Search Results - "Dela Cruz, Charles S"

Mechanosensation of cyclical force by PIEZO1 is essential for innate immunity by Solis, Angel G., Bielecki, Piotr, Steach, Holly R., Sharma, Lokesh, Harman, Christian C. D., Yun, Sanguk, de Zoete, Marcel R., Warnock, James N., To, S. D. Filip, York, Autumn G., Mack, Matthias, Schwartz, Martin A., Dela Cruz, Charles. S., Palm, Noah W., Jackson, Ruaidhrí, Flavell, Richard A.

“…Direct recognition of invading pathogens by innate immune cells is a critical driver of the inflammatory response. However, cells of the innate immune system…”
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Diagnosis and Management of COVID-19 Disease by Jamil, Shazia, Mark, Nick, Carlos, Graham, Cruz, Charles S Dela, Gross, Jane E, Pasnick, Susan

“…SARS-CoV-2 is a novel coronavirus that was identified in late 2019 as the causative agent of COVID-19 (aka coronavirus disease 2019). On March 11, 2020, the…”
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Innate Immunity of the Lung: From Basic Mechanisms to Translational Medicine by Hartl, Dominik, Tirouvanziam, Rabindra, Laval, Julie, Greene, Catherine M., Habiel, David, Sharma, Lokesh, Yildirim, Ali Önder, Dela Cruz, Charles S., Hogaboam, Cory M.

“…The respiratory tract is faced daily with 10,000 L of inhaled air. While the majority of air contains harmless environmental components, the pulmonary immune…”
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Chitinase 3-like-1 Promotes Streptococcus pneumoniae Killing and Augments Host Tolerance to Lung Antibacterial Responses by Dela Cruz, Charles S., Liu, Wei, He, Chuan Hua, Jacoby, Adam, Gornitzky, Alex, Ma, Bing, Flavell, Richard, Lee, Chun Geun, Elias, Jack A.

“…Host antibacterial responses include mechanisms that kill bacteria, but also those that protect or tolerize the host to potentially damaging antibacterial…”
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Glucocorticoid Therapy in COVID-19 by Amati, Francesco, Tonutti, Antonio, Huston, John, Dela Cruz, Charles S

“…Coronavirus disease 2019 (COVID-19) pneumonia caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has resulted in significant mortality in…”
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COVID-19: How Do We Stay Safe? by Carlos, W Graham, Cruz, Charles S Dela, Cao, Bin, Gross, Jane E, Pasnick, Susan, Jamil, Shazia

“…COVID-19 is a disease resulting from infection with a coronavirus named SARS-CoV-2. This disease can cause many symptoms but most notably respiratory symptoms…”
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Circulating markers of angiogenesis and endotheliopathy in COVID-19 by Pine, Alexander B., Meizlish, Matthew L., Goshua, George, Chang, C-Hong, Zhang, Hanming, Bishai, Jason, Bahel, Parveen, Patel, Amisha, Gbyli, Rana, Kwan, Jennifer M., Won, Christine H., Price, Christina, Dela Cruz, Charles S., Halene, Stephanie, van Dijk, David, Hwa, John, Lee, Alfred I., Chun, Hyung J.

“…Increase in thrombotic and microvascular complications is emerging to be a key feature of patients with critical illness associated with COVID-19 infection…”
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Protecting health-care workers from subclinical coronavirus infection by Chang, De, Xu, Huiwen, Rebaza, Andre, Sharma, Lokesh, Dela Cruz, Charles S

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Epidemiologic and Clinical Characteristics of Novel Coronavirus Infections Involving 13 Patients Outside Wuhan, China by Chang, De, Lin, Minggui, Wei, Lai, Xie, Lixin, Zhu, Guangfa, Dela Cruz, Charles S, Sharma, Lokesh

“…This case series uses patient hospital data to summarize the clinical presentation and laboratory and imaging findings of 13 patients with confirmed 2019-nCoV…”
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Single-cell characterization of a model of poly I:C-stimulated peripheral blood mononuclear cells in severe asthma by Chen, Ailu, Diaz-Soto, Maria P, Sanmamed, Miguel F, Adams, Taylor, Schupp, Jonas C, Gupta, Amolika, Britto, Clemente, Sauler, Maor, Yan, Xiting, Liu, Qing, Nino, Gustavo, Cruz, Charles S Dela, Chupp, Geoffrey L, Gomez, Jose L

“…Asthma has been associated with impaired interferon response. Multiple cell types have been implicated in such response impairment and may be responsible for…”
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Regulation and Role of Chitotriosidase during Lung Infection with Klebsiella pneumoniae by Sharma, Lokesh, Amick, Alyssa K, Vasudevan, Swathy, Lee, Sei Won, Marion, Chad R, Liu, Wei, Brady, Virginia, Losier, Ashley, Bermejo, Santos D, Britto, Clemente J, Lee, Chun Geun, Elias, Jack A, Dela Cruz, Charles S

“…Chitinases and chitinase-like proteins are an evolutionary conserved group of proteins. In the absence of chitin synthesis in mammals, the conserved presence…”
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MKK3 regulates mitochondrial biogenesis and mitophagy in sepsis-induced lung injury by Mannam, Praveen, Shinn, Amanda S, Srivastava, Anup, Neamu, Radu F, Walker, Wendy E, Bohanon, Michael, Merkel, Jane, Kang, Min-Jong, Dela Cruz, Charles S, Ahasic, Amy M, Pisani, Margaret A, Trentalange, Mark, West, A Phillip, Shadel, Gerald S, Elias, Jack A, Lee, Patty J

“…Sepsis is a systemic inflammatory response to infection and a major cause of death worldwide. Because specific therapies to treat sepsis are limited, and…”
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The kinetics of humoral response and its relationship with the disease severity in COVID-19 by Ren, Lili, Zhang, Lulu, Chang, De, Wang, Junwen, Hu, Yongfeng, Chen, Hong, Guo, Li, Wu, Chao, Wang, Conghui, Wang, Yingying, Wang, Ying, Wang, Geng, Yang, Siyuan, Dela Cruz, Charles S., Sharma, Lokesh, Wang, Linghang, Zhang, Dingyu, Wang, Jianwei

“…Coronavirus Disease 2019 (COVID-19) has caused a global pandemic. Here we profiled the humoral response against Severe Acute Respiratory Syndrome Coronavirus 2…”
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Clinical Epidemiology, Risk Factors, and Control Strategies of Klebsiella pneumoniae Infection by Chang, De, Sharma, Lokesh, Dela Cruz, Charles S, Zhang, Dong

“…species cause infections at multiple sites, including lung, urinary tract, bloodstream, wound or surgical site, and brain. These infections are more likely to…”
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Chitin and Its Effects on Inflammatory and Immune Responses by Elieh Ali Komi, Daniel, Sharma, Lokesh, Dela Cruz, Charles S.

“…Chitin, a potential allergy-promoting pathogen-associated molecular pattern (PAMP), is a linear polymer composed of N -acetylglucosamine residues which are…”
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Profiling Early Humoral Response to Diagnose Novel Coronavirus Disease (COVID-19) by Guo, Li, Ren, Lili, Yang, Siyuan, Xiao, Meng, Chang, De, Yang, Fan, Dela Cruz, Charles S, Wang, Yingying, Wu, Chao, Xiao, Yan, Zhang, Lulu, Han, Lianlian, Dang, Shengyuan, Xu, Yan, Yang, Qi-Wen, Xu, Sheng-Yong, Zhu, Hua-Dong, Xu, Ying-Chun, Jin, Qi, Sharma, Lokesh, Wang, Linghang, Wang, Jianwei

“…Abstract Background The emergence of coronavirus disease 2019 (COVID-19) is a major healthcare threat. The current method of detection involves a quantitative…”
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Mitochondrial dysfunction and damage associated molecular patterns (DAMPs) in chronic inflammatory diseases by Dela Cruz, Charles S, Kang, Min-Jong

“…Inflammation represents a comprehensive host response to external stimuli for the purpose of eliminating the offending agent, minimizing injury to host tissues…”
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Epithelial cell-derived microvesicles activate macrophages and promote inflammation via microvesicle-containing microRNAs by Lee, Heedoo, Zhang, Duo, Zhu, Ziwen, Dela Cruz, Charles S., Jin, Yang

“…Intercellular communications between lung epithelial cells and alveolar macrophages play an essential role in host defense against acute lung injury…”
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Context‐specific anti‐inflammatory roles of type III interferon signaling in the lung in nonviral injuries by Feng, Jingjing, Kim, Jooyoung, Wang, Victoria D., Chang, De, Liu, Hongbo, Bain, William G., Robinson, Keven M., Jie, Zhijun, Kotenko, Sergei V., Dela Cruz, Charles S., Sharma, Lokesh

“…Type III interferons (λ1, λ2, and λ3) are potent antiviral cytokines in the lung. However, their roles in nonviral lung injuries are less well understood. This…”
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Role of breast regression protein-39 in the pathogenesis of cigarette smoke-induced inflammation and emphysema by Matsuura, Hiroshi, Hartl, Dominik, Kang, Min-Jong, Dela Cruz, Charles S, Koller, Barbara, Chupp, Geoffrey L, Homer, Robert J, Zhou, Yang, Cho, Won-Kyung, Elias, Jack A, Lee, Chun Geun

“…The exaggerated expression of chitinase-like protein YKL-40, the human homologue of breast regression protein-39 (BRP-39), was reported in a number of…”
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