Search Results - "Delaney, Suzanne M."
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Specific inhibition of spleen tyrosine kinase suppresses leukocyte immune function and inflammation in animal models of rheumatoid arthritis
Published in The Journal of pharmacology and experimental therapeutics (01-02-2012)“…Based on genetic studies that establish the role of spleen tyrosine kinase (Syk) in immune function, inhibitors of this kinase are being investigated as…”
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P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
Published in The Journal of clinical investigation (01-08-2003)“…The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y12 antagonists, currently used at doses that block 40-50% of…”
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3
Scientific and therapeutic insights into the role of the platelet P2Y12 receptor in thrombosis
Published in Current opinion in hematology (01-09-2003)“…Platelets are important mediators of thrombosis in both healthy and diseased vessels. When platelets become activated by various soluble agonists or by…”
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Measured visual field extent varies with peripheral stimulus flicker rate in very young children
Published in Optometry and vision science (01-09-2005)“…The purpose of this article is to describe measured visual field extent in very young children in response to variation in peripheral stimulus flicker rate…”
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Implicit Memory for Unfamiliar Objects Depends on Access to Structural Descriptions
Published in Journal of experimental psychology. General (01-03-1990)“…We investigated implicit memory for unfamiliar objects with a task in which subjects decided whether structurally possible and impossible line drawings could…”
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The influence of stimulus size on measured visual field extent in infants
Published in Optometry and vision science (01-10-2003)“…To compare measured visual field extent for a 6 degrees stimulus (typical size used in studies of infants) with a 1.5 degrees stimulus (similar to the largest…”
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The effect of flicker rate on nasal and temporal measured visual field extent in infants
Published in Optometry and vision science (01-12-2004)“…To explore the effect of peripheral stimulus flicker rate on measured visual field extent (MVFE) in young infants. Three hundred sixty infants (180 each at 3.5…”
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A molecularly identified P2Y receptor simultaneously activates phospholipase C and inhibits adenylyl cyclase and is nonselectively activated by all nucleoside triphosphates
Published in Molecular pharmacology (01-04-2000)“…We recently cloned and expressed a novel P2Y receptor (tp2y receptor) from a turkey cDNA library. Expression of this receptor in 1321N1 human astrocytoma cells…”
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9
P2Y12 regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
Published in The Journal of clinical investigation (01-08-2003)“…The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y 12 antagonists, currently used at doses that block 40–50%…”
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10
Implicit Memory for Possible and Impossible Objects: Constraints on the Construction of Structural Descriptions
Published in Journal of experimental psychology. Learning, memory, and cognition (01-01-1991)“…Four experiments examined implicit memory or priming effects on an object decision task in which subjects decided whether structurally possible or impossible…”
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11
The effect of flicker rate on measured visual field extent in very young children
Published in Optometry and vision science (01-11-2001)“…To investigate the effect of flicker rate on measured visual field extent in toddlers. A total of 270 full-term children (90 each at 11-, 17-, and 30-months of…”
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12
Diadenosine polyphosphates inhibit adenosine kinase activity but decrease levels of endogenous adenosine in rat brain
Published in European journal of pharmacology (30-07-1997)“…Findings in peripheral tissues that diadenosine polyphosphates (Ap n As) activate 5′-nucleotidase activity and inhibit adenosine kinase activity in vitro led…”
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13
Stimulus motion increases measured visual field extent in children 3.5 to 30 months of age
Published in Optometry and vision science (01-02-2000)“…To examine the influence of stimulus motion on measured visual field extent of 3.5- to 30-month-old children and adults. Each subject was tested with…”
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14
Does rate of stimulus presentation affect measured visual field extent in infants and toddlers?
Published in Optometry and vision science (01-04-1999)“…To evaluate the effect of stimulus presentation rate on the measurement of visual field extent in infants and toddlers. Visual field extent was measured for…”
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15
Anticoagulants (Thrombin Inhibitors) and Aspirin Synergize With P2Y 12 Receptor Antagonism in Thrombosis
Published in Circulation (New York, N.Y.) (25-11-2003)“…Background— This study was designed to determine whether (1) P2Y 12 antagonism synergizes with other antithrombotics and (2) anticoagulants (thrombin…”
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P2Y^sub 12^ regulates platelet adhesion/activation, thrombus growth, and thrombus stability in injured arteries
Published in The Journal of clinical investigation (01-08-2003)“…The critical role for ADP in arterial thrombogenesis was established by the clinical success of P2Y12 antagonists, currently used at doses that block 40-50% of…”
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Antithrombotic Activity of PRT54021, a Potent Oral Direct Factor Xa Inhibitor, Can Be Monitored Using a Novel Prothrombinase Inhibition Bioassay
Published in Blood (16-11-2006)“…Coagulation factor Xa (fXa) is a validated target for antithrombotic therapy and there are several on-going clinical trials testing direct fXa inhibitors…”
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18
Brain regional levels of adenosine and adenosine nucleotides in rats killed by high-energy focused microwave irradiation
Published in Journal of neuroscience methods (01-02-1996)“…A high-energy focused microwave system for killing experimental animals was used to rapidly inactivate enzymes and prevent postmortem breakdown of adenine…”
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Anticoagulants (thrombin inhibitors) and aspirin synergize with P2Y12 receptor antagonism in thrombosis
Published in Circulation (New York, N.Y.) (25-11-2003)“…This study was designed to determine whether (1) P2Y12 antagonism synergizes with other antithrombotics and (2) anticoagulants (thrombin inhibitors) affect the…”
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20
Enhancement of NMDA-induced increases in levels of endogenous adenosine by adenosine deaminase and adenosine transport inhibition in rat striatum
Published in Brain research (08-12-1995)“…Unilateral microinjection of N-methyl- d-aspartate (NMDA) into striatum of rats subsequently killed by high-energy focused microwave irradiation significantly…”
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