Search Results - "Delany, James P."
-
1
Diet, microbiota, and microbial metabolites in colon cancer risk in rural Africans and African Americans
Published in The American journal of clinical nutrition (01-07-2013)“…Background: Epidemiologic studies have suggested that most cases of sporadic colon cancer can be attributed to diet. The recognition that colonic microbiota…”
Get full text
Journal Article -
2
Increased Levels of Plasma Acylcarnitines in Obesity and Type 2 Diabetes and Identification of a Marker of Glucolipotoxicity
Published in Obesity (Silver Spring, Md.) (01-09-2010)“…Dysregulation of fatty acid oxidation (FAO) is recognized as important in the pathophysiology of obesity and insulin resistance (IR). However, demonstrating…”
Get full text
Journal Article -
3
Lipolysis of Visceral Adipocyte Triglyceride by Pancreatic Lipases Converts Mild Acute Pancreatitis to Severe Pancreatitis Independent of Necrosis and Inflammation
Published in The American journal of pathology (01-03-2015)“…Visceral fat necrosis has been associated with severe acute pancreatitis (SAP) for over 100 years; however, its pathogenesis and role in SAP outcomes are…”
Get full text
Journal Article -
4
Metabolic and Behavioral Compensations in Response to Caloric Restriction: Implications for the Maintenance of Weight Loss
Published in PloS one (09-02-2009)“…Background: Metabolic and behavioral adaptations to caloric restriction (CR) in free-living conditions have not yet been objectively measured. Methodology and…”
Get full text
Journal Article -
5
Lipotoxicity causes multisystem organ failure and exacerbates acute pancreatitis in obesity
Published in Science translational medicine (02-11-2011)“…Obesity increases the risk of adverse outcomes during acute critical illnesses such as burns, severe trauma, and acute pancreatitis. Although individuals with…”
Get more information
Journal Article -
6
Triheptanoin versus trioctanoin for long-chain fatty acid oxidation disorders: a double blinded, randomized controlled trial
Published in Journal of inherited metabolic disease (01-11-2017)“…Background Observational reports suggest that supplementation that increases citric acid cycle intermediates via anaplerosis may have therapeutic advantages…”
Get full text
Journal Article -
7
Peripancreatic fat necrosis worsens acute pancreatitis independent of pancreatic necrosis via unsaturated fatty acids increased in human pancreatic necrosis collections
Published in Gut (01-01-2016)“…Peripancreatic fat necrosis occurs frequently in necrotising pancreatitis. Distinguishing markers from mediators of severe acute pancreatitis (SAP) is…”
Get more information
Journal Article -
8
The ZJU index is a powerful surrogate marker for NAFLD in severely obese North American women
Published in PloS one (26-11-2019)“…Non-alcoholic fatty liver disease (NAFLD) is the most common chronic liver disease in the western world and is highly associated with multiple cardiometabolic…”
Get full text
Journal Article -
9
Associations between fasting glucose rate-of-change and the missense variant, rs373863828, in an adult Samoan cohort
Published in PloS one (03-06-2024)“…The A allele of rs373863828 in CREB3 regulatory factor is associated with high Body Mass Index, but lower odds of type 2 diabetes. These associations have been…”
Get full text
Journal Article -
10
Source of nicotinamide governs its metabolic fate in cultured cells, mice, and humans
Published in Cell reports (Cambridge) (28-03-2023)“…Metabolic routing of nicotinamide (NAM) to NAD+ or 1-methylnicotinamide (MeNAM) has impacts on human health and aging. NAM is imported by cells or liberated…”
Get full text
Journal Article -
11
Fibrosis Reduces Severity of Acute-on-Chronic Pancreatitis in Humans
Published in Gastroenterology (New York, N.Y. 1943) (01-08-2013)“…Background & Aims Acute pancreatitis (AP) and chronic pancreatitis (CP) share etiologies, but AP can be more severe and is associated with a higher rate of…”
Get full text
Journal Article -
12
Reported Energy Intake Accuracy Compared to Doubly Labeled Water and Usability of the Mobile Food Record among Community Dwelling Adults
Published in Nutrients (22-03-2017)“…The mobile Food Record (mFR) is an image-based dietary assessment method for mobile devices. The study primary aim was to test the accuracy of the mFR by…”
Get full text
Journal Article -
13
Association Between Low Colonic Short-Chain Fatty Acids and High Bile Acids in High Colon Cancer Risk Populations
Published in Nutrition and cancer (01-01-2012)“…We propose that the influence of diet on colon cancer risk is mediated by the microbiota. To investigate how dietary fat influences risk, we compared the…”
Get full text
Journal Article -
14
Effect of physical activity on weight loss, energy expenditure, and energy intake during diet induced weight loss
Published in Obesity (Silver Spring, Md.) (01-02-2014)“…Objective Objective measurements of physical activity (PA), energy expenditure (EE) and energy intake can provide valuable information regarding appropriate…”
Get full text
Journal Article -
15
Effect of Calorie Restriction on Resting Metabolic Rate and Spontaneous Physical Activity
Published in Obesity (Silver Spring, Md.) (01-12-2007)“…Objective: It is unclear if resting metabolic rate (RMR) and spontaneous physical activity (SPA) decrease in weight‐reduced non‐obese participants…”
Get full text
Journal Article -
16
Long-term effects of 2 energy-restricted diets differing in glycemic load on dietary adherence, body composition, and metabolism in CALERIE: a 1-y randomized controlled trial
Published in The American journal of clinical nutrition (01-04-2007)“…BACKGROUND:There remains no consensus about the optimal dietary composition for sustained weight loss. OBJECTIVE:The objective was to examine the effects of 2…”
Get full text
Journal Article -
17
New method for GC/FID and GC–C-IRMS analysis of plasma free fatty acid concentration and isotopic enrichment
Published in Journal of chromatography. B, Analytical technologies in the biomedical and life sciences (15-09-2008)“…A simple, direct and accurate method for the determination of concentration and enrichment of free fatty acids (FFAs) in human plasma was developed. The…”
Get full text
Journal Article -
18
Effect of calorie restriction on the free-living physical activity levels of nonobese humans: results of three randomized trials
Published in Journal of applied physiology (1985) (01-04-2011)“…The objective of this study was to evaluate the influence of calorie restriction (CR) on free-living physical activity levels among humans. Data were from…”
Get full text
Journal Article -
19
Cascades of diabetes and hypertension care in Samoa: Identifying gaps in the diagnosis, treatment, and control continuum – a cross-sectional study
Published in The Lancet regional health. Western Pacific (01-01-2022)“…Samoa is a Pacific Island country facing one of the highest burdens of non-communicable disease globally. In this study, we apply a cascade-of-care approach to…”
Get full text
Journal Article -
20
Differential oxidation of individual dietary fatty acids in humans
Published in The American journal of clinical nutrition (01-10-2000)“…Dietary fatty acids that are more prone to oxidation than to storage may be less likely to lead to obesity. The aim of this study was to determine the effect…”
Get full text
Journal Article