Search Results - "Delaney, K K"
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Reflectance Hyperspectral Imaging for Investigation of Works of Art: Old Master Paintings and Illuminated Manuscripts
Published in Accounts of chemical research (18-10-2016)“…Diffuse reflectance hyperspectral imaging, or reflectance imaging spectroscopy, is a sophisticated technique that enables the capture of hundreds of images in…”
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2
Flexible parsing, interpretation, and editing of technical sequences with splitcode
Published in Bioinformatics (Oxford, England) (03-06-2024)“…Abstract Motivation Next-generation sequencing libraries are constructed with numerous synthetic constructs such as sequencing adapters, barcodes, and unique…”
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mTOR inhibition attenuates chemosensitivity through the induction of chemotherapy resistant persisters
Published in Nature communications (17-11-2022)“…Chemotherapy can eradicate a majority of cancer cells. However, a small population of tumor cells often survives drug treatments through genetic and/or…”
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4
Anisotropic conductance at improper ferroelectric domain walls
Published in Nature materials (26-02-2012)“…Oxide materials show a versatile range of phenomena that in many cases can be controlled by growing thin films of oxides next to each other. The observation…”
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Stable internal reference genes for normalization of real-time RT-PCR in tobacco (Nicotiana tabacum) during development and abiotic stress
Published in Molecular genetics and genomics : MGG (01-03-2010)“…Real-time RT-PCR is a powerful technique for the measurement of gene expression, but its accuracy depends on the stability of the internal reference gene(s)…”
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Oncogene KRAS activates fatty acid synthase, resulting in specific ERK and lipid signatures associated with lung adenocarcinoma
Published in Proceedings of the National Academy of Sciences - PNAS (25-04-2017)“…KRAS gene mutation causes lung adenocarcinoma. KRAS activation has been associated with altered glucose and glutamine metabolism. Here, we show that KRAS…”
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The MYC Oncogene Cooperates with Sterol-Regulated Element-Binding Protein to Regulate Lipogenesis Essential for Neoplastic Growth
Published in Cell metabolism (03-09-2019)“…Lipid metabolism is frequently perturbed in cancers, but the underlying mechanism is unclear. We present comprehensive evidence that oncogene MYC, in…”
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Acquisition of High Spectral Resolution Diffuse Reflectance Image Cubes (350-2500 nm) from Archaeological Wall Paintings and Other Immovable Heritage Using a Field-Deployable Spatial Scanning Reflectance Spectrometry Hyperspectral System
Published in Sensors (Basel, Switzerland) (01-03-2022)“…There is growing interest in bringing non-invasive laboratory-based analytical imaging tools to field sites to study wall paintings in order to collect…”
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Inhibition of ERAD synergizes with FTS to eradicate pancreatic cancer cells
Published in BMC cancer (06-03-2021)“…Pancreatic ductal adenocarcinoma (PDAC), one of the most lethal cancers, is driven by oncogenic KRAS mutations. Farnesyl thiosalicylic acid (FTS), also known…”
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Cocaine regulation of Nr4a1 chromatin bivalency and mRNA in male and female mice
Published in Scientific reports (21-09-2022)“…Cocaine epigenetically regulates gene expression via changes in histone post-translational modifications (HPTMs). We previously found that the immediate early…”
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Nuclear to cytoplasmic transport is a druggable dependency in MYC-driven hepatocellular carcinoma
Published in Nature communications (01-02-2024)“…The MYC oncogene is often dysregulated in human cancer, including hepatocellular carcinoma (HCC). MYC is considered undruggable to date. Here, we…”
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A platform for high-throughput screening of DNA-encoded catalyst libraries in organic solvents
Published in Chemical science (Cambridge) (01-10-2017)“…We have developed a novel high-throughput screening platform for the discovery of small-molecules catalysts for bond-forming reactions. The method employs an…”
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Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum
Published in Nature communications (13-12-2022)“…Epigenetic gene regulation in the heterogeneous brain remains challenging to decipher with current strategies. Bulk tissue analysis from pooled subjects…”
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Scaling Behavior and Beyond Equilibrium in the Hexagonal Manganites
Published in Physical review. X (27-12-2012)“…We show that the improper ferroelectric phase transition in the multiferroic hexagonal manganites displays appropriate symmetry-breaking characteristics for…”
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Author Correction: Cell-type specific profiling of histone post-translational modifications in the adult mouse striatum
Published in Nature communications (22-02-2023)Get full text
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Automatic registration and mosaicking of technical images of Old Master paintings
Published in Applied physics. A, Materials science & processing (01-06-2015)“…The registration of technical art conservation images of Old Master paintings presents unique challenges. Specifically, X-radiographs and reflective infrared…”
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Selective Labeling and Identification of the Tumor Cell Proteome of Pancreatic Cancer In Vivo
Published in Journal of proteome research (01-01-2021)“…Pancreatic ductal adenocarcinoma (PDAC) is among the deadliest cancers. Dissecting the tumor cell proteome from that of the non-tumor cells in the PDAC tumor…”
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Chromatin-mediated alternative splicing regulates cocaine-reward behavior
Published in Neuron (Cambridge, Mass.) (15-09-2021)“…Neuronal alternative splicing is a key gene regulatory mechanism in the brain. However, the spliceosome machinery is insufficient to fully specify splicing…”
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MYC-driven synthesis of Siglec ligands is a glycoimmune checkpoint
Published in Proceedings of the National Academy of Sciences - PNAS (14-03-2023)“…The Siglecs (sialic acid-binding immunoglobulin-like lectins) are glycoimmune checkpoint receptors that suppress immune cell activation upon engagement of…”
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Randomized controlled trial of computerized approach/avoidance training in social anxiety disorder: Neural and symptom outcomes
Published in Journal of affective disorders (01-03-2023)“…Social anxiety is associated with diminished automatic approach toward positive social cues that may limit the ability to connect with others. This diminished…”
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