Search Results - "Delayen, Aurélie"

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    Synthesis and biological evaluation of a new family of anti-benzylanilinosulfonamides as CA IX inhibitors by Thiry, Anne, Delayen, Aurélie, Goossens, Laurence, Houssin, Raymond, Ledecq, Marie, Frankart, Aurélie, Dogné, Jean-Michel, Wouters, Johan, Supuran, Claudiu T., Hénichart, Jean-Pierre, Masereel, Bernard

    Published in European journal of medicinal chemistry (01-02-2009)
    “…We report the synthesis and the pharmacological evaluation of a new class of human carbonic anhydrase (hCA) inhibitors prepared regio- and stereoselectively by…”
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    (2RS,5SR,6SR)-Methyl 4-{cis-2-[3-fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxy­methyl]-6-hydroxy-3-phenylmorpholino}­benzene­sulfinate by Charlier, Caroline, Delayen, Aurelie, Norberg, Bernadette, Hénichart, Jean-Pierre, Wouters, Johan

    “…The title compound, C30H34FNO7S, is a key inter­mediate in the design of dual 5‐LOX (5‐lipoxygenase)/COX‐2 (cyclo­oxygenase‐2) inhibitors. The compound…”
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    (2RS,5SR,6SR)-Methyl 4-{cis-2-[3-fluoro-5-(4-methoxy-3,4,5,6-tetrahydro-2H-pyran-4-yl)phenoxymethyl]-6-hydroxy-3-phenylmorpholino}-benzenesulfinate by CHARLIER, Caroline, DELAYEN, Aurelie, NORBERG, Bernadette, HENICHART, Jean-Pierre, WOUTERS, Johan

    “…The title compound, C30H34FNO7S, is a key intermediate in the design of dual 5-LOX (5-lipoxygenase)/COX-2 (cyclooxygenase-2) inhibitors. The compound…”
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    Journal Article