Search Results - "Delattre, J Y"

IDH1 or IDH2 mutations predict longer survival and response to temozolomide in low-grade gliomas by HOUILLIER, C, WANG, X, HOANG-XUAN, K, SANSON, M, DELATTRE, J.-Y, KALOSHI, G, MOKHTARI, K, GUILLEVIN, R, LAFFAIRE, J, PARIS, S, BOISSELIER, B, IDBAIH, A, LAIGLE-DONADEY, F

“…Recent studies have shown that IDH1 and IDH2 mutations occur frequently in gliomas, including low-grade gliomas. However, their impact on the prognosis and…”
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All the 1p19q codeleted gliomas are mutated on IDH1 or IDH2 by LABUSSIERE, M, IDBAIH, A, DUCRAY, F, EL HALLANI, S, MOKHTARI, K, HOANG-XUAN, K, DELATTRE, J.-Y, SANSON, M, WANG, X.-W, MARIE, Y, BOISSELIER, B, FALET, C, PARIS, S, LAFFAIRE, J, CARPENTIER, C, CRINIERE, E

“…Recently, the gene encoding the human cytosolic NADPH-dependent isocitrate dehydrogenase (IDH1) was reported frequently mutated in gliomas. Rare mutations were…”
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TERT promoter mutations in gliomas, genetic associations and clinico-pathological correlations by Labussière, M, Di Stefano, A L, Gleize, V, Boisselier, B, Giry, M, Mangesius, S, Bruno, A, Paterra, R, Marie, Y, Rahimian, A, Finocchiaro, G, Houlston, R S, Hoang-Xuan, K, Idbaih, A, Delattre, J-Y, Mokhtari, K, Sanson, M

“…Background: The role of telomerase reverse transcriptase ( TERT ) in gliomagenesis has been recently further strengthened by the frequent occurrence of TERT…”
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Seronegative paraneoplastic cerebellar degeneration: the PNS Euronetwork experience by Ducray, F., Demarquay, G., Graus, F., Decullier, E., Antoine, J.-C., Giometto, B., Psimaras, D., Delattre, J.-Y., Carpentier, A. F., Honnorat, J.

“…Background and purpose To describe the characteristics of patients presenting a paraneoplastic cerebellar degeneration without classical onconeural antibodies…”
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Glioma tumor grade correlates with parkin depletion in mutant p53-linked tumors and results from loss of function of p53 transcriptional activity by Viotti, J, Duplan, E, Caillava, C, Condat, J, Goiran, T, Giordano, C, Marie, Y, Idbaih, A, Delattre, J-Y, Honnorat, J, Checler, F, Alves da Costa, C

“…Gliomas represent the most frequent form of primary brain tumors in adults, the prognosis of which remains extremely poor. Inactivating mutations on the tumor…”
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Temozolomide for low-grade gliomas: Predictive impact of 1p/19q loss on response and outcome by KALOSHI, G, BENOUAICH-AMIEL, A, CAPELLE, L, DUFFAU, H, CORNU, P, SIMON, J.-M, MOKHTARI, K, POLIVKA, M, OMURO, A, CARPENTIER, A, SANSON, M, DELATTRE, J.-Y, DIAKITE, F, HOANG-XUAN, K, TAILLIBERT, S, LEJEUNE, J, LAIGLE-DONADEY, F, RENARD, M.-A, IRAQI, W, IDBAIH, A, PARIS, S

“…To evaluate the predictive impact of chromosome 1p/19q deletions on the response and outcome of progressive low-grade gliomas (LGG) treated with up-front…”
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Adult brainstem glioma presenting with isolated persistent hemifacial spasm or facial nerve palsy by Dudoit, T., Balossier, A., Reyes-Botero, G., Laigle-Donadey, F., Emery, E., Blond, S., Carluer, L., Lechapt-Zalcman, E., Delattre, J.-Y., Guillamo, J.-S.

“…Adult brainstem gliomas are a rare group of heterogeneous brain tumors. Classical clinical presentation includes progressive impairment of cranial nerves…”
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The development of an EORTC quality of life questionnaire to assess chemotherapy-induced peripheral neuropathy: The QLQ-CIPN20 by Postma, T.J., Aaronson, N.K., Heimans, J.J., Muller, M.J., Hildebrand, J.G., Delattre, J.Y., Hoang-Xuan, K., Lantéri-Minet, M., Grant, R., Huddart, R., Moynihan, C., Maher, J., Lucey, R.

“…Chemotherapy-induced peripheral neuropathy (CIPN) is a common phenomenon, often resulting in serious limitations in daily functioning and comprosised quality…”
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Temozolomide As Initial Treatment for Adults With Low-Grade Oligodendrogliomas or Oligoastrocytomas and Correlation With Chromosome 1p Deletions by HOANG-XUAN, K, CAPELLE, L, CARPENTIER, A. F, LAIGLE, F, SIMON, J. M, CORNU, P, BROËT, P, SANSON, M, DELATTRE, J. Y, KUJAS, M, TAILLIBERT, S, DUFFAU, H, LEJEUNE, J, POLIVKA, M, CRINIERE, E, MARIE, Y, MOKHTARI, K

“…To determine the response rate of low-grade oligodendroglial tumors (LGOT) to temozolomide (TMZ) as initial treatment and to evaluate the predictive value of…”
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Treatment of paraneoplastic neurological syndromes with antineuronal antibodies (Anti-Hu, Anti-Yo) with a combination of immunoglobulins, cyclophosphamide, and methylprednisolone by Keime-Guibert, F, Graus, F, Fleury, A, René, R, Honnorat, J, Broet, P, Delattre, J-Y

“…OBJECTIVES To evaluate the effect of a combination of immunoglobulins (IVIg), cyclophosphamide (CTX), and methylprednisolone (MP) on the clinical course of…”
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Recommended diagnostic criteria for paraneoplastic neurological syndromes by Graus, F, Delattre, J Y, Antoine, J C, Dalmau, J, Giometto, B, Grisold, W, Honnorat, J, Smitt, P Sillevis, Vedeler, Ch, Verschuuren, J J G M, Vincent, A, Voltz, R

“…Background: Paraneoplastic neurological syndromes (PNS) are defined by the presence of cancer and exclusion of other known causes of the neurological symptoms,…”
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Chemotherapy Alone as Initial Treatment for Primary CNS Lymphoma in Patients Older Than 60 Years: A Multicenter Phase II Study (26952) of the European Organization for Research and Treatment of Cancer Brain Tumor Group by HOANG-XUAN, K, TAILLANDIER, L, CHINOT, O, SOUBEYRAN, P, BOGDHAN, U, HILDEBRAND, J, FRENAY, M, DE BEULE, N, DELATTRE, J. Y, BARON, B

“…To assess the efficacy and toxicity of chemotherapy alone in patients older than 60 years with primary CNS lymphoma. Fifty patients with a median age of 72…”
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EFNS Guidelines on diagnosis and treatment of brain metastases: report of an EFNS Task Force by Soffietti, R., Cornu, P., Delattre, J. Y., Grant, R., Graus, F., Grisold, W., Heimans, J., Hildebrand, J., Hoskin, P., Kalljo, M., Krauseneck, P., Marosi, C., Siegal, T., Vecht, C.

“…The objectives have been to establish evidence‐based guidelines and identify controversies regarding the management of patients with brain metastases. The…”
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Low penetrance susceptibility to glioma is caused by the TP53 variant rs78378222 by Enciso-Mora, V, Hosking, F J, Di Stefano, A L, Zelenika, D, Shete, S, Broderick, P, Idbaih, A, Delattre, J-Y, Hoang-Xuan, K, Marie, Y, Labussière, M, Alentorn, A, Ciccarino, P, Rossetto, M, Armstrong, G, Liu, Y, Gousias, K, Schramm, J, Lau, C, Hepworth, S J, Schoemaker, M, Strauch, K, Müller-Nurasyid, M, Schreiber, S, Franke, A, Moebus, S, Eisele, L, Swerdlow, A, Simon, M, Bondy, M, Lathrop, M, Sanson, M, Houlston, R S

“…Background: Most of the heritable risk of glioma is presently unaccounted for by mutations in known genes. In addition to rare inactivating germline mutations…”
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α-Internexin expression identifies 1p19q codeleted gliomas by DUCRAY, F, CRINIERE, E, HOANG-XUAN, K, DELATTRE, J.-Y, SANSON, M, IDBAIH, A, MOKHTARI, K, MARIE, Y, PARIS, S, NAVARRO, S, LAIGLE-DONADEY, F, DEHAIS, C, THILLET, J

“…alpha-Internexin (INA) is a proneural gene encoding a neurofilament interacting protein that is upregulated in some gliomas, particularly oligodendrogliomas…”
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Initial chemotherapy in gliomatosis cerebri by SANSON, M, CARTALAT-CAREL, S, TAILLANDIER, L, CHINOT, O, DUFFAU, H, HONNORAT, J, HOANG-XUAN, K, DELATTRE, J. Y, TAILLIBERT, S, NAPOLITANO, M, DJAFARI, L, COUGNARD, J, GERVAIS, H, LAIGLE, F, CARPENTIER, A, MOKHTARI, K

“…Because of the diffuse nature of gliomatosis cerebri (GC), surgery is not suitable, and large field radiotherapy carries the risk of severe toxicity. In this…”
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Posterior fossa recurrence of WHO grade II and III supratentorial gliomas by Terziev, R., Petrirena, G., Marie, Y., Mueller, W.C., Bielle, F., Delattre, J.-Y.

“…Posterior fossa (PF) recurrences of supratentorial (ST) World Health Organization (WHO) grade II and III gliomas are thought to be rare and to have grim…”
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Supratentorial low-grade gliomas in older patients by Kaloshi, G, Psimaras, D, Mokhtari, K, Dehais, C, Houillier, C, Marie, Y, Laigle-Donadey, F, Taillibert, S, Guillevin, R, Martin-Duverneuil, N, Sanson, M, Hoang-Xuan, K, Delattre, J-Y

“…Low-grade gliomas (LGG) are thought to be very rare in elderly patients (>60 years) and have not been thoroughly studied. A series of 62 elderly (>or=60 years…”
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Long-term clinical outcome of paraneoplastic cerebellar degeneration and anti-Yo antibodies by ROJAS, I, GRAUS, F, KEIME-GUIBERT, F, RENE, R, DELATTRE, J. Y, RAMON, J. M, DALMAU, J, POSNER, J. B

“…The outcome of 34 women with anti-Yo-associated paraneoplastic cerebellar degeneration was reviewed. Three patients had not developed cancer after more than 4…”
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Prediction of Response to Temozolomide in Low‐Grade Glioma Patients Based on Tumor Size Dynamics and Genetic Characteristics by Mazzocco, P, Barthélémy, C, Kaloshi, G, Lavielle, M, Ricard, D, Idbaih, A, Psimaras, D, Renard, M‐A, Alentorn, A, Honnorat, J, Delattre, J‐Y, Ducray, F, Ribba, B

“…Both molecular profiling of tumors and longitudinal tumor size data modeling are relevant strategies to predict cancer patients' response to treatment. Herein…”
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