interfaces (30-03-2022)“…Hypericin is a photosensitizing drug that is active against membrane-enveloped viruses and therefore constitutes a promising candidate for the treatment of…”
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Nanoscale Mapping of Recombinant Viral Proteins: From Cells to Virus-Like Particles
Published in ACS photonics (19-01-2022)“…Influenza recombinant proteins and virus-like particles (VLPs) play an important role in vaccine development (e.g., CadiFlu-S). However, their production from…”
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Hypericin–Apomyoglobin: An Enhanced Photosensitizer Complex for the Treatment of Tumor Cells
Published in Biomacromolecules (13-05-2019)“…Bioavailability of photosensitizers for cancer photodynamic therapy is often hampered by their low solubility in water. Here, we overcome this issue by using…”
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Photodynamic action of Hypericum perforatum hydrophilic extract against Staphylococcus aureus
Published in Photochemical & photobiological sciences (01-03-2020)“…Hypericin (Hyp) is one of the most effective, naturally occurring photodynamic agents, which proved effective against a wide array of microorganisms. One…”
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Back Cover: Aptamers with Tunable Affinity Enable Single‐Molecule Tracking and Localization of Membrane Receptors on Living Cancer Cells (Angew. Chem. Int. Ed. 42/2020)
Published in Angewandte Chemie International Edition (12-10-2020)“…Rational engineering of low‐affinity aptamers expands the toolkit of affinity probes for super‐resolution microscopy. In their Research Article on page 18546,…”
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