Search Results - "Delaney, Jeannine"

Fluorescence imaging of bombesin and transferrin receptor expression is comparable to 18F-FDG PET in early detection of sorafenib-induced changes in tumor metabolism by Tseng, Jen-Chieh, Narayanan, Nara, Ho, Guojie, Groves, Kevin, Delaney, Jeannine, Bao, Bagna, Zhang, Jun, Morin, Jeffrey, Kossodo, Sylvie, Rajopadhye, Milind, Peterson, Jeffrey D

“…Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models…”
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A fluorogenic near-infrared imaging agent for quantifying plasma and local tissue renin activity in vivo and ex vivo by Zhang, Jun, Preda, Dorin V, Vasquez, Kristine O, Morin, Jeff, Delaney, Jeannine, Bao, Bagna, Percival, M David, Xu, Daigen, McKay, Dan, Klimas, Michael, Bednar, Bohumil, Sur, Cyrille, Gao, David Z, Madden, Karen, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D

“…The renin-angiotensin system (RAS) is well studied for its regulation of blood pressure and fluid homeostasis, as well as for increased activity associated…”
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Capillary electrophoresis/electrospray ion trap mass spectrometry for the analysis of negatively charged derivatized and underivatized glycans by Gennaro, Lynn A., Delaney, Jeannine, Vouros, Paul, Harvey, David J., Domon, Bruno

“…The increasing interest in the development of glycoproteins for therapeutic purposes has created a greater demand for methods to characterize the sugar…”
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Noninvasive In Vivo Quantification of Neutrophil Elastase Activity in Acute Experimental Mouse Lung Injury by Kossodo, Sylvie, Zhang, Jun, Groves, Kevin, Cuneo, Garry J., Handy, Emma, Morin, Jeff, Delaney, Jeannine, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D.

“…We developed a neutrophil elastase-specific near-infrared fluorescence imaging agent, which, combined with fluorescence molecular tomographic imaging, allowed…”
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Blood Pharmacokinetics Imaging by Noninvasive Heart Fluorescence Tomography and Application to Kidney Glomerular Filtration Rate Assessment by Bao, Bagna, Vasquez, Kristine O, Ho, Guojie, Zhang, Jun, Delaney, Jeannine, Rajopadhye, Milind, Peterson, Jeffrey D

“…In mouse pharmacokinetic (PK) studies, current standard methods often require large numbers of animals to support collection of blood samples serially over a…”
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Fluorescence imaging of bombesin and transferrin receptor expression is comparable to .sup.18F-FDG PET in early detection of sorafenib-induced changes in tumor metabolism by Tseng, Jen-Chieh, Narayanan, Nara, Ho, Guojie, Groves, Kevin, Delaney, Jeannine, Bao, Bagna, Zhang, Jun, Morin, Jeffrey, Kossodo, Sylvie, Rajopadhye, Milind, Peterson, Jeffrey D

“…Physical measurement of tumor volume reduction is the most commonly used approach to assess tumor progression and treatment efficacy in mouse tumor models…”
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Abstract 4939: Detection and quantification of enzymatically active tissue prostate-specific antigen in vivo by Peterson, Jeffrey D., Ho, Guojie, Morin, Jeffrey, Delaney, Jeannine, Yared, Wael, Rajopadhye, Milind, Kossodo, Sylvie C.

“…Prostate-Specific Antigen (PSA) is a 237 amino acid, 33 kDa, extracellular serine protease expressed in prostate epithelial tissue. In the normal prostate,…”
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Abstract 4934: Imaging and quantification of bombesin receptor expression in vivo using a NIR-labeled bombesin peptide by Peterson, Jeffrey D., Narayanan, Nara, Delaney, Jeannine, Morin, Jeffrey, Rajopadhye, Milind, Yared, Wael, Kossodo, Sylvie

“…Gastrin-releasing peptide (GRP) is one of the mammalian analogs of bombesin-like peptides that function as growth factors in normal and neoplastic tissues upon…”
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Detection and quantification of enzymatically active prostate-specific antigen in vivo by Ho, Guojie, Morin, Jeffrey, Delaney, Jeannine, Cuneo, Garry, Yared, Wael, Rajopadhye, Milind, Peterson, Jeffrey D, Kossodo, Sylvie

“…Assays for blood levels of prostate-specific antigen (PSA), performed in prostate cancer detection, measure mostly inactive/complexed PSA and do not provide…”
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Abstract LB-511: In vivo imaging of tumor vasculature with a novel near infra-red lectin agent by Morin, Jeffrey, Delaney, Jeannine, Ho, Guojie, Cuneo, Garry, Rajopadhye, Milind, Yared, Wael, Peterson, Jeffrey D., Kossodo, Sylvie C.

“…Tumors induce significant blood vessel development in order to support their aggressive growth and progression, and the extensive and disordered nature of…”
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Abstract 4888: Development of a novel FAST cathepsin-activatable NIR agent for tumor imaging by Kossodo, Sylvie C., Morin, Jeffrey, Delaney, Jeannine, Cuneo, Garry, Handy, Emma, Groves, Kevin, Zhang, Jun, Rajopadhye, Milind, Yared, Wael, Peterson, Jeffrey D.

“…Fluorescence molecular tomography (FMT) and near-infrared (NIR) imaging agents enable the quantification of kinetic changes in tumor biology in vivo,…”
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Liquid chromatography ion trap mass spectrometric analysis of oligosaccharides using permethylated derivatives by Delaney, Jeannine, Vouros, Paul

“…Reversed phase liquid chromatography was combined with the multiple stage mass analysis capability of an ion trap mass spectrometer for the characterization of…”
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Abstract 4556: Fast-activating cathepsin B optical agent for quantitative in vivo imaging of tumor and therapeutic response by Groves, Kevin, Morin, Jeff, Zhang, Jun, Handy, Emma, Delaney, Jeannine, Kossodo, Sylvie, Bao, Bagna, Cuneo, Gary, Peterson, Jeffrey D., Rajopadhye, Milind, Madden, Karen, Gao, David Z.

“…Cathepsin (Cat) B, a lysosomal cysteine protease, is strongly overexpressed in cancers and premalignant lesions and associated with cancer growth,…”
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Abstract 4557: In vivo near-infrared fluorescent quantification of therapy-induced apoptosis using Annexin-Vivo 750 by Zhang, Jun, Cuneo, Gary, Narayanan, Nara, Delaney, Jeannine, Kossodo, Sylvie, Bao, Bagna, Rajopadhye, Milind, Peterson, Jeffrey D., Madden, Karen, Gao, David Z., Moonen, Peter, Reutelingsperger, Chris

“…Drug-induced ex vivo apoptotic tests are widely used pre-clinically to monitor chemotherapeutic efficacy. Real-time non-invasive in vivo imaging and…”
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Expression, purification, and characterization of rat interferon-β, and preparation of an N-terminally PEGylated form with improved pharmacokinetic parameters by Arduini, Robert M, Li, Zhifang, Rapoza, Alan, Gronke, Robert, Hess, Donna M, Wen, Dingyi, Miatkowski, Konrad, Coots, Caroline, Kaffashan, Azita, Viseux, Nelly, Delaney, Jeannine, Domon, Bruno, Young, Carmen N, Boynton, Raymond, Chen, Ling Ling, Chen, Liqing, Betzenhauser, Matthew, Miller, Stephan, Gill, Alan, Pepinsky, R.Blake, Hochman, Paula S, Baker, Darren P

“…To identify potential new clinical uses and routes of administration for human interferon-β-1a (IFN-β-1a), we have developed an expression and purification…”
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Efficient Use of the Iron Ortho-Nitrophenylporphyrin Chloride to Mimic Biological Oxidations of Dimethylaminoantipyrine by Bazin, Marc J., Shi, Helen, Delaney, Jeannine, Kline, Billie, Zhu, Zhendong, Kuhn, Cyrille, Berlioz, Francoise, Farley, Kathleen A., Fate, Gwen, Lam, Wing, Walker, Gregory S., Yu, Linning, Pollastri, Michael P.

“…Major metabolites of dimethylaminoantipyrine have been synthesized using iron ortho‐nitrophenylporphyrin chloride as biomimetic catalyst. Reactivity of iron…”
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