Search Results - "Delbaere, Joke"
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MCT8 deficiency in Purkinje cells disrupts embryonic chicken cerebellar development
Published in Journal of endocrinology (01-02-2017)“…Inactivating mutations in the human SLC16A2 gene encoding the thyroid hormone transporter monocarboxylate transporter 8 (MCT8) result in the…”
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Regulators of thyroid hormone availability and action in embryonic chicken brain development
Published in General and comparative endocrinology (01-09-2013)“…Highlights • Review on thyroid hormone (TH) regulation in the early embryonic avian brain. • Intracellular TH action is regulated by transporters, deiodinases…”
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The affinity of transthyretin for T3 or T4 does not determine which form of the hormone accumulates in the choroid plexus
Published in General and comparative endocrinology (01-08-2018)“…•TTR, D3 and OATP1C1 mRNAs were almost exclusively expressed in the choroid plexus.•D1, MCT8 & MCT10 mRNA levels were higher in choroid plexus than other brain…”
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Characterization of Chicken Thyroid Hormone Transporters
Published in Endocrinology (Philadelphia) (01-06-2016)“…Thyroid hormone (TH) transmembrane transporters are key regulators of TH availability in target cells where correct TH signaling is essential for normal…”
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Expression of thyroid hormone transporters and deiodinases at the brain barriers in the embryonic chicken: Insights into the regulation of thyroid hormone availability during neurodevelopment
Published in General and comparative endocrinology (01-04-2015)“…Highlights • Embryonic expression of thyroid hormone transporters and deiodinases was studied. • LAT1 and D2 are expressed in brain microvessels forming the…”
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Expression profile and thyroid hormone responsiveness of transporters and deiodinases in early embryonic chicken brain development
Published in Molecular and cellular endocrinology (26-02-2012)“…► TH transporters and deiodinases are expressed in early embryonic chicken brain. ► Their expression pattern is dynamic and region specific. ► Injection of THs…”
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The affinity of transthyretin for T 3 or T 4 does not determine which form of the hormone accumulates in the choroid plexus
Published in General and comparative endocrinology (01-08-2018)“…Normal development of the brain is dependent on the required amounts of thyroid hormones (THs) reaching specific regions of the brain during each stage of…”
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Mosaic Expression of Thyroid Hormone Regulatory Genes Defines Cell Type-Specific Dependency in the Developing Chicken Cerebellum
Published in Cerebellum (London, England) (01-12-2016)“…The cerebellum is a morphologically unique brain structure that requires thyroid hormones (THs) for the correct coordination of key cellular events driving its…”
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