Search Results - "Delaney, Sean P."

Terahertz Spectroscopy and Computational Investigation of the Flufenamic Acid/Nicotinamide Cocrystal by Delaney, Sean P, Korter, Timothy M

“…Terahertz spectroscopy probes the low-frequency vibrations that are sensitive to both the intermolecular and intramolecular interactions of molecules in the…”
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Metabolism of salicylic acid in wild-type, ugt74f1 and ugt74f2 glucosyltransferase mutants of Arabidopsis thaliana by Dean, John V, Delaney, Sean P

“…Arabidopsis thaliana contains two salicylic acid (SA) glucosyltransferase enzymes designated UGT74F1 and UGT74F2. UGT74F1 forms only SA 2-O-β-D-glucose (SAG),…”
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Lasting differential gene expression of circulating CD8 T cells in chronic HCV infection with cirrhosis identifies a role for Hedgehog signaling in cellular hyperfunction by Li, Jiafeng, Vranjkovic, Agatha, Read, Daniel, Delaney, Sean P, Stanford, William L, Cooper, Curtis L, Crawley, Angela M

“…The impact of chronic hepatic infection on antigen non-specific immune cells in circulation remains poorly understood. We reported lasting global hyperfunction…”
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Evaluating the Roles of Conformational Strain and Cohesive Binding in Crystalline Polymorphs of Aripiprazole by Delaney, Sean P, Pan, Duohai, Yin, Shawn X, Smith, Tiffany M, Korter, Timothy M

“…The relative stabilities of crystalline polymorphs are an important aspect of the manufacturing and effective utilization of pharmaceuticals. These stabilities…”
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Understanding the Origins of Conformational Disorder in the Crystalline Polymorphs of Irbesartan by Delaney, Sean P, Pan, Duohai, Galella, Michael, Yin, Shawn X, Korter, Timothy M

“…The characterization of crystalline polymorphs of drug molecules is an area of great interest since these variations in solid-state structure directly…”
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Human Pluripotent Stem Cell-Derived TSC2 -Haploinsufficient Smooth Muscle Cells Recapitulate Features of Lymphangioleiomyomatosis by Julian, Lisa M, Delaney, Sean P, Wang, Ying, Goldberg, Alexander A, Doré, Carole, Yockell-Lelièvre, Julien, Tam, Roger Y, Giannikou, Krinio, McMurray, Fiona, Shoichet, Molly S, Harper, Mary-Ellen, Henske, Elizabeth P, Kwiatkowski, David J, Darling, Thomas N, Moss, Joel, Kristof, Arnold S, Stanford, William L

“…Lymphangioleiomyomatosis (LAM) is a progressive destructive neoplasm of the lung associated with inactivating mutations in the or tumor suppressor genes. Cell…”
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Investigating Tautomeric Polymorphism in Crystalline Anthranilic Acid Using Terahertz Spectroscopy and Solid-State Density Functional Theory by Delaney, Sean P, Witko, Ewelina M, Smith, Tiffany M, Korter, Timothy M

“…Terahertz spectroscopy is sensitive to the interactions between molecules in the solid-state and recently has emerged as a new analytical tool for…”
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SARS-CoV-2 antigen-carrying extracellular vesicles activate T cell responses in a human immunogenicity model by Cummings, Sarah E., Delaney, Sean P., St-Denis Bissonnette, Frederic, Stalker, Andrew, Muradia, Gauri, Mehic, Jelica, Graber, Tyson E., Alain, Tommy, Lavoie, Jessie R.

“…Extracellular vesicles (EVs) are entering the clinical arena as novel biologics for infectious diseases, potentially serving as the immunogenic components of…”
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Terahertz Vibrational Modes of the Rigid Crystal Phase of Succinonitrile by Nickel, Daniel V, Delaney, Sean P, Bian, Hongtao, Zheng, Junrong, Korter, Timothy M, Mittleman, Daniel M

“…Succinonitrile (NC–CH2–CH2–CN), an orientationally disordered molecular plastic crystal at room temperature, exhibits rich phase behavior including a…”
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Tissue-Engineered Disease Modeling of Lymphangioleiomyomatosis Exposes a Therapeutic Vulnerability to HDAC Inhibition by Pietrobon, Adam, Yockell-Lelièvre, Julien, Melong, Nicole, Smith, Laura J, Delaney, Sean P, Azzam, Nadine, Xue, Chang, Merwin, Nishanth, Lian, Eric, Camacho-Magallanes, Alberto, Doré, Carole, Musso, Gabriel, Julian, Lisa M, Kristof, Arnold S, Tam, Roger Y, Berman, Jason N, Shoichet, Molly S, Stanford, William L

“…Lymphangioleiomyomatosis (LAM) is a rare disease involving cystic lung destruction by invasive LAM cells. These cells harbor loss-of-function mutations in…”
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The neural crest lineage as a driver of disease heterogeneity in Tuberous Sclerosis Complex and Lymphangioleiomyomatosis by Delaney, Sean P, Julian, Lisa M, Stanford, William L

“…Lymphangioleiomyomatosis (LAM) is a rare neoplastic disease, best characterized by the formation of proliferative nodules that express smooth muscle and…”
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Could Immunotherapy Sink Its Teeth into Lymphangioleiomyomatosis? by Pietrobon, Adam, Delaney, Sean P, Stanford, William L

“…Pulmonary lymphangioleiomyomatosis (LAM) is an invasive neoplasm that occurs virtually exclusively in women. LAM is characterized by proliferating, atypical…”
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Regioselective Baeyer–Villiger oxidation of lignin model compounds with tin beta zeolite catalyst and hydrogen peroxide by Jennings, John A., Parkin, Sean, Munson, Eric, Delaney, Sean P., Calahan, Julie L., Isaacs, Mark, Hong, Kunlun, Crocker, Mark

“…Lignin depolymerization represents a promising approach to the sustainable production of aromatic molecules. One potential approach to the stepwise…”
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Using Terahertz Spectroscopy and Solid-State Density Functional Theory to Characterize a New Polymorph of 5‑(4-pyridyl)tetrazole by Pellizzeri, Steven, Delaney, Sean P, Korter, Timothy M, Zubieta, Jon

“…A new high-temperature polymorph of 5-(4-pyridyl)­tetrazole has been discovered and characterized using X-ray crystallography and terahertz (THz) spectroscopy…”
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Conformational origins of polymorphism in two forms of flufenamic acid by Delaney, Sean P., Smith, Tiffany M., Korter, Timothy M.

“…[Display omitted] •Polymorphs of flufenamic acid have been studied using THz spectroscopy and solid-state theory.•Molecular conformation drives the formation…”
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Low-Temperature Phase Transition in Crystalline Aripiprazole Leads to an Eighth Polymorph by Delaney, Sean P, Smith, Tiffany M, Pan, Duohai, Yin, Shawn X, Korter, Timothy M

“…A new crystalline polymorph (Form VIII) of the antidepressant drug aripiprazole has been discovered, resulting from a previously unknown enantiotropic phase…”
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Characterization of Synthesized and Commercial Forms of Magnesium Stearate Using Differential Scanning Calorimetry, Thermogravimetric Analysis, Powder X-Ray Diffraction, and Solid-State NMR Spectroscopy by Delaney, Sean P, Nethercott, Matthew J, Mays, Christopher J, Winquist, Nickolas T, Arthur, Donia, Calahan, Julie L, Sethi, Manish, Pardue, Daniel S, Kim, Junghyun, Amidon, Gregory, Munson, Eric J

“…Magnesium stearate is the salt of a complex mixture of fatty acids, with the majority being stearate and palmitate. It has multiple crystalline forms and,…”
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A Facile Microwave Assisted TEMPO/NaOCl/Oxone (KHSO5) Mediated Micron Cellulose Oxidation Procedure: Preparation of Two Nano TEMPO‐Cellulose Forms by Dachavaram, Soma Shekar, Moore, John P., Bommagani, Shobanbabu, Penthala, Narsimha R., Calahan, Julie L., Delaney, Sean P., Munson, Eric J., Batta‐Mpouma, Joseph, Kim, Jin‐Woo, Hestekin, Jamie A., Crooks, Peter A.

“…An efficient and rapid method is established for micron cellulose (1, 20 microns) oxidation utilizing Oxone (KHSO5) in combination with…”
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Synthesis and characterization of thermally responsive N-isopropylacrylamide hydrogels copolymerized with novel hydrophobic polyphenolic crosslinkers by Tang, Shuo, Bhandari, Rohit, Delaney, Sean P., Munson, Eric J., Dziubla, Thomas D., Hilt, J. Zach

“…Two series of thermosensitive hydrogels were synthesized by copolymerizing N-isopropylacrylamide (NIPAAm) with various contents of novel hydrophobic…”
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Abstract 2974: Loss of TSC1 or TSC2 drives lineage infidelity and hamartoma formation in a renal organoid model of angiomyolipoma by Pietrobon, Adam, Delaney, Sean P., Doré, Carole, Yockell-Lelievre, Julien, Julian, Lisa, Stanford, William L.

“…Renal angiomyolipomas (R-AMLs) are hamartomatous kidney tumors which stain positively for markers of adipocytic, vascular, smooth muscle, and melanocytic…”
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